Results 81 to 90 of about 113,937,690 (201)

Oseltamivir-resistant influenza A(H1N1)pdm09 virus in southern Brazil [PDF]

Memórias do Instituto Oswaldo Cruz, 2013
The neuraminidase (NA) genes of A(H1N1)pdm09 influenza virus isolates from 306 infected patients were analysed. The circulation of oseltamivir-resistant viruses in Brazil has not been reported previously. Clinical samples were collected in the state of Rio Grande do Sul (RS) from 2009-2011 and two NA inhibitor-resistant mutants were identified, one in ...
Marx, Camila, Gregianini, Tatiana Schaffer, Lehmann, Fernanda Kieling Moreira, Lunge, Vagner Ricardo, Carli, Silvia de, Dambros, Bibiana Paula, Tumioto, Gabriela Luchiari, Seadi, Claudete, Fonseca, Andre Salvador Kazantzi, Ikuta, Nilo   +9 more
openaire   +5 more sources

Differences in Glycoproteins and the Potential for Early Protection Using LAIV Based on Drift Variants of the A/H1N1pdm09 Influenza Virus

Vaccines
Background/Objectives: Antigenic drift of influenza A(H1N1pdm09) viruses has led to periodic replacement of vaccine strains. Understanding how structural differences in glycoproteins influence immune protection is crucial for improving vaccine ...
Yulia Desheva, Irina Mayorova, Andrey Rekstin, Daniil Sokolovsky, Polina Kudar, Nina Kopylova, Danila Guzenkov, Darya Petrachkova, Andrey Mamontov, Andrey Trullioff, Irina Kiseleva   +10 more
doaj   +1 more source

Detection of neuraminidase inhibitor-resistant influenza A (H1N1)pdm09 viruses obtained from influenza surveillance in Indonesia

SAGE Open Medicine, 2018
Background: Influenza antiviral resistance has been shown to occur in many countries and is commonly found in influenza A(H1N1)pdm09 and A(H3N2). In this study, we monitored and investigated the neuraminidase inhibitor resistance of influenza A(H1N1 ...
Hana Apsari Pawestri, Arie Ardiansyah Nugraha, Nur Ika Hariastuti, Vivi Setiawaty   +3 more
doaj   +1 more source

Evolutionary analysis of influenza A(H1N1)pdm09 during the pandemic and post-pandemic period in Pakistan

Journal of Infection and Public Health, 2020
Background: The first case of influenza A(H1N1)pdm09 was detected in Pakistan in June 2009. Since then, it has continued to circulate causing considerable morbidity and mortality.
Nazish Badar, Muhammad Salman, Uzma B. Aamir, Jamil Ansari, Muazam A. Ranjha, Mumtaz A. Khan, Aamer Ikram, Nadia Nisar, Nighat Mushtaq, Hamza A. Mirza   +9 more
doaj   +1 more source

A Sequence‐Based Update on Amino Acid Substitutions in Influenza Polymerase Acidic Protein in Europe That Alter Baloxavir Susceptibility From 2009 to 2025

Influenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.
ABSTRACT Background Influenza causes 650,000 deaths, 3–5 million hospitalizations, and 1 billion cases worldwide each year. There is a limited repertoire of antivirals available to tackle this burden, highlighting the risk of developing resistance to current drugs.
Alejandro Martín‐Toribio, Inés Inchausti‐Moya, Marina Toquero‐Asensio, Sonia García‐Díaz, Javier Sanchez‐Martinez, Carla Rodriguez‐Crespo, Silvia Galindo‐Carretero, Raquel Iglesia‐Aparicio, Celia Lopez‐Gonzalo, Ana Antón‐Contreras, Silvia Rojo‐Rello, Marta Dominguez‐Gil, Marta Hernández, Jose M. Eiros, Estanislao Nistal‐Villan, Iván Sanz‐Muñoz   +15 more
wiley   +1 more source

A phylogenetic tree of A(H1N1) pdm09 nucleotide sequences.

, 2013
A phylogenetic tree of A(H1N1) pdm09 nucleotide sequences.
Jennifer Espiritu (432670), Peter Sebeny (432665), Margaret Farrell (432664), John Zumwalt (432671), Mark Turner (432668), John D. Klena (194511), Antony Joseph (432669), Cecilia DeMattos (432666), Guillermo Pimentel (432667), Erica Dueger (432672)   +9 more
core   +1 more source

Did the H1N1 Vaccine Reduce the Risk of Admission with Influenza and Pneumonia during the Pandemic? [PDF]

PLoS ONE, 2015
The extent to which A(H1N1)pdm09 influenza vaccines prevented hospital admissions with pneumonia and influenza (P&I) during the 2009 pandemic remains poorly understood.
Salaheddin M Mahmud, Songul Bozat-Emre, Gregory Hammond, Lawrence Elliott, Paul Van Caeseele   +4 more
doaj   +1 more source

Enhanced Human Antigen‐Specific B Cell Responses Using In Vitro 3D Tonsil Cultures Containing Stromal Cells

Advanced Healthcare Materials, Volume 15, Issue 22, 12 June 2026.
We developed a fully human 3D tonsil cell culture system incorporating supportive stromal cells that better sustains and activates immune cells than conventional methods. The model generates stronger, more targeted antibody responses to viral antigens and vaccines, providing a physiologically relevant and entirely human platform for studying immune ...
Maaike V. J. Braham, Marlon de Gast, Liubov Babii, Sabine Kruijer, Theo M. Bestebroer, Mathilde Richard, Mathieu Claireaux, S. Marieke van Ham, Jelle de Wit, Cécile A. C. M. van Els, Anja ten Brinke, Marit J. van Gils   +11 more
wiley   +1 more source

Coinfection with influenza A(H1N1)pdm09 and dengue virus in fatal cases [PDF]

Memórias do Instituto Oswaldo Cruz, 2016
We report on four patients with fatal influenza A(H1N1)pdm09 and dengue virus coinfections. Clinical, necropsy and histopathologic findings presented in all cases were characteristic of influenza-dengue coinfections, and all were laboratory-confirmed for both infections.
Perdigão, Anne Carolinne Bezerra, Ramalho, Izabel Letícia Cavalcante, Guedes, Maria Izabel Florindo, Braga, Deborah Nunes Melo, Cavalcanti, Luciano Pamplona Góes, Melo, Maria Elisabeth Lisboa de, Araújo, Rafael Montenegro de Carvalho, Lima, Elza Gadelha, Silva, Luciene Alexandre Bié da, Araújo, Lia de Carvalho, Araújo, Fernanda Montenegro de Carvalho   +10 more
openaire   +4 more sources

Preliminary analysis of influenza A(H1N1)v individual and aggregated case reports from EU and EFTA countries [PDF]

, 2009
Since the first importation of influenza A(H1N1)v virus to Europe in late April of this year, surveillance data have been collected in the Member States of the European Union and European Free Trade Association.
Gauci, Charmaine, ECDC working group on influenza A(H1N1)v   +1 more
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