Results 1 to 10 of about 25,196 (175)

Comparison of Clinical Outcomes of Two Different Cardioplegic Solutions in Patients Undergoing Coronary Artery Bypass Graft Surgery; A randomize clinical trial [PDF]

Advanced Biomedical Research
Background: Usually, manual cardioplegic solutions with low magnesium and lidocaine, and corporate solutions with high magnesium and procaine, are the only common solutions used to induce cardiac arrest during coronary artery bypass graft (CABG) surgery.
Alireza Hosseini, Mehran Shahzamani, Asieh Maghami-Mehr, Farzin Khosravi, Nafiseh Emadi   +4 more
doaj   +2 more sources

The effect of the design of the irrigation needle used during endodontic treatment on postoperative pain: a randomize clinical trial [PDF]

Scientific Reports
The aim of this study is to evaluate the effect of irrigation needles with different designs on postoperative pain during endodontic treatment. This randomized clinical study was conducted on 66 patients with symptomatic irreversible pulpitis of the ...
Ayça Yersel, Damla Kırıcı
doaj   +2 more sources

Effect of pioglitazone therapy on high sensitive C-reactive protein and lipid profile in diabetic patients with renal transplantation; a randomize clinical trial [PDF]

Journal of Nephropathology, 2015
Background: Inflammation has a major role in disease lead to renal failure and diabetes mellitus, controlling inflammation in diabetic kidney receivers could decrease morbidity and mortality. Objectives: This study designed for evaluating the efficacy of
Rana Arashnia, Kobra Roohi-Gilani, Hamidreza Karimi-Sari, Niloofar Nikjoo, Ali Bahramifar   +4 more
doaj   +2 more sources

The Effect of Virtual Reality on Pain in Primiparity Women during Episiotomy Repair: A Randomize Clinical Trial [PDF]

Iranian Journal of Medical Sciences, 2015
Background: Pain is one of the side effects of episiotomy. The virtual reality (VR) is a non-pharmacological method for pain relief. The purpose of this study was to determine the effect of using video glasses on pain reduction in primiparity women ...
Nahid JahaniShoorab, Samira Ebrahimzadeh Zagami, Ali Nahvi, Seyed Reza Mazluom, Nahid Golmakani, Mahdi Talebi, Ferial Pabarja   +6 more
doaj   +1 more source

Effect of Folic Acid Supplementation in Pregnancy on Preeclampsia: The Folic Acid Clinical Trial Study [PDF]

Journal of Pregnancy, 2013
Preeclampsia (PE) is hypertension with proteinuria that develops during pregnancy and affects at least 5% of pregnancies. The Effect of Folic Acid Supplementation in Pregnancy on Preeclampsia: the Folic Acid Clinical Trial (FACT) aims to recruit 3,656 ...
Shi Wu Wen, Josee Champagne, Ruth Rennicks White, Doug Coyle, William Fraser, Graeme Smith, Dean Fergusson, Mark C. Walker   +7 more
doaj   +5 more sources

A Pragmatic Trial Evaluating the Impact of the Anumana Clinical Decision Support Tool for Guideline-Directed Management of Heart Failure (ACT-HF): Clinical trial design and methods [PDF]

American Heart Journal Plus
Background: Heart failure with reduced ejection fraction (HFrEF) is progressive and pervasive. Guidelines provide evidence-based recommendations to manage HFrEF, yet adherence to Guideline Directed Medical Therapy (GDMT) is low.
Francisco Lopez-Jimenez, Heather M. Alger, Sarah P. Hackett, Vinay Gundurao, Ketan Mehta, Prerak Jain, Praveen Kumar-M, Chinmay Padhye, Arjun Puranik, Kitzner Vassor, Sunil Kumar Ravi, Barbara Barry, Ranee Chatterjee, Chen Chow, Rowena Dolor, Stephen J. Greene, Grace Lin, David Rushlow, Mark Stampehl, Xuan Zhu, Samir Awasthi   +20 more
doaj   +2 more sources

A roadmap to using randomization in clinical trials [PDF]

BMC Medical Research Methodology, 2021
Abstract Background: Randomization is the foundation of any clinical trial involving treatment comparison. It helps mitigate selection bias, promotes similarity of treatment groups with respect to important known and unknown confounders, and contributes to the validity of statistical tests.
Vance W. Berger, Louis Joseph Bour, Kerstine Carter, Jonathan J. Chipman, Colin C. Everett, Nicole Heussen, Catherine Hewitt, Ralf-Dieter Hilgers, Yuqun Abigail Luo, Jone Renteria, Yevgen Ryeznik, Oleksandr Sverdlov, Diane Uschner, Robert A Beckman   +13 more
openaire   +11 more sources

Review of precision cancer medicine: Evolution of the treatment paradigm. [PDF]

, 2020
In recent years, biotechnological breakthroughs have led to identification of complex and unique biologic features associated with carcinogenesis. Tumor and cell-free DNA profiling, immune markers, and proteomic and RNA analyses are used to identify ...
Fountzilas, Elena, Kurzrock, Razelle, Nikanjam, Mina, Tsimberidou, Apostolia M   +3 more
core   +1 more source

Methadone treatment of arrestees: A randomized clinical trial [PDF]

Drug and Alcohol Dependence, 2020
Opioid use disorder is common among detainees in US jails, yet methadone treatment is rarely initiated.This is a three-group randomized controlled trial in which 225 detainees in Baltimore treated for opioid withdrawal were assigned to: (1) interim methadone (IM) with patient navigation (IM + PN); (2) IM; or (3) enhanced treatment-as-usual (ETAU ...
R P, Schwartz, S M, Kelly, S G, Mitchell, K E, O'Grady, A, Sharma, J H, Jaffe   +5 more
openaire   +2 more sources

Design and rationale of a multi-center, pragmatic, open-label randomized trial of antimicrobial therapy - the study of clinical efficacy of antimicrobial therapy strategy using pragmatic design in Idiopathic Pulmonary Fibrosis (CleanUP-IPF) clinical trial [PDF]

, 2020
Compelling data have linked disease progression in patients with idiopathic pulmonary fibrosis (IPF) with lung dysbiosis and the resulting dysregulated local and systemic immune response.
A Mishra, AW Brown, B Ley, BA Karimi-Shah, BT Baxter, CJ Ryerson, DG Pankratz, DJ Lederer, G Raghu, G Raghu, H Scheper, HR Collard, J Andrade, J Coast, J Coast, K Loudon, K Loudon, KA Getz, KD Brandt, KE Thorpe, KF Schulz, L Richeldi, L Shulgina, LB Krupp, M Fralick, M Hammond, MA Fischl, MA Perazella, MO Paterniti, MT Durheim, P Bhattacharyya, PL Molyneaux, PL Molyneaux, PL Molyneaux, R Dal-Ré, RM Califf, RM du Bois, SD Nathan, SS Birring, T Katsuyama, TE King Jr, VA Varney, WS Jones, Y Huang   +43 more
core   +1 more source