Results 51 to 60 of about 1,088,189 (289)

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

FEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez, Cristina Velez‐delValle, Claudia Patricia Hernández‐Mosqueira, Walid Kuri‐Harcuch   +3 more
wiley   +1 more source

Modeling neurocognitive and neurobiological recovery in addiction [PDF]

, 2019
This book focuses on "what to know" and "how to apply" information, prioritizing novel principles and delineating cutting-edge assessment, phenotyping and treatment ...
Abé, Agartz, Aharonovich, Almeida, Anderson, Bae, Bates, Bernardin, Blaine, Block, Bolla, Brody, Buhler, Cardenas, Cardenas, Cavazos-Rehg, Chang, Chang, Charlet, Crews, Crews, de Wit, Demirakca, Di Sclafani, Dlugos, Dom, Dominguez-Salas, Duka, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Eldreth, Ernst, Ernst, Ernst, Ersche, Ersche, Fein, Fein, Fein, Fernandez-Serrano, Fernandez-Serrano, Franklin, Gansler, Gazdzinski, Gazdzinski, Gazdzinski, Gazdzinski, Giorgi, Glass, Goldstein, Goldstein, Hanlon, Hasin, Heinz, Hermann, Hirsiger, Hoefer, Holman, Humphreys, Hwang, Iudicello, Kalman, Ke, Kim, Klein, Koob, Le Berre, Licata, Loeber, Mackey, Matochik, Matochik, Medina, Meyerhoff, Meyerhoff, Meyerhoff, Meyerhoff, Meyerhoff, Meyerhoff, Meyerhoff, Mon, Mon, Mon, Moorman, Morales, Moreno-Alcázar, Moss, Murray, Murray, Nader, Nicolas, Nordahl, Noyan, O'Neill, Oishi, Oscar-Berman, Oscar-Berman, Parks, Parvaz, Passetti, Pennington, Pennington, Pfefferbaum, Prescot, Prescot, Rabin, Rando, Rezapour, Rogers, Rourke, Rupp, Sailasuta, Salo, Schmidt, Schulte, Segobin, Seo, Seo, Simon, Sneider, Sorg, Stavro, Stevens, Streeter, Sullivan, Sullivan, Sullivan, Sullivan, Thompson, Tunving, van Eijk, Verdejo-Garcia, Verdejo-Garcia, Verdejo-Garcia, Volkow, Volkow, Volkow, Volkow, Volkow, Volkow, Volkow, Volkow, Vonmoos, Walitzer, Wang, Wang, Wang, Weber, Weinberger, Weinberger, Weinberger, Williams, Witkiewitz, Xiao, Yang, Yeh, Yoon, Younger, Yucel, Zahr, Zahr, Zatorre, Zou   +179 more
core   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Childhood maltreatment and amygdala connectivity in methamphetamine dependence: a pilot study. [PDF]

, 2014
IntroductionChildhood maltreatment, a well-known risk factor for the development of substance abuse disorders, is associated with functional and structural abnormalities in the adult brain, particularly in the limbic system.
Dean, Andy C, Hellemann, Gerhard, Kohno, Milky, London, Edythe D   +3 more
core   +2 more sources

Toxicology knowledge graph for structural birth defects

Communications Medicine, 2023
Background Birth defects are functional and structural abnormalities that impact about 1 in 33 births in the United States. They have been attributed to genetic and other factors such as drugs, cosmetics, food, and environmental pollutants during ...
John Erol Evangelista, Daniel J. B. Clarke, Zhuorui Xie, Giacomo B. Marino, Vivian Utti, Sherry L. Jenkins, Taha Mohseni Ahooyi, Cristian G. Bologa, Jeremy J. Yang, Jessica L. Binder, Praveen Kumar, Christophe G. Lambert, Jeffrey S. Grethe, Eric Wenger, Deanne Taylor, Tudor I. Oprea, Bernard de Bono, Avi Ma’ayan   +17 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Obstrução intestinal após uso de infliximab no tratamento de fístula êntero-cutânea na doença de Crohn

Revista do Colégio Brasileiro de Cirurgiões
Crohn's disease is often complicated by the development of fistulas. Infliximab, a monoclonal antibody that binds tumor necrosis factor a have shown to be successful in the treatment of fistulizing Crohn's disease.
Carolina Gomes Gonçalves, Júlio Cezar Uili Coelho, Heda Maria Braska dos Santos Amarante   +2 more
doaj   +1 more source

Lamotrigine hypersensitivity syndrome and spiking fever

Indian Journal of Dermatology, 2012
We report a case of a 26 year old woman with rash, lymphadenopathy, liver enzyme abnormalities and spiking fever. She was diagnosed with drug-induced hypersensitivity syndrome (DHS) to lamotrigine.
Christiaan V Bakker, Vincent Noordhoek Hegt, Marinus C G Van Praag   +2 more
doaj   +1 more source

Antifungal-Associated Drug-Induced Cardiac Disease.

Clinical Infectious Diseases, 2015
The etiology of cardiomyopathies are classified into 4 main groupings (dilated, hypertrophic, restrictive, and idiopathic) and can be mechanistically caused by myocarditis, conduction abnormalities, focal direct injury, or nutritional deficiency.
J. Cleary, Kayla R. Stover
semanticscholar   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source