Results 141 to 150 of about 53,114 (305)

Chironomid‐based summer temperature reconstruction of the Eemian–Weichselian transition at Lichtenberg, northern Germany

open access: yesBoreas, EarlyView.
Understanding the temperature variability of past interglacial cycles is essential to predict future climates. We present a new summer temperature reconstruction, based on the subfossil chironomid record from a small palaeolake adjacent to the Middle Palaeolithic site of Lichtenberg, northern Germany. The record spans from the Saalian late glacial over
Sonja Rigterink   +10 more
wiley   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz   +8 more
wiley   +1 more source

Homo luzonensis and the role of homoplasy in the morphology of hominin insular species

open access: yesCladistics, EarlyView.
Abstract Homo luzonensis lived during the upper Pleistocene in the northern Philippines, east of the Wallace line. The few specimens attributed to this species show a mosaic of plesiomorphies for the genus Homo and apomorphies found in upper Pleistocene Homo species.
Pierre Gousset   +4 more
wiley   +1 more source

Occupational Contact Urticaria, Protein Contact Dermatitis and Concomitant Airway Diseases in the Finnish Register of Occupational Diseases in 2005–2020: Main Causes and Occupations at Risk

open access: yesContact Dermatitis, EarlyView.
This Finnish registry study shows that concomitant occupational asthma and rhinitis are common in patients with occupational contact urticaria or protein contact dermatitis, often sharing the same exposure. When evaluating occupational immediate allergy, both skin and airway symptoms should be considered.
Ville Ojanen   +4 more
wiley   +1 more source

Public abattoirs [PDF]

open access: yesPublic Health, 1905
openaire   +1 more source

Analysis of socio-economic aspects of local and national organic farming markets; final report for Defra [PDF]

open access: yes
The purpose of this study was to take a fresh look at the nature of organic production, consumption and marketing in England and Wales in order to better assess its current and likely contribution to rural development and its ability to meet consumer ...
Butler, Allan J.   +7 more
core   +1 more source

Dentifrices for preventing erosive tooth wear: An in vitro comparative study

open access: yesEuropean Journal of Oral Sciences, EarlyView.
Abstract Erosive tooth wear is a progressive condition that compromises enamel structure and requires preventive strategies. This in vitro study aimed to compare the protective effects of fluoride‐based dentifrices containing various bioactive agents on sound enamel subjected to simulated erosive–abrasive challenges.
Juliellen Luiz da Cunha   +6 more
wiley   +1 more source

Sustainable control of cyathostomin infections in practice

open access: yesEquine Veterinary Education, EarlyView.
Summary Cyathostomins are the most prevalent helminths in horses and are found in nearly all grazing groups. These parasites have been shown to exhibit widespread anthelmintic resistance and can cause clinical disease, so they are a growing concern.
J. B. Matthews, T. S. Mair
wiley   +1 more source

Local conflict and development projects in Indonesia : part of the problem or part of a solution ? [PDF]

open access: yes
Drawing on an integrated mixed methods research design, the authors explore the dynamics of the development-conflict nexus in rural Indonesia, and the specific role of development projects in shaping the nature, extent, and trajectories of"everyday ...
Barron, Patrick   +2 more
core  

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