Results 11 to 20 of about 26,674 (238)

Benefits of Autoantibody Enrichment in Early Rheumatoid Arthritis: Analysis of Efficacy Outcomes in Four Pooled Abatacept Trials

Rheumatology and Therapy, 2023
Introduction The efficacy of abatacept is enhanced in anti-citrullinated protein antibody (ACPA) and rheumatoid factor (RF)-positive versus -negative patients with rheumatoid arthritis (RA).
Kaleb Michaud, Philip G. Conaghan, Sang Hee Park, Karissa Lozenski, Mirko Fillbrunn, Vadim Khaychuk, Elyse Swallow, John Vaile, Henry Lane, Ha Nguyen, Janet Pope   +10 more
doaj   +2 more sources

Effect of abatacept versus conventional synthetic disease modifying anti-rheumatic drugs on rheumatoid arthritis-associated interstitial lung disease [PDF]

The Korean Journal of Internal Medicine
Background/Aims To compare the effects of abatacept and conventional synthetic disease modifying anti-rheumatic drugs (csDMARDs) on the progression and development of rheumatoid arthritis-associated interstitial lung disease (RA-ILD).
Kyung-Ann Lee, Bo Young Kim, Sung Soo Kim, Yun Hong Cheon, Sang-Il Lee, Sang-Hyon Kim, Jae Hyun Jung, Geun-Tae Kim, Jin-Wuk Hur, Myeung-Su Lee, Yun Sung Kim, Seung-Jae Hong, Suyeon Park, Hyun-Sook Kim   +13 more
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Tocilizumab and Abatacept for the Treatment of Childhood Chronic Uveitis: A Monocentric Comparison Experience

Frontiers in Pediatrics, 2022
BackgroundOur study aimed to evaluate the efficacy of Tocilizumab and Abatacept for treating Childhood Chronic non-infectious Uveitis (CCU), resistant to anti-tumor necrosis factor (anti-TNF) treatment.MethodsThis is a monocentric retrospective charts ...
Ilaria Maccora, Ilaria Maccora, Sarah Abu Rumeileh, Franco Curci, Cinzia de Libero, Edoardo Marrani, Maria Vincenza Mastrolia, Ilaria Pagnini, Gabriele Simonini, Gabriele Simonini   +9 more
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Comparative effectiveness of abatacept versus TNF inhibitors in rheumatoid arthritis patients who are ACPA and shared epitope positive

Advances in Rheumatology
Background The HLA-DRB1 shared epitope (SE) is a risk factor for the development of rheumatoid arthritis (RA) and the production of anti-citrullinated protein antibodies (ACPAs) in RA patients. Our objective was to examine the real-world effectiveness of
Leslie R. Harrold, Keith Wittstock, Sheila Kelly, Xue Han, Joe Zhuo, Amy Schrader, Nicole Middaugh, Page C. Moore, Vadim Khaychuk   +8 more
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Safety and Effectiveness of Abatacept in a Prospective Cohort of Patients with Rheumatoid Arthritis–Associated Interstitial Lung Disease

Biomedicines, 2022
Objective: To prospectively evaluate the safety and efficacy profile of abatacept in patients with rheumatoid arthritis–associated interstitial lung disease (RA-ILD).
Natalia Mena-Vázquez, Marta Rojas-Gimenez, Clara Fuego-Varela, Aimara García-Studer, Nair Perez-Gómez, Carmen María Romero-Barco, Francisco Javier Godoy-Navarrete, Sara Manrique-Arija, Myriam Gandía-Martínez, Jerusalem Calvo-Gutiérrez, Pilar Morales-Garrido, Coral Mouriño-Rodriguez, Patricia Castro-Pérez, Isabel Añón-Oñate, Francisco Espildora, María Carmen Aguilar-Hurtado, Ana Hidalgo Conde, Rocío Arnedo Díez de los Ríos, Eva Cabrera César, Rocío Redondo-Rodriguez, María Luisa Velloso-Feijoo, Antonio Fernández-Nebro   +21 more
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Association of HLA-DRB1 locus with treatment response to abatacept or TNF inhibitors in patients with seropositive rheumatoid arthritis

