Gain of function mutants: Ion channels and G protein-coupled receptors [PDF]
, 2000 Many ion channels and receptors display striking phenotypes for gain-of-function mutations but milder phenotypes for null mutations. Gain of molecular function can have several mechanistic bases: selectivity changes, gating changes including constitutive
Karschin, Andreas, Lester, Henry A.
core +1 more source
Long‐Term Stable Subdural Recordings Enabled by Fibrosis‐Resistant Hydrogel‐Integrated µECoG Arrays
Advanced Science, EarlyView.An adhesive hydrogel‐integrated micro‐electrocorticography (aGel‐µECoG) array is developed to ensure stable neural recordings by minimizing neuroinflammation and fibrosis during implantation. The hydrogel serves as a biological and mechanical bridge, enabling bioadhesive, reversible, anti‐fibrotic integration with brain tissue.
Lin Chen +13 more
wiley +1 more source
Neuromorphic Computing with Memcapacitors: Advancements, Challenges, and Future Directions
Advanced Electronic Materials, EarlyView.Neuromorphic computing reduces energy costs by integrating memory and processing in event‐driven architectures, achieving energy usage as low as 10–30 pJ per operation for memcapacitor‐based synapses. Memcapacitors are reviewed as strong contenders for neuromorphic computing, enhancing AI acceleration through charge‐based computations, high resistance,
Nada AbuHamra +4 more
wiley +1 more source
Solving the Socratic Problem—A Contribution from Medicine [PDF]
, 2018 This essay provides a medical theory that could clarify enigmas surrounding the historical Socrates. It offers textual evidence that Socrates had temporal lobe epilepsy and that its two types of seizure manifested as recurrent voices and peculiar ...
Muramoto, Osamu
core
Pushing Biomolecule Detection Limit With Graphene Field‐effect Transistor Biosensors
Advanced Electronic Materials, EarlyView.Graphene knows your health! This work presents a comprehensive overview of recent advances in graphene field‐effect transistor (GFET) biosensors for ultrasensitive biomolecule detection. How device engineering, high‐mobility graphene synthesis, and tailored surface chemistry push detection limits is highlighted, while discussing emerging strategies ...
Co Dang Pham +4 more
wiley +1 more source
Scientific and practical conference “Absence epilepsy”
Русский журнал детской неврологии.
article Editorial
doaj +1 more source
Idiopathic generalised epilepsy in adults manifested by phantom absences, generalised tonic-clonic seizures, and frequent absence status [PDF]
, 1998 Thomas P. Bleck +4 more
openalex +1 more source
Are Absence Epilepsy and Nocturnal Frontal Lobe Epilepsy System Epilepsies of the Sleep/Wake System?
Behavioural Neurology, 2015 System epilepsy is an emerging concept interpreting major nonlesional epilepsies as epileptic dysfunctions of physiological systems. I extend here the concept of reflex epilepsy to epilepsies linked to input dependent physiological systems.
P. Halász
semanticscholar +1 more source
Intelligent Supportive System for People with Profound Intellectual and Multiple Disabilities
Advanced Intelligent Systems, EarlyView.A holistic INSENSION system is developed—a novel intelligent decision support system leveraging state‐of‐the‐art noninvasive audio‐visual sensor technologies together with machine learning algorithms and expert knowledge, to detect and interpret behaviors and communications (nonverbal signals—NVSs) of people with PIMD in challenging real‐world ...
Gašper Slapničar +10 more
wiley +1 more source