Results 111 to 120 of about 507,524 (341)

Multidrug resistance ABC transporters [PDF]

FEBS Letters, 2003
Clinical multidrug resistance is caused by a group of integral membrane proteins that transport hydrophobic drugs and lipids across the cell membrane. One class of these permeases, known as multidrug resistance ATP binding cassette (ABC) transporters, translocate these molecules by coupling drug/lipid efflux with energy derived from the hydrolysis of ...
openaire   +2 more sources

Low‐Dimensional MOF Nanoarchitectonics: Progress in MOF‐2D Material Hybrid Architectures for Energy Conversion and Storage

Advanced Materials, EarlyView.
This review highlights the integration of metal‐organic frameworks (MOFs) and two‐dimensional (2D) materials through dimensional interface engineering. By addressing intrinsic limitations like poor conductivity and agglomeration, these hybrid architectures optimize interfacial charge and mass transport.
Prashant Dubey, Norman C.‐R. Chen, Xiangyang Liu, Yongqi Yin, Keisuke Shirasaki, Kevin C.‐W. Wu, Yingji Zhao, Yusuke Yamauchi   +7 more
wiley   +1 more source

A defective ABC transporter of the MRP family, responsible for the bean lpa1 mutation, affects the regulation of the phytic acid pathway, reduces seed myo-inositol and alters ABA sensitivity [PDF]

, 2011
We previously identified the lpa1 (low phytic acid) 280-10 line that carries a mutation conferring a 90% reduction in phytic acid (InsP6) content. In contrast to other lpa mutants, lpa1(280-10) does not display negative pleiotropic effects.
Bollini, Roberto, Brearley, Charles A., Campion, Bruno, Cassani, Elena, Doria, Enrico, Forti, Luca, Nielsen, Erik, Panzeri, Dario, Pilu, Roberto, Sparvoli, Francesca, Tagliabue, Giovanni   +10 more
core   +1 more source

Droplet Electricity Generators With Maximized Energy Collection Zone Enabled by Aloe‐Inspired Midrib and Cuticle

Advanced Materials, EarlyView.
An Aloe‐pinspired droplet electricity generator (A‐DEG) overcomes the limited energy collection zone of conventional DEGs by guiding impact droplets through a channeling midrib and artificial cuticle. The channeling midrib induces uni‐directional droplet spreading, while the artificial cuticle on the midrib further reinforces this behavior through its ...
Gibeom Lee, Eunbyeol Kim, Kyongtae Choi, Minjun Song, Sunmin Jang, Dongwhi Choi, Donghyun Seo, Min‐Gyu Lee, Younghoon Lee   +8 more
wiley   +1 more source

ABC transporters: bacterial exporters

Microbiological Reviews, 1993
The ABC transporters (also called traffic ATPases) make up a large superfamily of proteins which share a common function and a common ATP-binding domain. ABC transporters are classified into three major groups: bacterial importers (the periplasmic permeases), eukaryotic transporters, and bacterial exporters.
M J, Fath, R, Kolter
openaire   +2 more sources

Diversity of ABC transporter genes across the plant kingdom and their potential utility in biotechnology

BMC Biotechnology, 2016
BackgroundThe ATP-binding cassette (ABC) transporter gene superfamily is ubiquitous among extant organisms and prominently represented in plants. ABC transporters act to transport compounds across cellular membranes and are involved in a diverse range of
Thomas Lane, C. Rempe, Jack Davitt, M. Staton, Yanhui Peng, D. Soltis, D. Soltis, M. Melkonian, M. Deyholos, Jim Leebens-Mack, Mark W. Chase, Mark W. Chase, Carl J. Rothfels, D. Stevenson, S. Graham, Jun Yu, Tao Liu, J. Pires, P. Edger, Yong Zhang, Yinlong Xie, Yinlong Xie, Ying Zhu, E. Carpenter, G. Wong, C. Stewart   +25 more
semanticscholar   +1 more source

Phase Diagrams Enable Solid‐State Battery Design

Advanced Materials Interfaces, EarlyView.
Batteries are non‐equilibrium devices with inherent thermodynamic driving forces to react at interfaces, regardless of kinetics or operating conditions. Chemical potential mismatches across interfaces are dissipated via interfacial reactions. In this work, it is illustrated how phase diagrams and chemical potential maps predict degradation pathways but
Nathaniel L. Skeele, Matthias T. Agne
wiley   +1 more source

A Network of SLC and ABC Transporter and DME Genes Involved in Remote Sensing and Signaling in the Gut-Liver-Kidney Axis. [PDF]

, 2019
Genes central to drug absorption, distribution, metabolism and elimination (ADME) also regulate numerous endogenous molecules. The Remote Sensing and Signaling Hypothesis argues that an ADME gene-centered network-including SLC and ABC "drug" transporters,
Bush, Kevin T, Nigam, Sanjay K, Rosenthal, Sara Brin   +2 more
core   +1 more source

Relocation of active site carboxylates in major facilitator superfamily multidrug transporter LmrP reveals plasticity in proton interactions [PDF]

, 2016
The expression of polyspecific membrane transporters is one important mechanism by which cells can obtain resistance to structurally different antibiotics and cytotoxic agents.

core   +2 more sources

ABC transporter research: going strong 40 years on

Biochemical Society Transactions, 2015
In most organisms, ABC transporters constitute one of the largest families of membrane proteins. In humans, their functions are diverse and underpin numerous key physiological processes, as well as being causative factors in a number of clinically ...
F. Theodoulou, I. Kerr
semanticscholar   +1 more source