Results 241 to 250 of about 79,958 (292)

Indirect Striatal Projection Neurons Drive a D2 Receptor‐Dependent Pathway to Dyskinesia and Dystonia

Movement Disorders, EarlyView.
D2 receptor ablation in indirect‐pathway striatal neurons reduces or abolishes dyskinetic and dystonic behaviors induced by L‐DOPA or D2 receptor agonists, respectively. Contralateral turning is reduced, while forward locomotion is increased. These effects are associated with modulation of neuronal activity in dorsal striatum and external globus ...
Laura Andreoli, Teodor Nyman, Elena Espa, Johan Jakobsson, Osama F. Elabi, Maria Angela Cenci   +5 more
wiley   +1 more source

Anti-neutrophil Cytoplasmic Antibody-Associated Vasculitis Complicated by Subarachnoid Hemorrhage due to a Ruptured Cerebral Aneurysm: A Case Report. [PDF]

NMC Case Rep J
Tomita M, Kaneko J, Yamada S, Sato S, Kitahashi A, Kaneko T, Kuno M, Yokobori S.   +7 more
europepmc   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

Abca4 Knockdown in the Cone-Rich Rodent Psammomys Obesus Leads to Stargardt's Disease-Like Progressive Retinal Degeneration. [PDF]

Invest Ophthalmol Vis Sci
Estay-Ahumada CE, Roux M, Ciocca D, El-Kholti N, Birling MC, Rossolillo P, Felder-Schmittbuhl MP, Hicks D.   +7 more
europepmc   +1 more source

FTO-Catalysed Demethylation of LUR1 mRNA Suppresses Macrophage Lipid Accumulation and Aortic Atherosclerosis. [PDF]

J Cell Mol Med
Tang XY, Zhou L, Li SJ, Zhang SX, Yuan YY, Lv YC.   +5 more
europepmc   +1 more source

A multispecialty consensus-based red flag checklist for the early recognition of ANCA-associated vasculitis. [PDF]

Front Immunol
Quartuccio L, Alberici F, Cimino L, De Paulis A, Gelardi M, Massacesi L, Poletti V, Salvarani C, Iannone F.   +8 more
europepmc   +1 more source

Transient prophylactic immunosuppression with abatacept or dasatinib prevents immune responses in AAV gene transfer. [PDF]

Mol Ther
Xicluna R, Yamada K, Gonzalez-Visiedos M, Greenwood CM, Zaugg D, Waiz D, Steiner G, Hahn K, Schwandt T, Otteneder MB, Biswas M, Muñoz-Melero M, Kumar SRP, Herzog RW, Haegel H.   +14 more
europepmc   +1 more source

ANCA-associated vasculitis with thoracic spinal canal dural involvement and hypertrophic cranial pachymeningitis: A case report. [PDF]

Medicine (Baltimore)
Yin X, Zhou W.
europepmc   +1 more source