Single‐cell spatial transcriptomics reveals potential molecular mechanisms of Abelmoschus manihot (L.) medic in treating diabetic kidney disease [PDF]
iMetaA clinical study reported that Abelmoschus manihot (L.) Medic (A. manihot), in the form of Huangkui capsule (HKC), combined with irbesartan (IRB) is an effective therapy for patients with diabetic kidney disease (DKD). The bioactive components of HKC are total flavones extracted from A. manihot (TFA).
Chenhua Wu +7 more
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Uji Aktivitas Antikolesterol Ekstrak Etanol Daun Gedi (Abelmoschus Manihot L. Medik) Secara In Vitro
Window of Health, 2020 Perubahan gaya hidup antara lain pola makan menyebabkan pola makan tradisional bergeser ke pola makan barat seperti fast food yang banyak mengandung kalori, lemak dan kolesterol.
Andi Nurjayanti Ilyas +2 more
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Extraction of Flavonoids from the Flowers of Abelmoschus manihot (L.) Medic by Modified Supercritical CO2 Extraction and Determination of Antioxidant and Anti-Adipogenic Activity [PDF]
Molecules, 2016 Abelmoschus manihot (L.) Medic has been used for many years in Chinese traditional medicine. In this study, supercritical CO2 plus a modifier was utilized to extract flavonoids from the flowers of Abelmoschus manihot (L.) Medic.
Jingjing Li, Juan Zhang, Min Wang
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Journal of Hebei University of Science and Technology, 2022 In order to study the biological roles of Abelmoschus manihot (L.) medic polysaccharide (AMP) in vivo and the underlying mechanism,C.elegans was used as a model to analyse the influence of ck(0 mg/mL),low dose group (25 mg/mL),medium dose group (50 mg/mL)
Xingfang DU +3 more
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Research note: Effects of dietary supplementation of Abelmoschus manihot L. flower extract on growth performance, antioxidant capacity, intestinal health, and welfare in broiler chickens [PDF]
Poultry ScienceThe objective of this experiment was to investigate the effects of dietary supplementation of Abelmoschus manihot (AE) L. flower extract on growth performance, antioxidant capacity, intestinal health, and welfare in broiler chickens. A total of 144 one-d-
Gyu Lim Yeom +11 more
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Total flavonoids of Abelmoschus manihot (L.) medic attenuate early renal injury in diabetic kidney disease by modulating the LINC00665/miR-379-5p axis [PDF]
Pharmaceutical BiologyContext: Huangkui capsule (HKC), derived from Abelmoschus manihot (L.) Medic, is clinically utilized for diabetic kidney disease (DKD) treatment. Its primary bioactive components are the total flavonoids of A. manihot (L.) (TFA).
Nan Li +5 more
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Total Extracts of Abelmoschus manihot L. Attenuates Adriamycin-Induced Renal Tubule Injury via Suppression of ROS-ERK1/2-Mediated NLRP3 Inflammasome Activation [PDF]
Frontiers in Pharmacology, 2019 Abelmoschus manihot (L.) Medik. (Malvaceae) is a herb used in traditional Chinese medicine to treat some kidney diseases. To date, the detailed mechanisms by which A. manihot improves some kinds of renal disease are not fully understood.
Wei Li +13 more
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Total extract of Abelmoschus manihot L. alleviates uric acid-induced renal tubular epithelial injury via inhibition of caspase-8/caspase-3/NLRP3/GSDME signaling [PDF]
Frontiers in Pharmacology, 2022 Purpose: The incidence of uric acid (UA)-induced kidney injury is increasing owing to the high incidence of hyperuricemia in recent years. The flower of Abelmoschus manihot (Linneus) Medik is a traditional Chinese medicinal herb widely used in the ...
Zhihui Ding +14 more
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Effects of Abelmoschus manihot (L.) and its combination with irbesartan in the treatment of diabetic nephropathy via the gut–kidney axis [PDF]
Frontiers in PharmacologyBackgroundClinical observations have recently shown that Abelmoschus manihot (L.) in the form of Huangkui capsule (HKC) and in combination with irbesartan (EB) is an effective therapy for diabetic nephropathy (DN) in patients with type 2 diabetes (T2D ...
Hongmei Yu +10 more
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Research note: Effects of dietary Abelmoschus manihot L. flower powder supplementation on growth performance, relative organ weight, and liver status in broiler chickens [PDF]
Poultry ScienceThe objective of this experiment was to assess the impact of dietary Abelmoschus manihot L. flower powder (AMP) supplementation on growth performance, relative organ weight, and liver status in broiler chickens.
Gyu Lim Yeom +8 more
doaj +2 more sources