Results 141 to 145 of about 3,461 (145)
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ABCC4 suppresses glioblastoma progression and recurrence by restraining cGMP-PKG signalling

British Journal of Cancer
Cyclic nucleotides are critical mediators of cellular signalling in glioblastoma. However, the clinical relevance and mechanisms of regulating cyclic nucleotides in glioblastoma progression and recurrence have yet to be thoroughly explored.In silico, mRNA, and protein level analyses identified the primary regulator of cyclic nucleotides in recurrent ...
Jung-Ying Chiang   +9 more
openaire   +2 more sources

Androgen regulation of multidrug resistance‐associated protein 4 (MRP4/ABCC4) in prostate cancer

The Prostate, 2008
AbstractBACKGROUNDMRP4/ABCC4 is an ATP‐binding cassette transporter expressed in normal prostate. This study aimed to define the pattern of MRP4/ABCC4 expression in normal and malignant prostate tissue and the relationship of MRP4/ABCC4 expression and function in response to androgen signaling.METHODSEighty‐four radical prostatectomy specimens from ...
Ho, L.L.   +9 more
openaire   +3 more sources

ABCC4 Impacts Megakaryopoiesis by Regulating Intracellular cAMP levels

The Journal of Pharmacology and Experimental Therapeutics, 2023
Sabina Ranjit   +7 more
openaire   +1 more source

Protein Kinase A Activation Promotes ABCC4 Protein Network Assembly

The Journal of Pharmacology and Experimental Therapeutics
Sabina Ranjit   +11 more
openaire   +1 more source

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