Results 41 to 50 of about 307,093 (281)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Drilled Choreographies: Interventions on Preparing for the Active Shooter
Conversations Across the Field of Dance StudiesIn the United States, safety preparation in the form of active shooter trainings are quotidian practices performed in nearly all K-12 public school systems. This paper works to understand how active shooter trainings in the U.S.
Shannon Woods
doaj +2 more sources
Abolition: At Issue, In Any Case
Lateral, 2014 Toward what does the 'prison abolitionist' identity or identification strive? This thread is organized primarily around Fred Moten and Stefano Harney’s essay, “The University and the Undercommons: Seven Theses.” And we think there is not a better place ...
Sora Han
doaj +1 more source
Economic Analysis of the Effects of the Expiry of the EU Milk Quota System [PDF]
, 2008 This report has been prepared to provide a quantitative assessment of the impact of the abolition of EU milk quotas on the EU dairy sector, including the different policy approaches of gradual phasing out and abrupt abolition of milk ...
Bouamra-Mechemache, Z. +2 more
core +2 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Identity Documents and Gender Identity: Towards Inclusive Practices
Perspective PoliticeIn a world increasingly focused on inclusivity, addressing the challenges faced by gender nonconforming and transgender individuals is crucial. Identity documents are meant to represent us, but the current approaches of administrative systems in ...
Elisabeth-Gabrielle SATALAN
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Revista Mundos do Trabalho, 2019 On 1887, a rule to discipline domestic labor in Salvador was published by the City Council. This rule provided that all the servants were to be enrolled in the Police Department, which resulted in 897 registrations, with extremely rich data, containing ...
Marina Leão de Aquino Barreto
doaj +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source