Results 121 to 130 of about 372,775 (305)

Estimation of ultrasound wave aberration with signals from random scatterers [PDF]

, 2004
Svein‐Erik Måsøy, Bjørn Angelsen, Trond Varslot   +2 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Spherical Aberration Correction Using Refractive-Diffractive Lenses with an Analytic-Numerical Method [PDF]

, 2010
S. Vázquez-Montiel, O. García-Liévanos, J.A. Hernández-Cruz   +2 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Early Clinical and Functional Results of Mixed Astigmatism Correction Depending on the Degree with the High-frequency Excimer Laser Schwind Amaris 1050RS

Oftalʹmologiâ
Purpose. To conduct a prospective comparative study of the early results of mixed astigmatism’s correction by the Femto-LASIK method using the excimer laser Schwind Amaris 1050RS depending on the degree of astigmatism Patients and methods.
O. A. Klokova, R. O. Damashauskas, A. I. Kacharov, A. V. Piskunov, M. S. Geydenrikh, E. I. Diakonova   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Cytogenetic study of the Ukrainian river buffalo (Bubalus bubalis bubalis)

Біологічні студії
Introduction. The article presents the results of the exploration of the karyotype of the Ukrainian population of river buffaloes (Bubalus bubalis bubalis), which are bred in Ukraine in the household of Sviato-Pokrovska Holosiivska Pustyn monastery ...
Valentyna Dzitsiuk, Tetyana Ryk, Tamara Lytvynenko   +2 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

A comprehensive ocular profile using multimodal imaging systems and surgical outcome in a patient with Alport syndrome

Oman Journal of Ophthalmology, 2023
Soumen Sadhu, Janarthanam Jothi Balaji, Bhaskar Srinivasan   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source