Results 71 to 80 of about 739 (181)

Chemical Evolution of Early Macromolecules: From Prebiotic Oligopeptides to Self‐Organizing Biosystems via Amyloid Formation

open access: yesChemistry – A European Journal, Volume 31, Issue 29, May 22, 2025.
APR‐A, an aggregation‐prone oligopeptide, can convert into APR‐B through distinct mutational pathways—some exclusively forming insoluble amyloid‐like peptides, others yielding water‐soluble, non‐aggregating monomers. These orthogonal pathways in chemical evolution may have driven macromolecular assembly under prebiotic Earth conditions, potentially ...
Fruzsina Bencs   +7 more
wiley   +1 more source

The Nature of Stability in Replicating Systems

open access: yesEntropy, 2011
We review the concept of dynamic kinetic stability, a type of stability associated specifically with replicating entities, and show how it differs from the well-known and established (static) kinetic and thermodynamic stabilities associated with regular ...
Addy Pross, Nathaniel Wagner
doaj   +1 more source

Effect of Alkali‐ and Alkaline‐Earth‐Metal Promoters on Silica‐Supported Co−Fe Alloy for Autocatalytic CO2 Fixation

open access: yesAngewandte Chemie, Volume 136, Issue 8, February 19, 2024.
Alkali‐ and alkaline‐earth‐metal‐promoted Co−Fe bimetallic catalysts on silica can convert CO2 and H2O to crucial metabolites such as formate, acetate, pyruvate as well as hydrocarbons under mild hydrothermal vent conditions. With alkali‐ and alkaline‐earth metals abundant in hydrothermal vents, our study simulates how the geochemical process can fix ...
Youngdong Song   +2 more
wiley   +2 more sources

Evaluation of antiobesogenic properties of fermented foods: In silico insights

open access: yesJournal of Food Science, Volume 90, Issue 3, March 2025.
Abstract Obesity prevalence has steadily increased over the past decades. Standard approaches, such as increased energy expenditure, lifestyle changes, a balanced diet, and the use of specific drugs, are the conventional strategies for preventing or treating the disease and its associated complications.
Abdullahi Adekilekun Jimoh   +1 more
wiley   +1 more source

IR SPECTRAL MAPPING OF THE MARTIAN SOUTH POLAR RESIDUAL CAP USING CRISM [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2016
Polycyclic aromatic hydrocarbons (PAHs) are considered to be important in theories of abiogenesis (Allamandola, 2011) . There is evidence that PAHs have been detected on two icy Saturnian satellites using the Visual and Infrared Mapping Spectrometer ...
J. Campbell   +3 more
doaj   +1 more source

Step‐by‐Step Towards Biological Homochirality – from Prebiotic Randomness To Perfect Asymmetry

open access: yesChemistry – An Asian Journal, Volume 20, Issue 1, January 2, 2025.
This review focuses on the theories related to the emergence of biological homochirality, from assembly of building blocks at the monomer level, to polymerization into functional homochiral biopolymers. Abstract The history of life's formation and the origin of its stereochemistry are nearly as multifaceted as the life itself.
Ivana Mejdrová   +2 more
wiley   +1 more source

Factoring Origin of Life Hypotheses into the Search for Life in the Solar System and Beyond

open access: yesLife, 2020
Two widely-cited alternative hypotheses propose geological localities and biochemical mechanisms for life’s origins. The first states that chemical energy available in submarine hydrothermal vents supported the formation of organic compounds and ...
Alex Longo, Bruce Damer
doaj   +1 more source

Bacterial Utilisation of Aliphatic Organics: Is the Dwarf Planet Ceres Habitable?

open access: yesLife, 2022
The regolith environment and associated organic material on Ceres is analogous to environments that existed on Earth 3–4 billion years ago. This has implications not only for abiogenesis and the theory of transpermia, but it provides context for ...
Sahan A. Jayasinghe   +3 more
doaj   +1 more source

The evolution and history of Vinca alkaloids: From the Big Bang to the treatment of pediatric acute leukemia

open access: yesPediatric Blood &Cancer, Volume 71, Issue 11, November 2024.
Abstract An attractive flower from the island of Madagascar has in part saved the lives of thousands of children with acute lymphoblastic leukemia (ALL). Random mutations and alterations to the genome led to the evolution of genes encoding enzymes, which would provide the periwinkle flower an arsenal of secondary metabolites to survive within the ...
Jeffrey W. Taub   +5 more
wiley   +1 more source

The remarkable cell: Intelligently designed or by evolutionary process?

open access: yesVerbum et Ecclesia, 2013
The objective of this article was to deal with the challenging theme of the Origin of Life. Science has been arguing the when and how of the beginning of life for centuries.
Mark Pretorius
doaj   +1 more source

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