Results 141 to 150 of about 3,675 (154)
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ABCC4 Decreases docetaxel and not cabazitaxel efficacy in prostate cancer cells in vitro.
Anticancer research, 2013This study aimed to investigate cabazitaxel efficacy in a model for docetaxel-resistant prostate cancer cells and to evaluate the involvement of ATP-cassette binding protein 4 (ABCC4) with regard to multidrug resistance.Docetaxel and cabazitaxel sensitivity was measured in PC3 and R3327-MATLyLu (MLL) cell lines, using the sulforhodamine B (SRB) assay ...
Oprea-Lager D.E. +5 more
openaire +3 more sources
ABCC4 suppresses glioblastoma progression and recurrence by restraining cGMP-PKG signalling
British Journal of CancerCyclic nucleotides are critical mediators of cellular signalling in glioblastoma. However, the clinical relevance and mechanisms of regulating cyclic nucleotides in glioblastoma progression and recurrence have yet to be thoroughly explored.In silico, mRNA, and protein level analyses identified the primary regulator of cyclic nucleotides in recurrent ...
Jung-Ying Chiang +9 more
openaire +2 more sources
Dual-Targeting of miR-124-3p and ABCC4 Promotes Sensitivity to Adriamycin in Breast Cancer Cells
Genetic Testing and Molecular Biomarkers, 2019Xinguang Qiu, Mengquan Li
exaly
Molecular model of the outward facing state of the human multidrug resistance protein 4 (MRP4/ABCC4)
Bioorganic and Medicinal Chemistry Letters, 2008Aina Westrheim Ravna
exaly