Results 51 to 60 of about 149,144 (263)

Abdominal injury at Mbarara Regional Referral Hospital, Uganda [PDF]

, 2016
Background: Trauma poses a major public health challenge in Africa. This study was aimed at determining the prevalence, patterns and predisposing factors of abdominal injury in Mbarara Regional Referral Hospital (MRRH).Methods: A standard questionnaire ...
Bajunirwe, F, Kitya, D, Kyamanywa, P, Ruhinda, G   +3 more
core   +2 more sources

Label‐Free Dual‐Modal Photoacoustic/Ultrasound Localization Imaging for Studying Acute Kidney Injury

Advanced Science, EarlyView.
This work develops a 3D label‐free photoacoustic/super‐resolution ultrasound imaging system as a comprehensive non‐invasive tool for acute kidney injury (AKI) study. This technique visualizes the intricate structure of renal microvessels and provides critical physiological insights, including renal hemodynamics and oxygenation.
Shensheng Zhao, Xingxing Zhang, Keith Bailey, Sathvik Pai, Yang Zhao, Yun‐Sheng Chen   +5 more
wiley   +1 more source

Trauma ICU Prevalence Project: the diversity of surgical critical care. [PDF]

, 2019
Background:Surgical critical care is crucial to the care of trauma and surgical patients. This study was designed to provide a contemporary assessment of patient types, injuries, and conditions in intensive care units (ICU) caring for trauma patients ...
, Abid Khan, Adrian A Maung, Amy Stewart, Andre Campbell, Anna Newcomb, Anne Stey, Areg Grigorian, Ashley Keiler-Green, Byron C Drumheller, Casey Hill, Chang Liu, Charles Hu, Chris Culpepper, Christopher P Michetti, Claire Pederson, Clay Cothren Burlew, Dana Ferrari-Light, Daniel C Cullinane, David H Livingston, David J Dries, Dennis Kim, Elisa Moskowitz, Elizabeth D Dauer, Elizabeth Ramey, Eric M Campion, Erik J Teicher, Erin Howell, Evan Elizabeth Rainey, Fady S Nasrallah, Forrest O (Dell) Moore, Graal Diaz, Grace Chang, Grant V Bochicchio, Henrik Berdel, Janika L San Roman, Jason L Sperry, Jason Radowsky, Javier Romero, Jay J Doucet, Jeanette Podbielski, Jeffry Nahmias, Jennifer Mull, Jessica H Ballou, Jessica Huang, Jonathan P Meizoso, Joseph Farhat, Joseph V Sakran, Karen Brasel, Karen J Brasel, Karen Lewandowski, Katherine Corey, Katherine Kelley, Kathryn B Schaffer, Kaushik Mukherjee, Kevin H Martin, Krista Kaups, Len Weireter, Lillian Kao, Lily Tung, Linda Ann Dultz, Lisa M Kodadek, Liz G Penaloza, Manuel Lorenzo, Marie Crandall, Mary-Margaret Brandt, Matthew M Carrick, Meenakshi Rani, Michael Coomaraswamy, Michael Foreman, Michaela A West, Milos Buhavac, Nicole Goulet, Niels D Martin, Paige Farley, Patrick L Bosarge, Philip A Efron, Rachel C Dirks, Rachel L Sensenig, Ram Nirula, Reanna Adams, Rohit K Rasane, Ruth Davis, Samir M Fakhry, Sonlee D West, Tanya L Zakrison, Tatiana C P Cardenas, Thomas Schroeppel, Todd W Costantini, Vaidehi Agrawal, Vincent P Anto, Wendy L Wahl   +91 more
core   +1 more source

Neuronal C/EBPβ Shortens the Lifespan via Inactivating NAMPT

Advanced Science, EarlyView.
Schematic diagram illustrating the mechanism of shortened lifespan in Thy 1‐C/EBPβ transgenic mice and intervention strategies. Briefly, C/EBPβ/AEP escalation in the aging brain triggers NAMPT fragmentation and NAD+ depletion. Knockout of AEP from Thy 1‐C/EBPβ Tg/Tg mice ameliorates cognitive impairments and elongates the lifespan.
Bowei Li, Zhongyun Xie, Mengmeng Wang, Shuke Nie, Zhengjiang Qian, Xin Meng, Xia Liu, Seong Su Kang, Keqiang Ye   +8 more
wiley   +1 more source

