Results 111 to 120 of about 372,775 (305)

Tartrazine induces structural and functional aberrations and genotoxic effects in vivo [PDF]

, 2017
Latifa Khayyat, Amina E. Essawy, Jehan Sorour, Ahmed Soffar   +3 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Computer program for optical systems ray tracing [PDF]

, 1967
Program traces rays of light through optical systems consisting of up to 65 different optical surfaces and computes the aberrations.
Ferguson, T. J., Konn, H.
core   +1 more source

Response to “Severe pernicious anemia with distinct cytogenetic and flow cytometric aberrations mimicking myelodysplastic syndrome” [PDF]

, 2012
Denise A. Wells, Michael R. Loken
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Self-coherent camera as a focal plane wavefront sensor: simulations

, 2009
Direct detection of exoplanets requires high dynamic range imaging. Coronagraphs could be the solution, but their performance in space is limited by wavefront errors (manufacturing errors on optics, temperature variations, etc.), which create quasi ...
Baudoz, Pierre, Galicher, Raphael, Mas, Marion, Rousset, Gerard, Totems, Julien   +4 more
core   +3 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

The Aberrometric Effect of Corneal Plus Power Ring Distribution on Axial Length Growth in Myopic Children Undergoing Orthokeratology Treatment

Children
Background/Objectives: Myopia progression is strongly associated with axial length (AL) elongation, and orthokeratology (Ortho-K) lens design may influence treatment outcomes. This study has the aim to evaluate the impact of lens customization as optical
Ana Maria Espín, Lluisa Quevedo, Jaume Pauné, António Queirós   +3 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Datasets and metadata supporting the published article: Somatic Genetic Aberrations in Benign Breast Disease and the Risk of Subsequent Breast Cancer

, 2020
Zexian Zeng, Andy H. Vo, Xiaoyu Li, Ali Shidfar, Paulette Saldana, Luis Z. Blanco, Xiaoling Xuei, Yuan Luo, Seema A. Khan, Susan E. Clare   +9 more
openalex   +1 more source