Results 61 to 70 of about 77,071 (250)
Whitman, Emerson, and The Ballad of the Abolition Blunder-buss [PDF]
Contrasts Whitman\u27s and Emerson\u27s attitudes towards abolition and details the attitudes toward African-Americans that Whitman encountered in Boston; concludes by presenting a scurrilous satirical work called \u27Ballad of the Abolition Blunder ...
Gougeon, Len
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
This is a post-peer-review, pre-copy edited version of a chapter published in Envisioning Abolition. The definitive publisher-authenticated version [Cox, P. & Taylor, P (2025). Arthur St. John: Tolstoyan Abolitionism in Practice. In D. G. Scott & E. Bell
Taylor, Paul, Cox, Peter
core +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Lessons of the 1999 Abolition of Intra-EU Duty Free Sales for Eastern European EU Candidates [PDF]
At the end of June 1999 the intra-EU duty free shopping was abolished among the fifteen member nations. The opponents of this resolution argued that such a tax-free sales sector created jobs EU-wide and hardly reduced the value added and excise tax ...
Andrea Gebauer +2 more
core +2 more sources
This article examines the representation of racial violence in the work of Martín Morúa Delgado (1856–1910), focusing on his role in shaping spaces of resistance against slavery.
Miguel Ibáñez Aristondo
doaj +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source