Scientific Reports
The strongest genetic risk factor for rheumatoid arthritis (RA) has been known as HLA-DRB1 based on amino acid positions 11, 71, and 74. This study analyzed the association between specific HLA-DRB1 locus and treatment response to abatacept or TNF ...
Soojin Cha, So-Young Bang, Young Bin Joo, Soo-Kyung Cho, Chan-Bum Choi, Yoon-Kyoung Sung, Tae-Hwan Kim, Jae-Bum Jun, Dae Hyun Yoo, Hye-Soon Lee, Sang-Cheol Bae   +10 more
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Real-world clinical outcomes and rationale for initiating abatacept as a first-line biologic for patients with anticitrullinated protein antibody- and rheumatoid factor-positive rheumatoid arthritis

Journal of Comparative Effectiveness Research
Aim: In rheumatoid arthritis (RA), seropositivity for both anticitrullinated protein antibody (ACPA) and rheumatoid factor (RF) is associated with disease severity and therapeutic response.
Alexandrina Balanean, Cherrishe Brown-Bickerstaff, Andrew Klink, Vardhaman Patel, Hanke Zheng, Laetitia N’Dri, Keith Wittstock, Bruce Feinberg, Mark Chaballa, Vadim Khaychuk, Jill Kaufman, Prathamesh Pathak, Gordon Lam   +12 more
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Abatacept/Ruxolitinib and Screening for Concomitant Respiratory Muscle Failure to Mitigate Fatality of Immune-Checkpoint Inhibitor Myocarditis.

Cancer Discovery, 2023
Immune-checkpoint-inhibitor (ICI)-associated myotoxicity involves the heart (myocarditis) and skeletal muscles (myositis), which frequently occur concurrently and is highly fatal.
J. Salem, M. Bretagne, B. Abbar, S. Leonard-Louis, S. Ederhy, alban redheuil, Samia Boussouar, L. Nguyen, Adrien Procureur, Frederic Stein, C. Fenioux, Perrine Devos, P. Gougis, M. Dres, A. Demoule, D. Psimaras, T. Lenglet, T. Maisonobe, M. Pineton de Chambrun, G. Hékimian, C. Straus, J. Gonzalez-Bermejo, D. Klatzmann, A. Rigolet, P. Guillaume-Jugnot, N. Champtiaux, O. Benveniste, N. Weiss, S. Saheb, P. Rouvier, I. Plu, E. Gandjbakhch, M. Kerneis, N. Hammoudi, N. Zahr, C. Llontop, C. Morélot-Panzini, L. Lehmann, Juan Qin, J. Moslehi, M. Rosenzwajg, T. Similowski, Y. Allenbach   +42 more
semanticscholar   +1 more source

Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial

Diabetes Care, 2023
OBJECTIVE Previous studies showed that inhibiting lymphocyte costimulation reduces declining β-cell function in individuals newly diagnosed with type 1 diabetes.
W. Russell, B. Bundy, Mark S. Anderson, L. Cooney, S. Gitelman, R. Goland, P. Gottlieb, C. Greenbaum, M. Haller, J. Krischer, I. Libman, P. Linsley, S. A. Long, Sandra Lord, Daniel J. Moore, W. Moore, A. Moran, Andrew B. Muir, P. Raskin, J. Skyler, J. Wentworth, D. Wherrett, Darrell M. Wilson, A. Ziegler, K. Herold   +24 more
semanticscholar   +1 more source

