Results 61 to 70 of about 190,014 (313)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Correction of Eye Wavefront Using Contact Lenses and Their Impact on the Accommodative Response

open access: yesРоссийский офтальмологический журнал, 2018
Eye wavefront aberrations have a strong impact on the formation of an image on the retina and vision quality. A relationship has also been found between the aberrations and accommodation, which plays a significant role in visual performance and ...
E. P. Tarutta   +2 more
doaj   +1 more source

Aberrations of chromosome 8 in myelodysplastic syndromes: Clinical and biological significance [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2006
Introduction: Rearrangements of any single chromosome in human karyotype have been reported in patients with pMDS. Objective: To examine the role of aberrations of chromosome 8 in pathogenesis, clinical presentation and progression of myelodysplastic ...
Marisavljević Dragomir   +3 more
doaj   +1 more source

Exploring the Relationship between Fusion Genes and MicroRNAs in Cancer

open access: yesCells, 2023
Fusion genes are key cancer driver genes that can be used as potential drug targets in precision therapies, and they can also serve as accurate diagnostic and prognostic biomarkers.
Saurav Panicker   +4 more
doaj   +1 more source

Effect of accommodation on peripheral ocular aberrations

open access: yes, 2009
Changes in peripheral aberrations, particularly higher-order aberrations, as a function of accommodation have received little attention. Wavefront aberrations were measured for the right eyes of 9 young adult emmetropes at 38 field positions in the ...
Mathur, Ankit   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Evaluation of corneal topography and higher order aberrations of the fellow eye in unilateral keratoconus

open access: yesJournal of the Egyptian Ophthalmological Society, 2023
Purpose To assess parameters of corneal topography and higher order aberrations (HOAs) data in the apparently normal contralateral eyes of unilateral keratoconus (KC) cases in comparison with normal eyes of healthy individuals. Patients and methods This
Mahmoud Mohamed Attia El Morsy   +4 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Night vision and glare vision thresholds and recovery time in myopic and hyperopic eyes

open access: yesAfrican Vision and Eye Health, 2010
The purpose of this study was to compare night vision and glare vision thresholds and recovery times in myopic and hyperopic eyes. Using a Night Sight Meter, these three parameters were measured in 44 myopic and 44 hyperopic eyes of Black male subjects ...
K. P. Mashige
doaj   +1 more source

Image formation in coronagraphs due to mirror polarization aberrations

open access: yes, 2017
The PSF for astronomical telescopes and instruments depends not only on geometric wavefront aberrations, but also on those polarization aberrations from the polarization properties of reflecting and transmitting surfaces.
Russell A. Chipman, Chipman, Russell A.
core   +1 more source

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