Results 141 to 150 of about 2,104,112 (314)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Trends in Absolute Poverty in Pakistan: 1990-91 and 2001 [PDF]

open access: yes
Poverty, defined comprehensively as absence of options to shape one’s life according to one’s own preferences, comes closer to the concept of human development as presented in UNDP’s Human Development Reports.
Talat Anwar, Sarfraz K. Qureshi
core  

Wplątanie. Derridiańska demaskacja funkcji figury „Boga” w metafizyce obecności

open access: yesStudia Philosophica Wratislaviensia
This article is a systematic analysis of Derrida’s concept of deconstruction in terms of its critical implications regarding the function of the concept of „God” in Western theology.
Bartosz Bednarczyk
doaj   +1 more source

Absolute spectrofluorometry

open access: yesJournal of Research of the National Bureau of Standards Section A: Physics and Chemistry, 1972
The last 10 years has seen the increasing publication of the emission spectra of organic, inorganic and metal-chelate compounds, but there is no agreed method of presentation of such spectra. In the few cases where corrected emission spectra have been published, there is often no mention of the units used for the intensity coordinate or the method used
openaire   +2 more sources

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

The Relevance of Irrelevance: Absolute Objects and the Jones-Geroch Dust Velocity Counterexample, with a Note on Spinors [PDF]

open access: yes, 2005
James L. Anderson analyzed the conceptual novelty of Einstein's theory of gravity as its lack of ``absolute objects.'' Michael Friedman's related concept of absolute objects has been criticized by Roger Jones and Robert Geroch for implausibly admitting ...
Pitts, J. Brian, J. Brian Pitts
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Atoms in intense ultrashort laser pulses and the absolute phase [PDF]

open access: yes, 2004
Diese Arbeit beschäftigt sich mit der experimentellen Analyse atomarer Prozesse in intensiven ultrakurzen Laserpulsen. Der Schwerpunkt liegt hierbei bei den Zwillingseffekten der Erzeugung hoher Harmonischer (``high-order harmonic generation'', HHG) und ...
Lindner, F., Lindner, Fabrizio
core  

The Idea of Absolute in a World of Law

open access: yesEIRP Proceedings, 2011
The approach the author has the feature of an essay and he starts from the idea that the meaning ofthe absolute is found necessarily within the relative borders, to which it appears as a human representation ofdisappointment and unconditional model ...
Ioan Huma
doaj  

Home - About - Disclaimer - Privacy