Results 41 to 50 of about 5,533 (163)

Glycoprotein IIb/IIIa inhibitors for cardiogenic shock complicating acute myocardial infarction: a systematic review, meta-analysis, and meta-regression

Journal of Intensive Care, 2020
Background Cardiogenic shock complicates 5–10% of myocardial infarction (MI) cases. Data about the benefit of glycoprotein IIb/IIIa inhibitors (GPI) in these patients is sparse and conflicting. Methods We performed a systematic review, meta-analysis, and
Carolina Saleiro, Rogério Teixeira, Diana De Campos, João Lopes, Bárbara Oliveiros, Marco Costa, Lino Gonçalves   +6 more
doaj   +1 more source

Small molecule– and peptide–drug conjugates addressing integrins: A story of targeted cancer treatment

Journal of Peptide Science, Volume 30, Issue 7, July 2024.
The development of highly affine, selective peptides and small molecules in recent years has allowed peptide drugs (PDCs) and small molecule–drug conjugates (SMDCs) to increasingly compete with antibody–drug conjugates (ADCs). This review summarises and describes integrin‐addressing PDCs and SMDCs, while highlighting points of great interest.
Jannik Paulus, Norbert Sewald
wiley   +1 more source

Eptifibatide-induced acute profound thrombocytopenia in a patient with left main artery plaque rupture complicated by cardiogenic shock and gastrointestinal bleeding

Journal of Clinical and Preventive Cardiology, 2021
Eptifibatide inhibits platelet aggregation by reversibly binding to the platelet receptor glycoprotein (GP) IIb/IIIa of human platelets, thus preventing the binding of fibrinogen and adhesion proteins such as fibronectin, vitronectin, and von Willebrand ...
Savvy Nandal, William Van Gaal, Francis A Ponnuthurai   +2 more
doaj   +1 more source

Biosensing materials for monoclonal antibody detection: An overview

Responsive Materials, Volume 2, Issue 2, May 2024.
This article provides an overview of the recent advances and functional applications of biosensing materials for monoclonal antibody (mAb) detection. In the review, we present the approaches by which mAb receptors are combined with materials to construct responsive analytical platforms, enabling real‐time monitoring and diagnosis.
Yuxin Zhang, Fang Fan, Yifeng Chai, Xiaofei Chen   +3 more
wiley   +1 more source

Stent thrombosis with an aneurysm 7 years after a drug eluting stent implantation

Indian Heart Journal, 2014
We report a case of very late stent thrombosis 7 years post sirolimus eluting stent implantation presenting as ST elevation MI while on dual antiplatelet therapy. Angiography revealed an aneurysm at the proximal end of the stent.
Pritam Patil, Arvind Sethi, Upendra Kaul
doaj   +1 more source

Perioperative complications of arteriovenous tirofiban administration versus oral dual antiplatelet therapy for stent‐assisted embolization treated aneurysmal subarachnoid hemorrhage: A retrospective, controlled cohort analysis

Brain and Behavior, Volume 14, Issue 2, February 2024.
Abstract Background Major perioperative complications of stent‐assisted embolization treated for aneurysmal subarachnoid hemorrhage patients include the formation of thromboembolic events (TEs) and hemorrhagic events (HEs), for which antiplatelet protocols play a key role.
Kaishan Wang, Yujie Chen, Yao Xu, Chen Yang, Zhaopan Lai, Binbin Tan, Gang Zhu, Hongping Miao   +7 more
wiley   +1 more source

Antiplatelet and Antithrombotic Activities of Lespedeza cuneata via Pharmacological Inhibition of Integrin αIIbβ3, MAPK, and PI3K/AKT Pathways and FeCl3‐Induced Murine Thrombosis

Evidence-Based Complementary and Alternative Medicine, Volume 2024, Issue 1, 2024.
Cardiovascular diseases (CVDs) have been the major cause of mortality all around the globe. Lespedeza cuneata abbreviated as L. cuneata with the authority name of Dumont de Courset (G. Don) is a perennial flowering plant commonly grown in Asian countries such as Korea, Japan, China, and Taiwan. We aimed to investigate the L.
Abdul Wahab Akram, Evelyn Saba, Man Hee Rhee, Sultan Zahiruddin   +3 more
wiley   +1 more source

Antiphospholipid syndrome and acute myocardial infarction: Treatment with thrombectomy and abciximab

Revista Portuguesa de Cardiologia, 2014
Antiphospholipid syndrome (APS) is an autoimmune coagulation disorder that manifests clinically as venous and arterial thrombosis, and may affect any tissue or organ. Coronary artery involvement, however, is very rare.
Vicens Martí, Filipe Seixo, Miguel Santaló, Antonio Serra   +3 more
doaj  

Early and long-term outcome of elective stenting of the infarct-related artery in patients with viability in the infarct-area: Rationale and design of the Viability-guided Angioplasty after acute Myocardial Infarction-trial (The VIAMI-trial)

Current Controlled Trials in Cardiovascular Medicine, 2004
Background Although percutaneous coronary intervention (PCI) is becoming the standard therapy in ST-segment elevation myocardial infarction (STEMI), to date most patients, even in developed countries, are reperfused with intravenous thrombolysis or do ...
Visser Cees A, Bronzwaer Jean GF, Kamp Otto, Veen Gerrit, van Loon Ramon B, Visser Frans C   +5 more
doaj   +1 more source

Comparison between Intracoronary Abciximab and Intravenous Eptifibatide Administration during Primary Percutaneous Coronary Intervention of Acute ST-Segment Elevation Myocardial Infarction

Journal of Tehran University Heart Center, 2015
Background: Administration of glycoprotein IIb/IIIa inhibitors is an effective adjunctive treatment strategy during primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI).
MohammadHasan Namazi, Morteza Safi, Hosein Vakili, Habibollah Saadat, Esfandiar Karimi, Ramin Khameneh-Bagheri   +5 more
doaj