Glycosomal ABC transporter 3 (GAT3) deletion enhances the oxidative stress responses and reduces the infectivity of Trypanosoma cruzi. [PDF]
Lima DA +8 more
europepmc +1 more source
Cigarette Smoke Exposure Attenuates T2R‐Mediated Apoptosis in Head and Neck Squamous Cell Carcinoma
ABSTRACT Background Tobacco use is associated with worse outcomes in head and neck squamous cell carcinoma (HNSCC). Bitter taste receptor (T2R) activation induces apoptosis via calcium‐dependent signaling, and higher T2R expression correlates with increased survival in HNSCC.
Kyle Polen +10 more
wiley +1 more source
Two stages of substrate discrimination dictate selectivity in the Escherichia coli MetNI-Q ABC transporter system. [PDF]
Yang JG +4 more
europepmc +1 more source
Genome-Wide Identification, Function, and Expression Analysis of the ABC Transporter Gene Family in Forest Musk Deer (<i>Moschus berezovskii</i>) Under Musk Secretion Stage. [PDF]
Ren YY +8 more
europepmc +1 more source
Combining clinical data with serum proteomics and metabolomics, the HGB–CAPZB–acetic acid model was developed as a potential diagnostic index to distinguish the active and stable stages of Helicobacter pylori‐infected chronic gastritis, and the related mechanism was explored through multi‐omics.
Tiantong Jiang +7 more
wiley +1 more source
Structure of a dimeric full-length ABC transporter. [PDF]
Bickers SC +3 more
europepmc +1 more source
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi +18 more
wiley +1 more source
Integrated pan-cancer analysis revealed therapeutic targets in the ABC transporter protein family. [PDF]
Masood MBE +6 more
europepmc +1 more source
A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione +2 more
wiley +1 more source
Conformational equilibrium of an ABC transporter analyzed by luminescence resonance energy transfer. [PDF]
Zoghbi ME +2 more
europepmc +1 more source

