Results 61 to 70 of about 61,325 (295)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Abolition: At Issue, In Any Case
Lateral, 2014 Toward what does the 'prison abolitionist' identity or identification strive? This thread is organized primarily around Fred Moten and Stefano Harney’s essay, “The University and the Undercommons: Seven Theses.” And we think there is not a better place ...
Sora Han
doaj +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Six Steps to Abolishing Primary School Fees : Operational Guide [PDF]
, 2009 This Operational Guide is one of the main outputs of the School Fee Abolition Initiative (SFAI). SFAI is designed to significantly advance eff orts to ensure access to quality basic education by supporting policies that remove the education cost barriers
School Fee Abolition Initiative
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Contemporary ChallengesNorthern Ireland faces a growing police use of force, increased imprisonment of individuals suffering from mental ill-health, the lowest minimum age of criminality in Europe, and high reports of abuse against marginalised communities.
Nathan Johnson
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Revista Mundos do Trabalho, 2019 On 1887, a rule to discipline domestic labor in Salvador was published by the City Council. This rule provided that all the servants were to be enrolled in the Police Department, which resulted in 897 registrations, with extremely rich data, containing ...
Marina Leão de Aquino Barreto
doaj +1 more source
, 2023 When abolitionists discuss remedies for past and present injustices, they are frequently met with apparently pragmatic objections to the viability of such bold remedies in U.S. legislatures and courts held captive by reactionary forces.
Hasbrouck, Brandon
core +1 more source