Results 71 to 80 of about 739 (181)
APR‐A, an aggregation‐prone oligopeptide, can convert into APR‐B through distinct mutational pathways—some exclusively forming insoluble amyloid‐like peptides, others yielding water‐soluble, non‐aggregating monomers. These orthogonal pathways in chemical evolution may have driven macromolecular assembly under prebiotic Earth conditions, potentially ...
Fruzsina Bencs+7 more
wiley +1 more source
The Nature of Stability in Replicating Systems
We review the concept of dynamic kinetic stability, a type of stability associated specifically with replicating entities, and show how it differs from the well-known and established (static) kinetic and thermodynamic stabilities associated with regular ...
Addy Pross, Nathaniel Wagner
doaj +1 more source
Alkali‐ and alkaline‐earth‐metal‐promoted Co−Fe bimetallic catalysts on silica can convert CO2 and H2O to crucial metabolites such as formate, acetate, pyruvate as well as hydrocarbons under mild hydrothermal vent conditions. With alkali‐ and alkaline‐earth metals abundant in hydrothermal vents, our study simulates how the geochemical process can fix ...
Youngdong Song+2 more
wiley +2 more sources
Evaluation of antiobesogenic properties of fermented foods: In silico insights
Abstract Obesity prevalence has steadily increased over the past decades. Standard approaches, such as increased energy expenditure, lifestyle changes, a balanced diet, and the use of specific drugs, are the conventional strategies for preventing or treating the disease and its associated complications.
Abdullahi Adekilekun Jimoh+1 more
wiley +1 more source
IR SPECTRAL MAPPING OF THE MARTIAN SOUTH POLAR RESIDUAL CAP USING CRISM [PDF]
Polycyclic aromatic hydrocarbons (PAHs) are considered to be important in theories of abiogenesis (Allamandola, 2011) . There is evidence that PAHs have been detected on two icy Saturnian satellites using the Visual and Infrared Mapping Spectrometer ...
J. Campbell+3 more
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Step‐by‐Step Towards Biological Homochirality – from Prebiotic Randomness To Perfect Asymmetry
This review focuses on the theories related to the emergence of biological homochirality, from assembly of building blocks at the monomer level, to polymerization into functional homochiral biopolymers. Abstract The history of life's formation and the origin of its stereochemistry are nearly as multifaceted as the life itself.
Ivana Mejdrová+2 more
wiley +1 more source
Factoring Origin of Life Hypotheses into the Search for Life in the Solar System and Beyond
Two widely-cited alternative hypotheses propose geological localities and biochemical mechanisms for life’s origins. The first states that chemical energy available in submarine hydrothermal vents supported the formation of organic compounds and ...
Alex Longo, Bruce Damer
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Bacterial Utilisation of Aliphatic Organics: Is the Dwarf Planet Ceres Habitable?
The regolith environment and associated organic material on Ceres is analogous to environments that existed on Earth 3–4 billion years ago. This has implications not only for abiogenesis and the theory of transpermia, but it provides context for ...
Sahan A. Jayasinghe+3 more
doaj +1 more source
Abstract An attractive flower from the island of Madagascar has in part saved the lives of thousands of children with acute lymphoblastic leukemia (ALL). Random mutations and alterations to the genome led to the evolution of genes encoding enzymes, which would provide the periwinkle flower an arsenal of secondary metabolites to survive within the ...
Jeffrey W. Taub+5 more
wiley +1 more source
The remarkable cell: Intelligently designed or by evolutionary process?
The objective of this article was to deal with the challenging theme of the Origin of Life. Science has been arguing the when and how of the beginning of life for centuries.
Mark Pretorius
doaj +1 more source