Results 81 to 90 of about 15,511 (169)

The use of electrochemical oxidation in abacavir degradation studies [PDF]

, 2020
The focus of this bachelor's thesis is the electrochemical degradation of abacavir. Abacavir is the active pharmaceutical ingredient of the medicine for human immunodeficiency virus (HIV).
Pražáková, Lucie
core  

Incidence of abacavir hypersensitivity reactions in euroSIDA

, 2008
Udgivelsesdato: 2008-nullBACKGROUND: The aim of the study was to investigate the incidence of abacavir-related hypersensitivity reaction (HSR) and associated deaths in EuroSIDA HIV-1-infected patients. METHODS: Poisson regression models were developed to
Bánhegyi, Dénes, Bannister, Wendy P, Friis-Møller, Nina, Mocroft, Amanda, Gargalianos, Panagiotis, van Lunzen, Jan, Viard, Jean-Paul, Kirk, Ole, Lundgren, Jens, Chiesi, Antonio   +9 more
core   +1 more source

Early changes in inflammatory and pro-thrombotic biomarkers in patients initiating antiretroviral therapy with abacavir or tenofovir

BMC Infectious Diseases, 2011
Background Abacavir has been associated with an increased risk of acute myocardial infarction, but the pathogenic mechanisms remain unknown. We evaluated longitudinal changes in pro-atherosclerotic biomarkers in patients initiating abacavir or tenofovir.
Tormo Consuelo, Jarrin Inmaculada, García Natalia, Masiá Mar, Padilla Authors:, Gutiérrez Félix   +5 more
doaj   +1 more source

A multicentre evaluation of cardiovascular risk prediction tools in people living with HIV across England (ECARTH study)

HIV Medicine, Volume 27, Issue 10, Page 1629-1641, October 2026.
Abstract Introduction It remains unclear which cardiovascular disease (CVD) risk scores are optimized for people living with treated HIV with high rates of viral suppression. We evaluated the performance of commonly used CVD risk scores in a population of primarily well‐treated HIV patients in England.
Ming Jie Lee, Ashley Murray, Colette Smith, Zakee Abdi, Alastair Duncan, Ellen Dwyer, Mark Gompels, Merle Henderson, Margaret Johnson, Frances Lander, Gavin Manmathan, Jonathan Mok, Nnenna Ngwu, Coral Pratt, Iain Reeves, Razan Saman, Alice Sharp, Eleanor Taylor, Jhia Jiat Teh, Richard Stevens, Thomas R. Fanshawe, Jienchi Dorward, Ranjababu Kulasegaram, Anthony S. Wierzbicki   +23 more
wiley   +1 more source

Synthesis and sensing properties of a new carbazole fluorosensor for detection of abacavir

, 2010
An abacavir-targeted fluorosensor based on the carbazole moiety has been synthesised and characterised. Recognition of abacavir is by base pairing between a uracil moiety present in the fluorosensor and the guanine moiety of abacavir.
Mohr, GJ, Cranfield, Charles G., Cranfield, CG, Gerhard J. Mohr, Idzik, KR, Krzysztof R. Idzik, Beckert, Rainer, Beckert, R, Charles G. Cranfield, Cywinski, PJ, Idzik, Krzysztof R., Piotr J. Cywinski, Rainer Beckert, Cywinski, Piotr J., Mohr, Gerhard J., Idzik, K.R., Cranfield, C.G., Cywinski, P.J., Beckert, R., Mohr, G.J.   +19 more
core   +2 more sources

HLA-B*57:01 screening and hypersensitivity reaction to abacavir between 1999 and 2016 in the OPERA® observational database: a cohort study

AIDS Research and Therapy, 2019
Background HLA-B*57:01 screening was added to clinical care guidelines in 2008 to reduce the risk of hypersensitivity reaction from abacavir. The uptake of HLA-B*57:01 screening and incidence of hypersensitivity reaction were assessed in a prospective ...
Karam Mounzer, Ricky Hsu, Jennifer S. Fusco, Laurence Brunet, Cassidy E. Henegar, Vani Vannappagari, Chris M. Stainsby, Mark S. Shaefer, Leigh Ragone, Gregory P. Fusco   +9 more
doaj   +1 more source

Characteristics and management of low‐level viraemia in people living with HIV in a resource‐limited setting: A multicentre retrospective study in Greece

HIV Medicine, Volume 27, Issue 10, Page 1663-1669, October 2026.
Abstract Objectives Low‐level viraemia (LLV) persists in some people living with HIV despite antiretroviral therapy, raising concerns about virologic failure. We assessed the characteristics, management and outcomes of LLV in Greece, where next‐generation sequencing, therapeutic drug monitoring and electronic adherence monitoring are unavailable ...
Lydia Leonidou, Giota Lourida, Konstantinos Protopapas, Charalampos D. Moschopoulos, Dimitrios Zoulas, Charisis Totsikas, Dimitrios Basoulis, Elpida Mastrogianni, Apostolos Beloukas, Maria Lagadinou, Markos Marangos, Vasileios Papastamopoulos, Antonios Papadopoulos, Mina Psichogiou   +13 more
wiley   +1 more source

Frailty and associated clinical factors among Japanese people with HIV: A multicentre cross‐sectional study using the revised Japanese Cardiovascular Health Study criteria

HIV Medicine, Volume 27, Issue 10, Page 1670-1681, October 2026.
Abstract Objectives Frailty is relevant to HIV care across middle and later life, yet Japanese data remain limited. We evaluated frailty, prefrailty and associated factors in Japanese people with HIV using the revised Japanese Cardiovascular Health Study (J‐CHS) criteria.
Hideta Nakamura, Julian Falutz, Taro Naka, Sho Miyamori, Nanae Ikemiyagi, Kazutaka Yamaniha, Shuhei Ideguchi, Rumi Minami, Masashi Narita, Michinori Shirano, Sei Samukawa, Tomoyuki Endo, Junji Imamura, Mayumi Imahashi, Shinichiro Ueda, Kazuko Yamamoto   +15 more
wiley   +1 more source

Oxidative degradation study of abacavir

, 2020
The aim of this study is forced oxidative degradation of active pharmaceutical ingredient abacavir, used to treat HIV-infected patients. A fast and sensitive method for the determination of abacavir and its degradation products by ultra-high performance ...
Šušová, Nikola
core  

Cost impact of prospective HLA-B*5701-screening prior to abacavir/lamivudine fixed dose combination use in Germany

European Journal of Medical Research, 2010
Objective Avoiding abacavir in HIV-infected patients tested positive for HLA-B*5701 reduces the risk of abacavir hypersensitivity reaction (ABC-HSR). Our aim was to assess the costs of clinically suspected HSR and to estimate potential cost savings of ...
Wolf E, Blankenburg M, Bogner JR, Becker W, Gorriahn D, Mueller MC, Jaeger H, Welte R, Baudewig M, Walli R, Stoll M   +10 more
doaj   +1 more source