Abatacept, Cenicriviroc, or Infliximab for Treatment of Adults Hospitalized With COVID-19 Pneumonia: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2023
Importance Immune dysregulation contributes to poorer outcomes in COVID-19. Objective To investigate whether abatacept, cenicriviroc, or infliximab provides benefit when added to standard care for COVID-19 pneumonia.
Jane A. O’Halloran, E. Ko, K. Anstrom, E. Kedar, M. McCarthy, R. Panettieri, M. Maillo, Patricia Segura Nunez, A. Lachiewicz, C. González, P. Smith, Sabina Mendivil-Tuchia de Tai, Akram Khan, A. Lora, M. Salathe, G. Capo, Daniel Rodríguez Gonzalez, T. Patterson, C. Palma, H. Ariza, M. P. Lima, J. Blamoun, E. Nannini, E. Sprinz, A. Mykietiuk, R. Alicic, A. Rauseo, C. Wolfe, B. Witting, Jennifer P. Wang, Luis Parra-Rodriguez, Tatyana Der, Kate Willsey, J. Wen, A. Silverstein, S. M. O’Brien, H. Al-Khalidi, M. Maldonado, R. Melsheimer, W. G. Ferguson, S. McNulty, P. Zakroysky, S. Halabi, D. Benjamin, S. Butler, J. Atkinson, S. Adam, So-youn Chang, L. LaVange, M. Proschan, S. Bozzette, W. Powderly, M. Patel, A. Sanyal, Jason Green, Huimin Wu, Benjamin Linas, Philip Grant, Vivek Iyer, Otto Yang, Bindu Balani, S. Parnia, R. Dare, C. Morse, E. Harris, G. Wortmann, Nicholas Hill, Shama Patel, J. Garcia-Diaz, Suman Thapamager, Megan Devine, C. Bojanowski, B. Meisenberg, Gailen D. Marshall, D. Dandachi, A. Sabin, Anthony Breemo, Suman Sinha, Chris Goss, Rebecca Reece, A. Aouad, Seth Glassman, P. Morris, B. Patel, F. Bello, Juliana Cardozo Fernandes, Oscar Carbajal, L. Ravera, Mozar Castro, Miguel Villegas-Chiroque, Fernando Oscar Riera, Adrian Camacho, C. Stadñik, Jorge Gave, Rodrigo Biondi, Ronal Gamarra Velarde, José Cerbino Neto, J. Ditondo, M. Losso, M. Dolz, Alexandra O’Sullivan, Brian Gavin, M. Beumont‐Mauviel, Huyen Ca, Rose Beci, Daniel Molina, Sandhya Rao, Thomas Stock, W. Erhardt, S. Read, J. Springer, R. Presti, Ryley M. Thompson, Kimberlyn Gray, Cat Henry, Alem Haile, Michael Klebert, L. Kessels, K. Vehe, K. Bakos, T. Spitz, S. Hubert, Raghd Alyatim, B. Schneider, Chapelle A Ayres, A. Spec, L. Blair, Anita Afghanzada, Natalie Schodl, Lana Wahid, John J. Engemann, Gloria Pinero, Beth McLendon-Arvik, Lynn Whitt, Jenny Shroba, Elizabeth L Salsgiver, Candace Alleyne, Anna Gwak, Nicholas Pickell, Jack Spagnoletti, Samson Goh, K. Robb, Michael Cenname, Catherine Small, M. Plate, R. Burgos, Brenna Lindsey, Fischer Herald, Stephanie L. Echeverria, Dorendra Lewis, Mahesh Patel, C. Bengtson, A. Schmid, Kimberly Lovell, C. Lovelett, D. Soule, Daniel Jaremczuk, Jennie Flanagan, Cameron K. Murray, Kylie Sands, Kyle Flint, Sara Mohaddes, Caryn Harrington, Kylie Broughal, David Sogoian, Karen Cox, H. Javeri, Philip O. Ponce, D. O. Dixon, Jason E. Bowling, J. Patterson, B. S. Taylor, Ruth C. Serrano, Kaylin Sallee, Robin E Tragus, G. Catano, Irma Scholler, R. Barajas, Armando Garcia, Bridgette Soileau, P. Heard, Manuel