Results 61 to 70 of about 201,555 (341)

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Selection of an Optimal Abrasion Wheel Type for Nano-Coating Wear Studies under Wet or Dry Abrasion Conditions

Nanomaterials, 2020
Nanocoatings have numerous potential applications in the indoor environment, such as flooring finishes with increased scratch- and wear-resistance. However, given concerns about the potential environmental and human health effects of nanomaterials, it is
Li-Piin Sung, Yu-Fan Chung, David G. Goodwin, Elijah J. Petersen, Hsiang-Chun Hsueh, Paul Stutzman, Tinh Nguyen, Treye Thomas   +7 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Multiphase-based predictive framework construction of abrasive wear performance in C–V–Cr–Mo alloys

Journal of Materials Research and Technology
Abrasive wear persists as the dominant failure mechanism in crushing equipment, driving the demand for predictive models to guide wear-resistant alloy design and equipment lifespan assessment.
Tao Jiang, Xuke Yao, Mengmeng Ma, Hua Yu, Junjie Sun, Yuanguang Liu, Xuezhong Hu, Chong Chen, Chunhua Lei, Xiaodong Wang   +9 more
doaj   +1 more source

Improvement and In-Situ Application of an Evaluation Method of Ballasted-Track Condition Using Digital 2-D Image Analysis

Applied Sciences, 2020
The advancement in digital image analysis methods has led to the development of various techniques, i.e., quantification of ballast gravel abrasion. In this study, the recognition rate of gravel aggregates has been significantly increased by improving ...
Bongsik Park, Yeong-Tae Choi, Hyunmin Kim   +2 more
doaj   +1 more source

A model for projectile fragmentation

, 2013
A model for projectile fragmentation is developed whose origin can be traced back to the Bevalac era. The model positions itself between the phenomenological EPAX parametrization and transport models like "Heavy Ion Phase Space Exploration" (HIPSE) model
Albergo S, Chaudhuri G, G Chaudhuri, Lynn J E, S Das Gupta, S Mallik   +5 more
core   +1 more source

A model for fluvial bedrock incision by impacting suspended and bed load sediment [PDF]

, 2008
A mechanistic model is derived for the rate of fluvial erosion into bedrock by abrasion from uniform size particles that impact the bed during transport in both bed and suspended load.
Dietrich, William E., Lamb, Michael P., Sklar, Leonard S.   +2 more
core   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

The Influence of Alumina Airborne-Particle Abrasion on the Properties of Zirconia-Based Dental Ceramics (3Y-TZP) [PDF]

, 2023
Paulina Łagodzińska, Beata Dejak, Bartłomiej Konieczny   +2 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source