Results 11 to 20 of about 25,315 (294)

Magnesium treatment in alcoholics: A randomized clinical trial [PDF]

Substance Abuse Treatment, Prevention, and Policy, 2008
Abstract Background Magnesium (Mg) deficiency is common among alcoholics. Earlier research suggests that Mg treatment may help to normalize elevated enzyme activities and some other clinically relevant parameters among alcoholics but the evidence is weak.
Poikolainen Kari, Alho Hannu
openaire   +4 more sources

Randomizing a clinical trial in neuro-degenerative disease

Contemporary Clinical Trials Communications, 2023
The paper studies randomization rules for a sequential two-treatment, two-site clinical trial in Parkinson's disease. An important feature is that we have values of responses and five potential prognostic factors from a sample of 144 patients similar to those to be enrolled in the trial. Analysis of this sample provides a model for trial analysis.
Anthony C. Atkinson, Belmiro P.M. Duarte, David J. Pedrosa, Marlena van Munster   +3 more
openaire   +4 more sources

Factors Influencing Surgical Decision-Making in the Posterior Laminectomy With Fixation for Degenerative Cervical Myelopathy (POLYFIX-DCM) Trial: Survey Study

JMIR Formative Research, 2023
BackgroundDegenerative cervical myelopathy (DCM) is estimated to affect 2% of the adult population. DCM occurs when degenerative processes cause compression and injure the spinal cord.
Stefan Yordanov, Xiaoyu Yang, Oliver Mowforth, Andreas K Demetriades, Marcel Ivanov, Pierluigi Vergara, Adrian Gardner, Erlick Pereira, Antony Bateman, Alexander Alamri, Jibin Francis, Rikin Trivedi, Mark Kotter, Benjamin Davies, Alexandru Budu   +14 more
doaj   +1 more source

Comparison of Mobilizing and Immobilizing Splints on Hand Motor Function in Stroke Patients: A Randomize Clinical Trial [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2011
Background and Objectives: Among several methods for the treatment of wrist-fingers motor function impairment after stroke, splinting is a method commonly used as complementary option. But there are so many controversies surrounding its efficacy. The aim
Rahimi Fard H, Hosseini A, Abutalebi Sh, Eqlidi J, Heydari M, Emadi Fard R, Safdari F   +6 more
doaj   +2 more sources

Developing and testing a Corona VaccinE tRiAL pLatform (COVERALL) to study Covid-19 vaccine response in immunocompromised patients

BMC Infectious Diseases, 2022
Background The rapid course of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic calls for fast implementation of clinical trials to assess the effects of new treatment and prophylactic interventions.
Katharina Kusejko, Frédérique Chammartin, Daniel Smith, Marc Odermatt, Julian Schuhmacher, Michael Koller, Huldrych F. Günthard, Matthias Briel, Heiner C. Bucher, Benjamin Speich, the Swiss HIV Cohort Study, Swiss Transplant Cohort Study   +11 more
doaj   +1 more source

A Bayesian adaptive marker‐stratified design for molecularly targeted agents with customized hierarchical modeling [PDF]

, 2019
It is well known that the treatment effect of a molecularly targeted agent (MTA) may vary dramatically, depending on each patient's biomarker profile. Therefore, for a clinical trial evaluating MTA, it is more reasonable to evaluate its treatment effect ...
Cao, Sha, Guo, Beibei, Han, Yan, Zang, Yong, Zhang, Chi   +4 more
core   +3 more sources

Evaluation of Efficiency of 25% Oral Sucrose on Pain Reduction due to Hepatitis B Vaccination in Newborns: A Randomize Clinical Trial [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2010
Background and Objectives: The ability of neonates to perceive and react to pain has recently been acknowledged. Sweet solutions are one of the recommendations for pain relief in newborns.
Saadati H, Fakehi F, Sangsefedi Z, Mirzarahimi M, Mohammadzadeh A, Saeedi R   +5 more
doaj   +2 more sources

A fresh look at paralytics in the critically ill: real promise and real concern. [PDF]

, 2012
Neuromuscular blocking agents (NMBAs), or "paralytics," often are deployed in the sickest patients in the intensive care unit (ICU) when usual care fails.
Kenyon, Nicholas J, Price, David, Stollenwerk, Nicholas   +2 more
core   +2 more sources

The Effect of Chewing Sugar Free Gum after Elective Cesarean-Delivery on Return of Bowel Function in Primiparous Women [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2011
Background and Objectives: An important cause of delayed recovery from abdominal surgery is delay in return of bowel Function. The aim of the present study was to assess the effects of chewing sugar free gum after elective Cesarean-delivery on return of ...
F Safdari Dehcheshmeh, T Salehian, F Gangi, M Beigi   +3 more
doaj   +1 more source

The Effect of Acupressure at the 3rd Point of liver Channel on Quality of Life of Female Students with Primary Dysmenorrhea in Tehran Teacher Training Center in 2008: A Randomize Clinical Trial [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2010
Background and Objectives: Dysmenorrhea affects women’s quality of life; moreover it results in physical, mental, social and economical problems. The aim of this study was to evaluate the effect of acupressure at the third point of liver channel (liv3 ...
Taghavi A., Heshmat R., Lamyian M., Bazarganipour F., Faghihzadeh S.   +4 more
doaj   +2 more sources