Camilo Endo Carvajal, Rukevwe Ehwarieme, Divya Chandramohan, A. Cabo, Abdelhameed Nawwar, C. Quill, Nayeem Choudhury, Ashley Arrington, Isaiah Holyfield, Abby Smith, Glenda F. Brown, Kyle Varner, Joni Baxter, Tracy Roundy, M. Co, Mireya Wessolossky, Juan Perez-Velazquez, Jennifer Holter-Chakrabarty, Brittany Karfonta, Juvaria Anjum, Jai Marathe, Myriam Castagne, D. Mompoint, Ryan Schroeder, Mallika Rao, John N. Nguyen, J. Plewa, Sue Donlinger, Mary Breslin, S. Dodson, Mitch Jenkins, John C. Williamson, E. Middleton, M. Tavadze, Romai Sebhatu, Jessica Pierobon, N. Miller, John Lee, Pratik Doshi, A. Dentino, Jessica G Martin, Erik Hinojosa, Pablo Torres, R. Sánchez, Gladys Murga, Silvana de la Gala, Jhon Chaiña, J. Ramos, Jenny Malca, Kathia Castillo, Johana Calderon Galvez, Maria Lyda Icochea Perez, Claudia Carolina Becerra Nunez, Sandra Betteta Riondato, Sandra Delgado Málaga, Cecilia Barreda Sánchez, Sylvia Sánchez Morales, Myriam Yaringano Palacios, Dora Galarza Cuba, Ivan Hermenegildo, Mayra Falla Benites, Stefania Neyra, J. Hernández, Victoria García, Katherine Palacios, Miluska Matos, Fiorella Zuloeta, Fiorella del Carpio, Gloria Chacaltana, Carmen de la Cruz, Felipe Ceriolli Breda, Mauricio Mello Roux Leite, T. Milbradt, L. Rodeles, N. Benzaquén, Sebastian Pezzini, Lucila Alberdi, P. Serravalle, Giulia Russo, F. Ferini, M. Guala, Alejandro Crespo, Agostina Benitez, Maria Elena Cristaldi, Paula Di Renzo, Corina Gramagalia, Antonela Tessini, Joana Evelin Alonso, Carmen Pic, Georgina Ceraldi, Azucena Mondino, Iliana Higareda Almaraz, Víctor Hugo Madrigal Robles, María Fernanda Rosas Ismerio, Maria Fernanda Rodarte Rodriguez, Norma Esther Olmos Meza, Norma Esther de la Cruz Barba, Ana Maria Alba Ponce, Juan Calderón, Eduardo Borsetta, Noemí Sandoval, Daniela Vazquez, M. Mansilla, M. Molina, Yamila Jara, L. D. de Bona, Maria Eduarda Claus, Arthur Pille, M. Lahitte, Mariángeles Fenés, C. Bianchi, María Emilia Miserere, M. F. Alzogaray, Halbert Christian Sanchez Carrillo, Aldana Mano, Myrna Zuain, J. Toibaro, Valeria Pachioli, Sebastián Chaio, Natalia Malamud, David B. Bharucha, Patrick B. Dorr, J. Sadeh, S. Kelly, M. Stevens, H. Cao, A. DeZure, K. Juneja, Mazin Abdelghany, Theresa Jasion, R. Olson, Mary C. Roebuck, J. Huvane, C. Lindsell, J. Leimberger, E. Yow, Zhen Huang, Hwasoon Kim, Carla Anderson, Carrie Elliott, Merri Swartz, Jyotsna Garg, Neta Nelson, Divya Kalaria, Ketty Philogene, T. Schulz, Averie Kuek, Fatou Bah, Jarrard Mitchell, E. Polo, Michelle Wong, Sharon Baldan, S. Mendez, B. Stevens, M. Toledo, Talita Abba, Emma Herrejon, Cristina Gómez, Georgeta Mardari, Neeraja Putta, Robin Mason, Holli A. Hamilton, Derek Eisnor, A. O'Rourke, Aditi Patel, B. Brody, Anna Chiang, B. Lind, Lilli M. Portilla, Ami D. Gadhia, S. Vepa, Emily Carlson Marti, Bobbi Gardner, J. Rutter, Clare Schmitt, Michael Kurilla   +356 more
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