Results 111 to 120 of about 190,014 (313)

Anterior corneal, posterior corneal, and lenticular contributions to ocular aberrations

open access: yes, 2016
Purpose: To determine the corneal surfaces and lens contributions to ocular aberrations.\ud \ud Methods: There were 61 healthy participants with ages ranging from 20 to 55 years and refractions –8.25 D to +3.25 D.
Mathur, Ankit   +4 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Off-axis transmission holographic system for recording aquatic particles

open access: yes, 1996
We describe a holographic system for recording particles suspended in water. The hologram plate is located in air, separated from the test tank by an air/glass/water boundary. The holographic emulsion is therefore unaffected by adverse aquatic conditions
Lampitt, RS   +4 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Phase Retrieval of One-Dimensional Objects by the Multiple-Plane Gerchberg–Saxton Algorithm Implemented into a Digital Signal Processor

open access: yesOptics
In the current study, we address the phase retrieval of one-dimensional phase objects from near-field diffraction patterns using the multiple-plane Gerchberg–Saxton algorithm, which is still widely used for phase retrieval.
Varis Karitans   +2 more
doaj   +1 more source

Aberrations of emmetropic subjects at different ages

open access: yes, 2008
We made on-axis aberrations and horizontal peripheral refraction measurements of emmetropic subjects (spherical equivalent −0.88D to +0.75D) aged between 19 and 70 years.
Atchison, David A., Markwell, Emma L.
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Refractive telescope design with digital correction of residual chromatic aberrations

open access: yes, 2019
In general, optical designers employ combinations of multiple lenses with extraordinary dispersion materials to correct chromatic aberrations, which usually leads to considerable volume and weight.
Nie, Yunfeng   +4 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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