Results 101 to 110 of about 372,775 (305)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Visual Tasks Dependence of the Neural Compensation for the Keratoconic Eye's Optical Aberrations

Journal of Optometry, 2010
Purpose: To investigate whether “normal” eyes viewing through keratoconic (KC) eye aberrations can achieve a similar visual performance (VP) to that of KC eyes. Method: We measured the high-contrast visual acuity (VA) and the 10, 15 and 20 c/deg contrast
Hélène Rouger, Yohann Benard, Damien Gatinel, Richard Legras   +3 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Evaluation of the Cytogenotoxic Effects of Emulsifiable Concentrate form of Amitraz Pesticide on Allium cepa L

Journal of Applied Sciences and Environmental Management, 2019
The cytogenotoxic effects of emulsifiable concentrate of amitraz pesticides was evaluated using Allium cepa L. test. The root meristems of A. cepa L. were treated with five concentrations (1%, 5%, 10%, 20% and 40%) of the chemical pesticide at 48 h for ...
A.A Adesuyi, K.L Njoku, A.L Ogunyebi, E.O Dada, A.H Adedokun, A.O Jolaoso, M.O Akinola   +6 more
doaj   +1 more source

Annular objective apertures improve resolution of electron microscopes [PDF]

, 1972
Hollow-cone illumination techniques, using an annular objective aperture located behind back focal plane of objective lens, increase image contrast and minimize chromatic ...
Heinemann, K., Poppa, H. R.
core   +1 more source

Aberration considered in relation to the two Star-Streams [PDF]

, 1909
A. S. Eddinǵton
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Lyot-based Low Order Wavefront Sensor: Implementation on the Subaru Coronagraphic Extreme Adaptive Optics System and its Laboratory Performance

, 2014
High throughput, low inner working angle (IWA) phase masks coronagraphs are essential to directly image and characterize (via spectroscopy) earth-like planets.
Baudoz, Pierre, Guyon, Olivier, Jovanovic, Nemanja, Kudo, Tomoyuki, Kuhn, Jonas G, Martinache, Frantz, Serabyn, Eugene, Singh, Garima   +7 more
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Phase Retrieval of One-Dimensional Objects by the Multiple-Plane Gerchberg–Saxton Algorithm Implemented into a Digital Signal Processor

Optics
In the current study, we address the phase retrieval of one-dimensional phase objects from near-field diffraction patterns using the multiple-plane Gerchberg–Saxton algorithm, which is still widely used for phase retrieval.
Varis Karitans, Maris Ozolinsh, Sergejs Fomins   +2 more
doaj   +1 more source