Results 71 to 80 of about 9,574,494 (334)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Ablation-Resistance of Combustion Synthesized TiB2–Cu Cermet [PDF]

open access: yes, 2004
TiB2–Cu ceramic–metal composites were prepared by combustion\ud synthesis of elemental titanium, boron, and copper powders.\ud The synthesized product consisted of two phases: TiB2 and\ud copper.
Xu, Qiang   +11 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Preparation and Properties of Magnetically Responsive Graphene/Boron Nitride/Iron Oxide Filler Composite Epoxy Resin Materials

open access: yesNanomaterials
In this paper, magnetically responsive graphene/boron nitride/iron oxide fillers were prepared by growing iron oxide on the surface of graphene/boron nitride fillers via liquid-phase reaction.
Yiheng Yu   +4 more
doaj   +1 more source

Preparation of Silicon Rubber/2,2'-(3-methyl-4-dihydro-1,3,2-benzoxazine)Propane Ablative-resistant Composites and Its Ablative Structure

open access: yesJournal of Aeronautical Materials, 2017
Benzoxazine resin is a new generation of anti-ablation resin with high char yield and high-temperature oxidation resistance. Using high temperature vulcanized silicon rubber as ablation resistance matrix and 2,2'-(3-methyl-4-dihydro-1,3,2-benzoxazine ...
DONG Yimin, YIN Zhengshuai, LI Yong
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

On testing laser ablation processes for asteroid deflection [PDF]

open access: yes, 2011
Laser surface ablation has been theoretically demonstrated to be an advantageous method in the potential mitigation and deflection of Near Earth Asteroids.
Burns, David   +3 more
core   +2 more sources

Absorption waves produced by CO2 laser ablation [PDF]

open access: yes, 2006
A requirement for efficient pulsed laser propulsion from ground to LEO is the achievement of a specific impulse of up to 800 s at a jet efficiency of at least 50%.
Schall, Wolfgang   +2 more
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Supranational surveillance of antimicrobial resistance: The legacy of the last decade and proposals for the future

open access: yes, 2010
Antimicrobial resistance among clinically important bacteria is widely acknowledged as a major global public health threat. A decade ago, several supranational surveillance initiatives were introduced. Few of them are still ongoing, and only one features
CORNAGLIA, Giuseppe   +6 more
core   +1 more source

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