Results 121 to 130 of about 6,676 (188)

Multidrug resistance-associated protein 4 is a bile transporter of Clonorchis sinensis simulated by in silico docking

Parasites & Vectors, 2017
Background Multidrug resistance-associated protein 4 (MRP4) is a member of the C subfamily of the ABC family of ATP-binding cassette (ABC) transporters. MRP4 regulates ATP-dependent efflux of various organic anionic substrates and bile acids out of cells.
Fuhong Dai, Won Gi Yoo, Ji-Yun Lee, Yanyan Lu, Jhang Ho Pak, Woon-Mok Sohn, Sung-Jong Hong   +6 more
doaj   +1 more source

Effects of the Protein Kinase Inhibitor PKC412 on Gene Expression and Link to Physiological Effects in Zebrafish Danio rerio Eleuthero-Embryos [PDF]

, 2017
To identify molecular effects of the antineoplastic agent protein kinase C inhibitor 412 (PKC412) (midostaurin), we applied gene expression profiling in zebrafish using whole-genome microarrays.
Affolter, Markus, Fent, Karl, Hoeger, Birgit, Küry, Michael, Lenard, Anna, Oggier, Daniela M.   +5 more
core  

Multidrug Resistance Protein 4 (ABCC4)-mediated ATP Hydrolysis [PDF]

Journal of Biological Chemistry, 2004
Zuben E. Sauna, Krishnamachary Nandigama, Suresh V. Ambudkar   +2 more
openaire   +1 more source

Comparing ATPase activity of ATP-binding cassette subfamily C member 4, lamprey CFTR, and human CFTR using an antimony-phosphomolybdate assay

Frontiers in Pharmacology
Introduction: ATP-binding cassette (ABC) transporters use the hydrolysis of ATP to power the active transport of molecules, but paradoxically the cystic fibrosis transmembrane regulator (CFTR, ABCC7) forms an ion channel.
Guiying Cui, Kerry M. Strickland, Analia J. Vazquez Cegla, Nael A. McCarty   +3 more
doaj   +1 more source

Role of MRP4 (ABCC4) in Platelet Adenine Nucleotide-Storage [PDF]

The American Journal of Pathology, 2010
Gabriele Jedlitschky, Marco Cattaneo, Lena E. Lubenow, Dieter Rosskopf, Anna Lecchi, Andrea Artoni, Giovanna Motta, Juliane Nießen, Heyo K. Kroemer, Andreas Greinacher   +9 more
openaire   +1 more source

Identification of associated single nucleotide polymorphism markers for early prediction of pyometra in companion dogs

Journal of Animal Reproduction and Biotechnology
Background: Pyometra, involves pus accumulation that can lead to death if detected late, making early diagnosis and management crucial, and it is more common in older dogs.
Seo Young Bae, Gwang Hyeon Lee, Hong Sik Kong   +2 more
doaj   +1 more source

Changes in the Expression of miR-381 and miR-495 Are Inversely Associated with the Expression of the MDR1 Gene and Development of Multi-Drug Resistance

, 2015
Multidrug resistance (MDR) frequently develops in cancer patients exposed to chemotherapeutic agents and is usually brought about by over-expression of P-glycoprotein (P-gp) which acts as a drug efflux pump to reduce the intracellular concentration of ...
Fan, Jun Y., Gong, Guangming, Hu, Yiqiao, Li, Zhen, Mao, Zhiyong, Ohms, Stephen J, Shannon, M. Frances, Wang, Qiao, Xu, Yan   +8 more
core   +1 more source

ABCC4 Gene [PDF]

, 2020
openaire   +1 more source

ABCC4 wt Allele [PDF]

, 2020
openaire   +1 more source

E-cigarette aerosols induce unfolded protein response in normal human oral keratinocytes. [PDF]

, 2019
Objective: Since the introduction in 2004, global usage of e-cigarettes (ECs) has risen exponentially. However, the risks of ECs on oral health are uncertain.
Chen, Wei, Cui, Li, Elzakra, Naseim, Hu, Shen, Ji, Eoon Hye, Lee, Eon S, Messadi, Diana, Sun, Bingbing, Xia, Tian, Zhu, Yifang   +9 more
core