Results 61 to 70 of about 256,969 (396)
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Mesambria Pontica – coevolution of maritime community and coastal landscape
The study presents the changes in coastline, fortification and development of the coastal zone of the “city-peninsula” – the Classical and Hellenistic Mesambrian polis, the provincial-Roman peregrine city and the (early) Byzantine bipolar municipality ...
Hristo Preshlenov
doaj +1 more source
Vibratory Finishing of Stereolithography Parts [PDF]
Rapid Prototype polymer resin models produced by Stereolithography have, by the nature of the process, a relatively poor surface roughness, particularly on concave and convex surfaces.
Spencer, John D.
core +1 more source
Traumatic Corneal Abrasion [PDF]
Corneal abrasions can have potentially sight-threatening consequences if not accurately diagnosed and managed appropriately in the acute period. Simple corneal abrasions can be managed with antibiotic and tetanus prophylaxis, analgesia, and next-day follow up with ophthalmology.
David Lebowitz+3 more
openaire +3 more sources
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
The Use of Green Laser in LiDAR Bathymetry: State of the Art and Recent Advancements
Bathymetric LiDAR technology is a technology used for simultaneous data acquisition regarding the morphology of the bottom of water reservoirs and the surrounding coastal zone, realized from the air, e.g., by plane or drone.
Anna Szafarczyk, Cezary Toś
doaj +1 more source
A model for fluvial bedrock incision by impacting suspended and bed load sediment [PDF]
A mechanistic model is derived for the rate of fluvial erosion into bedrock by abrasion from uniform size particles that impact the bed during transport in both bed and suspended load.
Dietrich, William E.+2 more
core +1 more source
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Modification of the silicon phase and mechanical properties in Al-40Zn-6Si alloy with Eu addition
The influence of Eu additions upon the silicon phase and mechanical properties of Al-40Zn-6Si alloys have been investigated via scanning electron microscopy (SEM) and high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM ...
Feng Mao+5 more
doaj
CsF-AlF3 was added in different mass percentages to KF-AlF3 flux, and CsF-AlF3/KF-AlF3 mixed fluxes with different components were prepared by ball milling. The melting curves of four kinds of fluxes were measured using differential scanning calorimetry (
Yinkai Shi+12 more
doaj