Results 291 to 300 of about 131,610 (332)

Comparison of three pediatric studies investigating acute hepatitis of unknown etiology. [PDF]

World J Virol
Komatsu H.
europepmc   +1 more source

Malignancy and gene therapy in hemophilia. [PDF]

Res Pract Thromb Haemost
Kaczmarek R.
europepmc   +1 more source

Neuronal Sik1 in the Hypothalamic Paraventricular Nucleus Decreases Blood pressure Elevation Following a High-Salt Diet. [PDF]

Mol Neurobiol
Zhang W, Wang P, Qi S, Huang N, Huang Q, Guo Z, Wu W, Tan G.   +7 more
europepmc   +1 more source

Isorhamnetin Alleviates Renal Fibrosis Induced by Renal Tubular Epithelial Cell Senescence Via Inhibition of the IL‐6/IL‐6R Signaling Pathway

iMetaMed, EarlyView.
IL‐6 from RTECs upregulates TGF‐β in macrophages, promoting fibroblast transdifferentiation. Isorhamnetin inhibits this effect. ABSTRACT Chronic kidney disease (CKD) is a major global health issue. Kidney fibrosis is a key mechanism leading to end‐stage renal disease.
Weifei Liang, Xiangqiu Chen, Tao Wu, Xichun Zheng, Shaohua Zeng, Qingchun Zhou, Wen Ma, Hao Lin, Donglin Sun   +8 more
wiley   +1 more source

LncRNA Wee1-AS coordinates oxidative fatty acid metabolism through the activation of mitochondrial CDK1/CYCLIN B1. [PDF]

Signal Transduct Target Ther
Kim HJ, Jeong C, Lee SH, An S, Hyun GH, Lim GY, Kim JY, Lee J, Park MJ, Kwon SW, Kim W, Noh M, Han YH, Lee MO.   +13 more
europepmc   +1 more source

GDNF signaling modulation by Akkermansia muciniphila ameliorates constipation-depression comorbidity in Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Mu C, Zhou Z, Li J, Su M, Xue K, Zhang J, Shi S, Li Y, Yao X, Wang M, Zhang W, Wang Z, Zhu J, Fang S, Wang W, Tang C, Qin X.   +16 more
europepmc   +1 more source

A novel vector design targeting the blood-brain barrier with the brain-specific AAV-BR1 vector enables abluminal protein secretion from brain endothelial cells in vitro. [PDF]

Fluids Barriers CNS
Laczek B, Thomsen MS, Körbelin J, Burkhart A, Moos T.   +4 more
europepmc   +1 more source

AAV-mediated gene therapy for the CNS: The case for early treatment. [PDF]

Mol Ther Methods Clin Dev
Liebscher Vidal LE, Martinez-Navio JM.
europepmc   +1 more source

Long-term stable intraocular pressure (IOP) control and optic nerve head (ONH) preservation following AAV-mediated ocular gene therapy in a canine model of ADAMTS10-open-angle glaucoma (OAG)

, 2019
András M. Komáromy, Kristin Koehl, Christine D. Harman, Sanford L. Boye, Juan P. Steibel, Leandro B. C. Teixeira, Carol B. Toris, Sayoko Eileen Moroi, Sanford L. Boye   +8 more
openalex   +1 more source