Results 141 to 150 of about 131,610 (332)
652. Passive Immunization with an AAV Vector Expressing an Anti-Cocaine Antibody Shields the Brain from Systematically Administered Cocaine, Suppressing Cocaine-Induced Hyperlocomotion [PDF]
, 2011 openalex +1 more source
Advanced Science, EarlyView.Utilizing dual‐site fiber photometry, this study examines cortico‐striatal coupling with cell type resolution, identifying behavior‐ and cell type‐specific cortico striatal decoupling and its dopamine‐dependent mechanism in a Parkinson's disease mouse model.
Xu‐Ran Yao +4 more
wiley +1 more source
AAV6 Is Superior to Clade F AAVs in Stimulating Homologous Recombination-Based Genome Editing in Human HSPCs [PDF]
, 2019 Amanda M. Dudek, Matthew H. Porteus
openalex +1 more source
Advanced Science, EarlyView.Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan +11 more
wiley +1 more source
Convergent and Divergent Connectivity Patterns of the Arcuate Fasciculus in Macaques and Humans
Advanced Science, EarlyView.This study employs viral‐based single‐neuron tracing and dMRI‐based whole‐brain tractography to investigate arcuate fasciculus (AF) trajectories in macaque monkeys, and compares with the human AF connectome using spectral embedding. Results demonstrate conserved AF topography spanning temporoparietal‐auditory‐frontal pathways across primates, with ...
Jiahao Huang +17 more
wiley +1 more source
60. Site-Specific Integration in Human Somatic Cell DNA by Adeno/AAV Hybrid Vectors [PDF]
, 2004 openalex +1 more source
A Novel Enhancer-AAV Approach Selectively Targeting Dentate Granule Cells
, 2023 Emmie Banks +8 more
openalex +1 more source
Advanced Science, EarlyView.Here, the study shows for the first time that Forsythoside E (FE) can promote PKM2 tetramerization by binding to its K311 site. Furthermore, it induces metabolic reprogramming of macrophages and inhibits NLRP3 expression. Finally, it can alleviate sepsis‐induced liver injury by promoting M2 anti‐inflammatory polarization.
Bingxin Wu +8 more
wiley +1 more source