Results 101 to 110 of about 77,071 (250)

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Introduction: Theory

Lateral, 2014
Lateral’s Theory Thread offers essays that critically explore the relationship of carceral and educational institutions—but not as alternatives to one another as often has been assumed in various kinds of social activism.
Patricia Picineto Clough
doaj   +1 more source

Slavery, Abolition, and Emancipation

, 2016
Les pages du site "Slavery, Abolition, and Emancipation" renvoient vers de nombreuses ressources sur l'étude de l'esclavage, de son abolition et de son émancipation.
Ginouvès, Véronique
core  

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu   +20 more
wiley   +1 more source

Six Steps to Abolishing Primary School Fees : Operational Guide

, 2009
This Operational Guide is one of the main outputs of the School Fee Abolition Initiative (SFAI). SFAI is designed to significantly advance eff orts to ensure access to quality basic education by supporting policies that remove the education cost barriers
School Fee Abolition Initiative
core   +1 more source

“My Vision Isn’t The Only One”

Journal for Social Action in Counseling and Psychology
School counseling is built on the American School Counselor Association National Model (2019, 2025), which includes heavy emphasis on individualist-focused student standards and isolationist practice (Drake et al., 2024b).
Riley Drake, Renae Mayes, Abby Smith, Ingrid Lyberg   +3 more
doaj   +1 more source

Making Anyway: Education, Designing, Abolition

Lateral, 2014
This essay aims to raise some provocations and questions about the practice of attempting to teach abolition in universities and colleges that are embracing the notion of the duty of the university to ...
Shana Agid
doaj   +1 more source

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

Abolition as Spiritual Discipline

, 2022
This paper explores abolition as a spiritual discipline, considering the possibilities of turning a political commitment into a ritual, daily practice that becomes an ethic.
Creeks, Azani Amarachi
core   +1 more source

European private law & intersectionality: three strategies

European Law Open
In this paper we identify and discuss three different strategies for taking up intersectionality in the space of European private law, ie, liberal ideal theories of social and private law justice, liberal nonideal theories of reparation, and private law ...
Martijn W Hesselink, Lyn KL Tjon Soei Len   +1 more
doaj   +1 more source