Results 31 to 40 of about 30,764 (208)

Seasonal influenza vaccination expands hemagglutinin-specific antibody breadth to older and future A/H3N2 viruses

npj Vaccines, 2022
History of influenza A/H3N2 exposure, especially childhood infection, shape antibody responses after influenza vaccination and infection, but have not been extensively studied.
Nina Urke Ertesvåg, Rebecca Jane Cox, Sarah Larteley Lartey, Kristin G-I Mohn, Karl Albert Brokstad, Mai-Chi Trieu   +5 more
doaj   +1 more source

Influenza vaccine effectiveness from nine studies during drifted A(H3N2) subclade K predominance, Europe, September 2025 to January 2026. [PDF]

Euro Surveill
Lucaccioni H, Marques DF, Kirsebom F, Emborg HD, Hamilton M, Whitaker H, Bolt Botnen A, Bucholc M, Pozo F, Andrews N, Trebbien R, Hameed SS, Lauenborg Møller K, O'Doherty MG, Lopez-Bernal J, Morrison K, Cottrell S, Wilton S, Rose AM, Kissling E, European IVE group.   +20 more
europepmc   +2 more sources

H3N2 avian influenza viruses detected in live poultry markets in China bind to human-type receptors and transmit in guinea pigs and ferrets

Emerging Microbes and Infections, 2019
The H3N2 influenza viruses became widespread in humans during the 1968 H3N2 pandemic and have been a major cause of influenza epidemics ever since. Different lineages of H3N2 influenza viruses are also commonly found in animals. If a different lineage of
Lizheng Guan, Jianzhong Shi, Xingtian Kong, Shujie Ma, Yaping Zhang, Xin Yin, Xijun He, Liling Liu, Yasuo Suzuki, Chengjun Li, Guohua Deng, Hualan Chen   +11 more
doaj   +1 more source

Highly Cross-Reactive and Protective Influenza A Virus H3N2 Hemagglutinin- and Neuraminidase-Specific Human Monoclonal Antibodies

Microbiology Spectrum, 2023
Due to antigenic drift and shift of influenza A viruses (IAV) and the tendency to elicit predominantly strain-specific antibodies, humanity remains susceptible to new strains of seasonal IAV and is at risk from viruses with pandemic potential for which ...
Michael Piepenbrink, Fatai Oladunni, Aitor Nogales, Ahmed M. Khalil, Theresa Fitzgerald, Madhubanti Basu, Christopher Fucile, David J. Topham, Alexander F. Rosenberg, Luis Martinez-Sobrido, James J. Kobie   +10 more
doaj   +1 more source

A Real‐Time Antifouling Multivalent Aptamer Platform for Wash‐Free Electrochemical Detection of Low‐Abundance Biomarkers in Human Plasma

Angewandte Chemie, EarlyView.
Detection of low‐abundance proteins at the point‐of‐care is key for early detection and real‐time monitoring. The clinical translation of such assays is hindered by biofouling, matrix variability, and signal instability. RT‐MagMAp assay overcomes these challenges and enables precise protein quantification in human plasma using a hierarchical assembly ...
Payel Sen, Survanshu Saxena, Zijie Zhang, Navreen Sandhu, Pranati Das, Jimmy Gu, Todd Hoare, Yingfu Li, Leyla Soleymani   +8 more
wiley   +2 more sources

A Characterization and an Evolutionary and a Pathogenicity Analysis of Reassortment H3N2 Avian Influenza Virus in South China in 2019–2020

Viruses, 2022
Seasonal H3N2 influenza virus has always been a potential threat to public health. The reassortment of the human and avian H3N2 influenza viruses has resulted in major influenza outbreaks, which have seriously damaged human life and health. To assess the
Tengfei Liu, Yuhao Huang, Shumin Xie, Lingyu Xu, Junhong Chen, Wenbao Qi, Ming Liao, Weixin Jia   +7 more
doaj   +1 more source

Spread of Canine Influenza A(H3N2) Virus, United States [PDF]

Emerging Infectious Diseases, 2017
A canine influenza A(H3N2) virus emerged in the United States in February-March 2015, causing respiratory disease in dogs. The virus had previously been circulating among dogs in Asia, where it originated through the transfer of an avian-origin influenza virus around 2005 and continues to circulate.
Ian E.H. Voorhees, Amy L. Glaser, Kathy L. Toohey-Kurth, Sandra Newbury, Benjamin D. Dalziel, Edward Dubovi, Keith Poulsen, Christian Leutenegger, Katriina J.E. Willgert, Laura Brisbane-Cohen, Jill Richardson-Lopez, Edward C. Holmes, Colin R. Parrish   +12 more
openaire   +3 more sources

Predicting Antigenic Variants of Influenza A/H3N2 Viruses

Emerging Infectious Diseases, 2004
Current inactivated influenza vaccines provide protection when vaccine antigens and circulating viruses share a high degree of similarity in hemagglutinin protein. Five antigenic sites in the hemagglutinin protein have been proposed, and 131 amino acid positions have been identified in the five antigenic sites.
Min-Shi Lee, Jack Si-En Chen
openaire   +3 more sources

A statistical analysis of antigenic similarity among influenza A (H3N2) viruses [PDF]

Heliyon, 2021
An accurate assessment of antigenic similarity between influenza viruses is important for vaccine strain recommendations and influenza surveillance. Due to the mechanisms that result in frequent changes in the antigenicities of strains, it is desirable to obtain an antigenic similarity measure that accounts for specific changes in strains that are of ...
openaire   +3 more sources

Molecular identification of neuraminidase gene mutations in influenza A/H1N1 and A/H3N2 isolates of Mazandaran province, north of Iran

Journal of Global Antimicrobial Resistance
Objectives: The neuraminidase (NA) mutations causing resistance to NA inhibitors (NAIs) mostly compromise the fitness of influenza viruses. Considering the importance of these mutations, constant monitoring of the effectiveness of available drugs is ...
Mehdi Rabie-Rudsari, Emad Behboudi, Ategheh Ranjkesh, Kimia Kaveh, Hadi Razavi-Nikoo, Mohammad Reza Haghshenas, Abdolvahab Moradi   +6 more
doaj   +1 more source