Results 121 to 130 of about 190,014 (313)

The Aberrometric Effect of Corneal Plus Power Ring Distribution on Axial Length Growth in Myopic Children Undergoing Orthokeratology Treatment

Children
Background/Objectives: Myopia progression is strongly associated with axial length (AL) elongation, and orthokeratology (Ortho-K) lens design may influence treatment outcomes. This study has the aim to evaluate the impact of lens customization as optical
Ana Maria Espín, Lluisa Quevedo, Jaume Pauné, António Queirós   +3 more
doaj   +1 more source

The Effect of Artificial Tears on Corneal Higher Order Aberrations in Dry Eye Patients

, 2014
Purpose: To assess the effects of artificial tears on corneal higher order aberrations in dry eye patients. Materials and Methods: 30 right eyes of 30 newly diagnosed dry eye patients were evaluated in this prospective study.
Hasan Ali Bayhan, İzzet Can, Seray Aslan Bayhan   +2 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Ocular aberrations of human eyes

, 1991
We have modified an aberroscope technique, developed by\ud Horvland and Howland, to investigate the influence of: 1.\ud Refractive error and 2. Accommodation on ocular aberrations.\ud These authors analysed drawings made by subjects of retinal\ud shadows
Wildsoet, Christine F., Atchison, David A., Collins, Michael J.   +2 more
core  

The role of cardiopulmonary signals in the dynamics of the eye's wavefront aberrations

, 2010
—The role of cardiopulmonary signals in the dynamics\ud of wavefront aberrations in the eye has been examined. Synchronous measurement of the eye’s wavefront aberrations, cardiac function, blood pulse, and respiration signals were taken for a group of ...
Collins, M.J., Iskander, D.R., Muma, M.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Peripheral ocular aberrations in mild and moderate keratoconus

, 2010
Purpose: To investigate the influence of keratoconus on peripheral ocular aberrations.\ud Methods: Aberrations of 7 mild and 5 moderate keratoconics were determined over a 42°horizontal x 32° vertical visual field with a modified COAS-HD aberrometer ...
Andrew H. Tran, Mathur, Ankit, Read, Scott A., McLennan, Roderick, David A. Atchison, Photios P. Tanos, Tran, Andrew, Scott A. Read, Newman, Alexander, Alexander R. Newman, Roderick T. McLennan, Walker, Mitchell, Atchison, David A., Ankit Mathur, Tanos, Photios, Mitchell I. Walker   +15 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Early Clinical and Functional Results of Mixed Astigmatism Correction Depending on the Degree with the High-frequency Excimer Laser Schwind Amaris 1050RS

Oftalʹmologiâ
Purpose. To conduct a prospective comparative study of the early results of mixed astigmatism’s correction by the Femto-LASIK method using the excimer laser Schwind Amaris 1050RS depending on the degree of astigmatism Patients and methods.
O. A. Klokova, R. O. Damashauskas, A. I. Kacharov, A. V. Piskunov, M. S. Geydenrikh, E. I. Diakonova   +5 more
doaj   +1 more source

Ocular aberrations in the peripheral visual field

, 2008
We modified a commercial Hartmann-Shack aberrometer and used it to measure ocular aberrations across the central 42º horizontal x 32º vertical visual fields of five young emmetropic subjects.
Mathur, Ankit, Scott, Dion H., Atchison, David A.   +2 more
core   +1 more source