Results 81 to 90 of about 190,014 (313)

Effect of age on components of peripheral ocular aberrations

, 2012
Purpose: \ud To investigate the effect of age on the contributions of the anterior cornea and internal components to ocular aberrations in the peripheral visual field.
Mathur, Ankit, Atchison, David A.
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Peripheral ocular monochromatic aberrations

, 2009
Aberrations affect image quality of the eye away from the line of sight as well as along it. High amounts of lower order aberrations are found in the peripheral visual field and higher order aberrations change away from the centre of the visual field ...
Mathur, Ankit
core  

Contrast sensitivity benefit of adaptive optics correction of ocular aberrations.

, 2011
While correcting the aberrations of the eye produces large increases in retinal image contrast, the corresponding improvement factors in the contrast sensitivity function have been little explored and results are controversial.
S. Marcos, Marcos, Susana, Mathur, A., Mathur, Ankit, Atchison, David A., de Gracia, Pablo, A. Mathur, D. A. Atchison, Gracia, Pablo de, P. de Gracia   +9 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Applying individual rigid scleral contact lenses in visual rehabilitation of patients with an irregular corneal surface. Clinical cases

Российский офтальмологический журнал
Scleral rigid contact lenses efficiently correct the vision of patients with irregular corneas. Purpose. To study the features of contact correction and visual rehabilitation of patients with irregular corneal surface using individual scleral rigid ...
A. V. Ivanova, A. S. Sklyarova, A. T. Khandzhyana, N. V. Khodzhabekyan, I. V. Manukyan   +4 more
doaj   +1 more source

Microfluctuations of Wavefront Aberrations of the Eye

, 2005
The human eye suffers various optical aberrations that degrade the retinal image. These aberrations include defocus and astigmatism, as well as the higher order aberrations that also play an important role in our vision.
Zhu, Mingxia
core