Results 81 to 90 of about 99,877 (298)

Ablation resistant ZrC coating modified by polymer-derived SiC/TiC nanocomposites for ultra-high temperature application

open access: yes, 2022
To improve the ablation resistance of ZrC coating on SiC-coated carbon/carbon composites above 2000 °C, SiC/TiC nanocomposites (SiC/TiC-NCs) powders derived from single-source precursor were incorporated into ZrC coating, denoted as ZrC-SiC/TiC-NCs, via ...
Fu, Qiangang   +5 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Multipronged Design of Light-Triggered Nanoparticles To Overcome Cisplatin Resistance for Efficient Ablation of Resistant Tumor

open access: yes, 2015
Chemotherapeutic drugs frequently encounter multiple drug resistance in the field of cancer therapy. The strategy has been explored with limited success for the ablation of drug-resistant tumor via intravenous administration. In this work, the rationally
Yibin Deng (410103)   +10 more
core   +1 more source

Role of Apolipoprotein D and Its Homologs, in Normal and Pathological Aging, in Drosophila melanogaster [PDF]

open access: yes, 2009
The free radical theory of aging is probably the most enduring one to date. It stipulates that, in the process of normal cellular function, in particular due to oxygen-based respiration, reactive oxygen species are formed.
Muffat, Julien A.
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Fabrication, Microstructural Characterization, and Ablation Behavior of a Novel 3D Orthogonal Woven C/C-SiC-ZrB2 Composite Through I-CVI, SI, and LSI Combined Processes [PDF]

open access: yesIranian Journal of Materials Science and Engineering
This paper presents the novel fabrication method of a three-dimensional orthogonally woven (3DW) C/C-SiC-ZrB2 composite and the effects of ZrB2 and SiC particles on microstructure and the ablation behavior of the C/C–SiC–ZrB2 composite are studied.
Amin Rezaei Chekani   +3 more
doaj  

The effect of nitrogen doping on the ablation resistance of zirconium carbide ceramics

open access: yesJournal of Advanced Ceramics
Ultrahigh-temperature ceramics (UHTCs) are prominent candidates for use in thermal protection systems in the aerospace and nuclear industries. This study introduces a nitrogen-doped zirconium carbide that demonstrates remarkable ablation resistance ...
Zheng Peng   +5 more
doaj   +1 more source

Ablation-resistant carbide Zr0.8Ti0.2C0.74B0.26 for oxidizing environments up to 3,000 °C

open access: yesNature Communications, 2017
Hypersonic and aerospace applications motivate development of materials with improved resistance against ablation and oxidation at high temperatures. Here authors demonstrate a quaternary carbide, where sealing by surface oxides, slow oxygen diffusion ...
Yi Zeng   +8 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

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