Results 121 to 130 of about 9,574,494 (334)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Preparation of SiC/TiC composite ceramics by precursor conversion method and their oxy-propane ablation behavior at 1600 ℃

Journal of Aeronautical Materials
To address the issues of volatile oxide scale and insufficient oxidation/ablation resistance of monolithic SiC ceramics in extreme environments，this study employs polysiloxane as a ceramic precursor and titanium acetylacetonate (TiO(acac)2) as a modifier.
CAO Yongbo, ZHANG Yulei, HU Xinyi, FU Yanqin, LI Hejun   +4 more
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Research progress in ablative resistant ethylene■propylene■diene terpolymer

Hecheng xiangjiao gongye
Ethylene■propylene■diene terpolymer （EPDM） was a new type of ablation■resistant matrix material with low density, good thermal stability and excellent ablation resistance, and it found extensive applications in aerospace, thermal protection and other ...
ZHAO Dong-wei1, WEN Yan-wei2, FU Quan-sheng1, CHEN Meng-han1, YANG Zi-fan1, JIA Hong-bing1
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Preparation, oxidation and ablation resistance of IrAl intermetallic coating [PDF]

, 2017
Iridium (Ir) has been selected as the protective coating on the rhenium thruster chamber of the liquid rocket engine, due to its high melting point, excellent corrosion resistance and quite low oxygen permeability. However, Ir forms gaseous oxides rather
Zhu, Li’an, Bai, Shuxin, Zhang, Hong, Ye, Yicong   +3 more
core   +1 more source

"Hysteroscopic ablation of Choriocarcinoma in a patient resistant to chemotherapy "

Acta Medica Iranica, 2000
Gestational Trophoblastic Neoplasia ( GTN) is one of the most common gynecologic tumors in our country. Despite development of effective chemotherapy: some cases remain resistant and if there is only focus of tumor, resection would be indicated.We present a young woman with stage 1 persistant GTN showing no response to chemotherapy.
Ghazizadeh S, Behtash N, Ghaem Maghami F, Modares M, Moosavi A   +4 more
openaire   +2 more sources

CO2 Laser Ablation Area Scaling and Redeposition on Flat Polyoxymethylene Targets [PDF]

, 2010
One of the remaining subjects of interest for laser ablation propulsion study is whether special benefits or challenges exist when applying a particularly large or small laser spot area to a target. This subject is of high importance for topics including
Sinko, John Elihu, Eckel, Hans-Albert, Sasoh, Akihiro, Scharring, Stefan, Ogita, Naoya, Röser, Hans-Peter   +5 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source