Results 21 to 30 of about 1,088,189 (289)

Drug Exposure During Pregnancy: A Case-Control Study from a Primary Care Database

Women's Health Reports
Objective: Drug exposure during pregnancy is frequent, even more during first trimester as pregnant women might not be aware of their condition. We used available electronic health records (EHRs) to describe the use of medications during the first ...
Ainhoa Gomez-Lumbreras, Marta Leston Vazquez, Carles Vilaplana-Carnerero, Oriol Prat-Vallverdu, Cristina Vedia, Rosa Morros, Maria Giner-Soriano   +6 more
doaj   +3 more sources

EFFECT OF LONG TERM ADMINISTRATION OF CARROT ROOTS (Daucus carota) ON SOME CYTOGENETIC PARAMETERS IN WHITE MICE [PDF]

Mesopotamia Journal of Agriculture, 2009
The effect of long term administration of carrot roots (2 months) on some cytogenetic parameters in bone marrow cells of white mice was studied , these included , mitotic index (MI) , micronuclei formation (Mn ) , and chromosomal aberrations (Ch .
Ilham A. Khalaf
doaj   +1 more source

Differential Treatments Based on Drug-induced Gene Expression Signatures and Longitudinal Systemic Lupus Erythematosus Stratification

Scientific Reports, 2019
Systemic lupus erythematosus (SLE) is a heterogeneous disease with unpredictable patterns of activity. Patients with similar activity levels may have different prognosis and molecular abnormalities. In this study, we aimed to measure the main differences
D. Toro-Domínguez, R. López-Domínguez, Adrián García Moreno, J. Villatoro-García, Jordi Martorell-Marugán, D. Goldman, M. Petri, D. Wojdyla, B. Pons-Estel, D. Isenberg, Gabriela Morales-Montes de Oca, M. Trejo-Zambrano, Benjamín García González, F. Rosetti, D. Gómez-Martín, J. Romero-Díaz, P. Carmona-Sáez, M. Alarcón-Riquelme   +17 more
semanticscholar   +1 more source

Severe drug-induced liver injury associated with prolonged use of Linezolid [PDF]

, 2010
This study aims to describe a patient developing concomitant severe liver failure and lactic acidosis after long-term treatment with linezolid. A 55-year-old Caucasian woman developed concomitant severe liver failure and lactic acidosis after a treatment
Benoit, Dominique, De Bus, Liesbet, Depuydt, Pieter, Libbrecht, Louis, NOLLET, JOKE, Van Vlierberghe, Hans, Vandekerckhove, Linos, Vogelaers, Dirk   +7 more
core   +1 more source

Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro-Arrhythmic Cardiotoxicity

Frontiers in Physiology, 2017
Early prediction of cardiotoxicity is critical for drug development. Current animal models raise ethical and translational questions, and have limited accuracy in clinical risk prediction.
Elisa Passini, Oliver J. Britton, Hua Rong Lu, Jutta Rohrbacher, An N. Hermans, David J. Gallacher, Robert J. H. Greig, Alfonso Bueno-Orovio, Blanca Rodriguez   +8 more
doaj   +1 more source

EFFECT OF LONG TERM ADMINISTRATION OF CARROT ROOTS (Daucus carota) ON SOME CYTOGENETIC PARAMETERS IN WHITE MICE [PDF]

Mesopotamia Journal of Agriculture, 2010
The effect of long term administration of carrot roots (2 months) on some cytogenetic parameters in bone marrow cells of white mice was studied , these included , mitotic index (MI) , micronuclei formation (Mn ) , and chromosomal aberrations (Ch .
Ilham A. Khalaf
doaj   +1 more source

Neuroimaging Techniques in Differentiating Parkinson’s Disease from Drug-Induced Parkinsonism: A Comprehensive Review

Clinics and Practice, 2023
Neuroimaging can provide significant benefits in evaluating patients with movement disorders associated with drugs. This literature review describes neuroimaging techniques performed to distinguish Parkinson’s disease from drug-induced parkinsonism.
Jamir Pitton Rissardo, Ana Letícia Fornari Caprara   +1 more
doaj   +1 more source

Recent Advances in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms

Journal of Immunological Research, 2018
Drug-induced hypersensitivity syndrome (DIHS), also termed as drug reaction with eosinophilia and systemic symptoms (DRESS), is a multiorgan systemic reaction characterized by a close relationship with the reactivation of herpes virus. Published data has
Hideaki Watanabe
semanticscholar   +1 more source

Antipsychotics and Torsadogenic Risk: Signals Emerging from the US FDA Adverse Event Reporting System Database [PDF]

, 2013
Background: Drug-induced torsades de pointes (TdP) and related clinical entities represent a current regulatory and clinical burden. Objective: As part of the FP7 ARITMO (Arrhythmogenic Potential of Drugs) project, we explored the publicly available US ...
A Bate, A Clarke, A Pariente, AK Chung, Ariola Koci, B Darpo, BJ Drew, C Meyer-Massetti, DM Roden, DW Hough, E Poluzzi, E Poluzzi, E Poluzzi, E Raschi, E Raschi, Edoardo Spina, Elijah R. Behr, Elisabetta Poluzzi, Emanuel Raschi, EP Puijenbroek van, ER Behr, F Ponti De, F Ponti De, F Rani, Fabrizio De Ponti, GC Alexander, GK Isbister, H Verdoux, J Nielsen, J Papay, K Jolly, K Titier, LC Wittkampf, LS Schneider, Miriam Sturkenboom, NP Tatonetti, P Kannankeril, P Manu, P Vigneault, RC Owens Jr, RR Shah, S Dhillon, S Hennessy, S Kongsamut, S Leucht, SM Straus, Ugo Moretti, W Crumb, W Crumb, WA Ray, WA Ray, WJ Crumb Jr, WP Stephenson, Y Suzuki   +53 more
core   +3 more sources

Boosting autophagy in the diabetic heart: a translational perspective [PDF]

, 2015
Diabetes, obesity, and dyslipidemia are main risk factors that promote the development of cardiovascular diseases. These metabolic abnormalities are frequently found to be associated together in a highly morbid clinical condition called metabolic ...
Boppana, V. Subbarao, FRATI, GIACOMO, Sadoshima, Junichi, SCIARRETTA, SEBASTIANO, Umapathi, Mahaa   +4 more
core   +1 more source