Results 91 to 100 of about 372,775 (305)

Applying individual rigid scleral contact lenses in visual rehabilitation of patients with an irregular corneal surface. Clinical cases

Российский офтальмологический журнал
Scleral rigid contact lenses efficiently correct the vision of patients with irregular corneas. Purpose. To study the features of contact correction and visual rehabilitation of patients with irregular corneal surface using individual scleral rigid ...
A. V. Ivanova, A. S. Sklyarova, A. T. Khandzhyana, N. V. Khodzhabekyan, I. V. Manukyan   +4 more
doaj   +1 more source

Aberration in qualitative multilevel designs

, 2015
Generalized Word Length Pattern (GWLP) is an important and widely-used tool for comparing fractional factorial designs. We consider qualitative factors, and we code their levels using the roots of the unity. We write the GWLP of a fraction ${\mathcal F}$
Chen, Cheng, Fabio Rapallo, Fontana, Fontana, Fontana, Fontana, Fontana, Fontana, Fries, Grömping, Katsaounis, Li, Maria Piera Rogantin, Mukerjee, Pistone, Qin, Qin, Roberto Fontana, Schoen, Suen, Tang, Xu   +22 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Polarization Aberrations [PDF]

The analysis of the polarization characteristics displayed by optical systems can be divided into two categories: geometrical and physical. Geometrical analysis calculates the change in polarization of a wavefront between pupils in an optical instrument.
Chipman, Russell A., Mcguire, James P., Jr.   +1 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Impact of bifocal soft contact lenses and Midrimax on peripheral refraction and eye aberrations in children with myopia

Российский офтальмологический журнал
Purpose of the work: to evaluate the effect of combined use of bifocal soft contact lenses (BSCL) and the combined drug Midrimax (Phenylephrine 5.0%; Tropicamide 0.8%) on peripheral refraction and wavefront aberrations of the eye.
E. P. Tarutta, N. A. Tarasova, S. V. Milash, S. G. Harutunyan, G. A. Markossian   +4 more
doaj   +1 more source

Simultaneous exoplanet detection and instrument aberration retrieval in multispectral coronagraphic imaging

, 2013
High-contrast imaging for the detection and characterization of exoplanets relies on the instrument's capability to block out the light of the host star.
Beuzit, Jean-Luc, Fusco, Thierry, Mouillet, David, Mugnier, Laurent M., Ygouf, Marie   +4 more
core   +3 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source