Results 101 to 110 of about 15,511 (169)
Spectrophotometric Estimation of Abacavir Sulphate in Pharmaceutical Formulations
E-Journal of Chemistry, 2008 Two simple, accurate, rapid and sensitive methods (A and B) have been developed for the estimation of abacavir sulphate in its pharmaceutical dosage form.
N. Appala Raju +3 more
doaj +1 more source
Two cases of occupational allergic contact dermatitis caused by abacavir
, 2019 Abacavir is a nucleoside analogue reverse transcriptase inhibitor that is used for the treatment of human immunodeficiency virus (HIV) infection. Drug hypersensitivity has been reported in up to 8% of patients.
Sharizan Ghaffar +3 more
core +1 more source
, 2014 Abacavir is a nucleoside reverse transcriptase inhibitor used in combination therapy for the treatment of the human immunodeficiency virus type 1 (HIV-1) that has been associated with a hypersensitivity reaction in approximately 8% of those starting the ...
Phillips, E.J., Mallal, S.
core
Oxidative Bioactivation of Abacavir in Subcellular Fractions of Human Antigen Presenting Cells
, 2016 Human exposure to abacavir, a primary alcohol antiretroviral, is associated with the development of immunological drug reactions in individuals carrying the HLA risk allele B*57:01.
B. Kevin Park (310370) +8 more
core +1 more source
, 2010 Abacavir is a guanosine analog that competitively inhibits the reverse transcriptase of the human immunodefiency virus (HIV) and is used in combination antiretroviral therapy for the treatment of HIV.
Mallal, S.A., Phillips, E.J.
core
Individualization of antiretroviral therapy [PDF]
, 2012 Antiretroviral therapy (ART) has evolved considerably over the last three decades. From the early days of monotherapy with high toxicities and pill burdens, through to larger pill burdens and more potent combination therapies, and finally, from 2005 and ...
Pavlos, R., Phillips, E.J.
core
, 2005 Background: The clinical treatment of patients with HIV and adverse drug events may be enhanced by an understanding of the underlying mechanisms. About 4% of patients with HIV receiving the potent antiretroviral drug abacavir develop a hypersensitivity ...
Raffi, F +8 more
core +1 more source
Updated experience of abacavir hypersensitivity genetic testing within the major histocompatibility complex (MHC): addressing diagnostic precision and predictive value [PDF]
, 2003 OBJECTIVES: To assess the predictive value (PV) of genetic testing for abacavir hypersensitivity syndrome (HSR) in the Western Australian HIV Cohort Study, and to extend genetic mapping of genetic susceptibility locus/loci.
Martin, A. +10 more
core
, 2018 Abacavir is a widely used nucleotide reverse transcriptase inhibitor, for which cerebrospinal fluid (CSF) exposure has been previously assessed in twice-daily recipients.
Pinnetti, C. +21 more
core +1 more source
Clinical and immunogenetic correlates of abacavir hypersensitivity
, 2005 A patch test (PT) may be useful in defining true abacavir hypersensitivity syndrome (AHS). Seven previously PT-positive patients remote from the original AHS were shown to have robust 24 h responses, supporting PT durability.
Martin, A.M. +8 more
core