Protocol for efficient CRISPR/AAV-mediated genome editing and erythroid differentiation of human hematopoietic stem and progenitor cells. [PDF]
Sharma D, Sinha R, Lesch BJ, Cromer MK.
europepmc +1 more source
1105. Potent Inhibition of Neointima Formation by a Tissue Metalloprotease Inhibitor (Timp-1) Delivered through AAV Vectors [PDF]
openalex +1 more source
A novel hybrid gene delivery platform combines adeno‐associated virus (AAV)‐mediated receptor‐interacting kinase 3 (RIPK3) expression with manganese dioxide‐polyethyleneimine (MnO2−PEI) nanoshield to induce necroptosis, ferroptosis, and immunogenic cell death, effectively reprogramming the tumor microenvironment.
Soo‐Hwan Lee +8 more
wiley +1 more source
An adeno-associated virus gene therapy strategy for anti-obesity treatment by nanocarrier-based delivery systems. [PDF]
Li L +11 more
europepmc +1 more source
1193. Receptor-Targeted AAV Vector-Mediated Expression of HSV-TK Confers Selective Cytotoxicity to Human Ovarian Adenocarcinoma Cells [PDF]
openalex +1 more source
Hepatic CBP/p300 Orchestrate Amino Acid‐Driven Gluconeogenesis through Histone Crotonylation
Hepatic CBP/p300 control amino acid‐driven gluconeogenesis by modulating histone crotonylation. This study identifies 2‐aminoadipate (2‐AAA) as a key metabolite that enhances crotonylation and activates amino acid and gluconeogenic gene expression.
Chunxiang Sheng +15 more
wiley +1 more source
750. AAV Vector-Mediated Delivery of GDNF Gene into Muscles Protects Spinal Motoneurons and Improves Motor Performance in a Transgenic Mouse Model of ALS [PDF]
openalex +1 more source