Blunt abdominal trauma: the experience in rural India and review of literature [PDF]

, 2019
Background: Blunt Abdominal trauma is one of the most common injuries caused due to road traffic accidents. The rapid increase in number of motor vehicles and its aftermath has caused rapid increase in number of victims due to blunt abdominal trauma.
Ahmed, Mohd Hamid Shafique, Bankar, Sanket, Dalavi, Santosh B., Gurav, Prakash D., Parmar, Ritesh, Tamgadge, Lalit Vishwanath   +5 more
core   +2 more sources

MMP9High Neutrophils are Critical Mediators of Neutrophil Extracellular Traps Formation and Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
During a heart attack, neutrophils rapidly activate and differentiate into a specific subset characterized by high levels of MMP9, a tissue‐damaging enzyme, via the SPI1/CST7 pathway. These neutrophils form harmful net‐like structures (Neutrophil extracellular traps, NETs) that exacerbate heart injury.
Shiyu Hu, Feng Zhang, Jingpu Wang, Jian Zhang, Chenguang Li, Yang Lyu, Yiwen Wang, Rong Huang, Yang Gao, Hongbo Yang, Juying Qian, Wenwen Tang, Jiatian Cao, Junbo Ge   +13 more
wiley   +1 more source

Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects

Advanced Science, EarlyView.
Diallyl trisulfides (DATs) selectively induce cuproptosis in hepatic stellate cells (HSCs) by targeting Ras‐related protein Rab‐18 (RAB18) and regulating lipophagy. DATs promote RAB18 phase separation, enhance mitochondrial‐associated membrane structures (MAMs) formation, and increase succinylation of dihydrolipoamide dehydrogenase (DLD) at K320.
Haoyuan Tian, Shujiang Sun, Xinran Qiu, Junrui Wang, Yuanyuan Gao, Jianmei Chen, Xiang Han, Zhengyang Bao, Xiaohan Guo, Yuqi Sun, Yuxin Lin, Mengru Hu, Feng Zhang, Zili Zhang, Feixia Wang, Shizhong Zheng, Jiangjuan Shao   +16 more
wiley   +1 more source

Penetrating Abdominal Injury by a Large Stone [PDF]

, 2012
Penetrating trauma can be commonly caused by sharp objects. We report a case of penetrating injury of abdomen caused by a fairly large sized stone which is used for sharpening the objects or weapons.
Baitha, K, Kamble, AT, Kaple, MN, Mahakalkar, CC   +3 more
core  

Abdominal functional electrical stimulation to assist ventilator weaning in acute tetraplegia: a cohort study [PDF]

, 2015
Background Severe impairment of the major respiratory muscles resulting from tetraplegia reduces respiratory function, causing many people with tetraplegia to require mechanical ventilation during the acute stage of injury.
Allan, David B., Berry, Helen R., Gollee, Henrik, McCaughey, Euan J., McLean, Alan N.   +4 more
core   +3 more sources

Targeting PTBP3‐Mediated Alternative Splicing of COX11 Induces Cuproptosis for Inhibiting Gastric Cancer Peritoneal Metastasis

Advanced Science, EarlyView.
The splicing factor PTBP3 promotes COX11 exon skipping, allowing gastric cancer organoids to evade cuproptosis. Antisense oligonucleotide drugs targeting PTBP3‐mediated COX11 alternative splicing, in combination with copper ionophores, promote cuproptosis in organoids, thereby providing a therapeutic approach for gastric cancer peritoneal metastasis ...
Yajing Zhou, Chao Dong, Xiaochun Shen, Pengbo Wang, Tao Chen, Weikang Li, Xiaotong Sun, Peiyuan Li, Chengxiang Xu, Kaipeng Duan, Dongbao Li, Jin Zhou   +11 more
wiley   +1 more source