Results 231 to 240 of about 514,785 (377)

Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2013
K. C. Chan   +17 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Visual Performance Correlation with Corneal Aberrometric Profile and Pupil Size After Implantation of a Trifocal Hydrophobic IOL

open access: yesClinical Ophthalmology
Camille Bosc, Eloïse Le Maléfan, Pauline Boury, Mélanie Bernier, Anne Barrucand Département de Recherche Clinique, Institut Ophtalmologique de l’Ouest (IOO) Jules Verne, Nantes, FranceCorrespondence: Camille Bosc, Département de Recherche Clinique ...
Bosc C   +4 more
doaj  

Identification and classification of chromosomal aberrations in human induced pluripotent stem cells.

open access: yesCell Stem Cell, 2010
Yoav Mayshar   +8 more
semanticscholar   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

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