Results 41 to 50 of about 591,055 (229)

Role of aortic calcification, stiffness and wave reflections in cardiovascular risk in dialysis patients: Baseline data from the CORD study

Artery Research, 2010
Background: Accurate cardiovascular risk estimation in dialysis patients remains challenging because different pathogenetic mechanisms act simultaneously in this heterogeneous population.
Francis Verbeke, Raymond Vanholder, Pieter L. Rensma, Björn Wikström, Per Bruno Jensen, Jean-Marie Krzesinski, Merete Rasmussen, Wim Van Biesen, Eero Honkanen,   +9 more
doaj   +1 more source

Abdominal aortic calcification in dialysis patients: results of the CORD study [PDF]

Nephrology Dialysis Transplantation, 2008
Patients with chronic kidney disease stage 5 have a high prevalence of vascular calcification, but the specific anatomical distribution and severity of abdominal aortic calcification (AAC), in contrast to coronary calcification, is less well documented. AAC may be recorded using plain radiographs.
Honkanen, Eero, Kauppila, Leena, Wikström, Björn, Rensma, Pieter L, Krzesinski, Jean-Marie, Aasarod, Knut, Verbeke, Francis, Jensen, Per Bruno, Mattelaer, Pierre, Volck, Birgitte, study group], [CORD, Christensen [CORD study group], Jeppe Hagstrup, Jensen [CORD study group], Jens Dam   +12 more
openaire   +4 more sources

Data supporting the effects of xanthine derivative KMUP-3 on vascular smooth muscle cell calcification and abdominal aortic aneurysm in mice

Data in Brief, 2020
No pharmacotherapy in the clinical setting has been available to alter the natural history of abdominal aortic aneurysm (AAA). Targeting vascular smooth muscle cell (VSMC) dysfunction during the pathogenesis of AAA, including phenotypic switch and ...
Chao-Han Lai, Ching-Wen Chang, Fang-Tzu Lee, Cheng-Hsiang Kuo, Jong-Hau Hsu, Chung-Pin Liu, Hua-Lin Wu, Jwu-Lai Yeh   +7 more
doaj   +1 more source

Association of monocyte and lymphocyte ratio with risk of abdominal aortic calcification. [PDF]

PLoS One
Objectives The aim of the study was to evaluate the relationship between monocyte and lymphocyte ratio (MLR) with severe AAC. Methods This cross-sectional study enrolled 3041 patients with AAC from the National Health and Nutrition Examination Survey 2013–2014.
Yan W, Hu T.
europepmc   +4 more sources

Visceral and Ectopic Abdominal Fat Effect on the Calcification of the Abdominal Aorta and Its Branches—An MSCT Study

Life, 2023
Visceral and ectopic fat accumulation might have an impact on the atherosclerotic calcification of abdominal arteries. The pattern of calcification of the abdominal aorta and its branches is not fully investigated.
Ivan Ordulj, Frano Šarić, Mirko Tandara, Kristian Jerković, Sanja Lovrić Kojundžić, Maja Marinović Guić, Miodrag Beneš, Danijela Budimir Mršić   +7 more
doaj   +1 more source

Abdominal Aortic Calcifications in Patients with Chronic Kidney Disease: A Single Center Study in Lahore, Pakistan

Life and Science
Objective: To determine the prevalence of abdominal aortic calcification in patients diagnosed with chronic kidney disease stage III to V. Study Design: Cross-sectional study.
Mubashir Dilawar, Omer Sabir, Muhammad Bilal Basit, Adnan Hussain Shahid, Andleeb Kanwal, Syed Ahtesham Ali Shah   +5 more
doaj   +1 more source

Procyanidin B2 Reduces Vascular Calcification through Inactivation of ERK1/2-RUNX2 Pathway

Antioxidants, 2021
Vascular calcification is strongly associated with atherosclerotic plaque burden and plaque instability. The activation of extracellular signal-regulated kinase 1/2 (ERK1/2) increases runt related transcription factor 2 (RUNX2) expression to promote ...
Yingquan Liang, Guilan Chen, Feng Zhang, Xiaoxiao Yang, Yuanli Chen, Yajun Duan, Maoyun Yu, Shuang Zhang, Jihong Han   +8 more
doaj   +1 more source

Risk stratification by pre-operative cardiopulmonary exercise testing improves outcomes following elective abdominal aortic aneurysm surgery : a cohort study [PDF]

, 2013
Background: In 2009, the NHS evidence adoption center and National Institute for Health and Care Excellence (NICE) published a review of the use of endovascular aneurysm repair (EVAR) of abdominal aortic aneurysms (AAAs).
Imray, C. (Chris), Saedon, Mahmud H., Hill, Christopher E., Higman, Daniel, Yow, Heng, Asif Mahmood, Daniel Higman, Watson, Duncan, Dr., Heng Yow, Joanna Shakespeare, Christopher HE Imray, Colette Marshall, Stephen J Goodyear, Shakespeare, Joanna, Goodyear, Stephen J., Mahmood, Asif, Mahmud Saedon, Duncan Watson, Marshall, Colette, Dr., Christopher E Hill   +19 more
core   +1 more source

A Radiographic Study on the Associations of Age and Prevalence of Vertebral Fractures with Abdominal Aortic Calcification in Japanese Postmenopausal Women and Men

Journal of Osteoporosis, 2010
The purpose of the present study was to determine the associations of age and history of non- and low-traumatic fractures with the severity of abdominal aortic calcification in Japanese postmenopausal women and men. Four hundred and one Japanese persons (
Jun Iwamoto, Hideo Matsumoto, Tsuyoshi Takeda, Yoshihiro Sato, Mitsuyoshi Uzawa   +4 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source