Results 1 to 10 of about 92,541 (304)

Mediation and longitudinal analysis to interpret the association between clozapine pharmacokinetics, pharmacogenomics, and absolute neutrophil count [PDF]

Schizophrenia, 2023
Clozapine is effective at reducing symptoms of treatment-resistant schizophrenia, but it can also induce several adverse outcomes including neutropenia and agranulocytosis. We used linear mixed-effect models and structural equation modelling to determine
Siobhan K. Lock, Sophie E. Legge, Djenifer B. Kappel, Isabella R. Willcocks, Marinka Helthuis, John Jansen, James T. R. Walters, Michael J. Owen, Michael C. O’Donovan, Antonio F. Pardiñas   +9 more
doaj   +7 more sources

Absolute neutrophil count by Duffy status among healthy Black and African American adults. [PDF]

Blood Adv, 2023
AbstractMany people of African ancestry have lower absolute neutrophil counts (ANCs) without increased risk for infection. This is associated with the Duffy-null phenotype (nonexpression of the Duffy antigen on red blood cells), which is commonly found in those of African descent. Currently, there are no studies that compare the ANC of individuals with
Merz LE, Story CM, Osei MA, Jolley K, Ren S, Park HS, Yefidoff Freedman R, Neuberg D, Smeland-Wagman R, Kaufman RM, Achebe MO.   +10 more
europepmc   +5 more sources

Associations between absolute neutrophil count and lymphocyte-predominant breast cancer [PDF]

Breast, 2020
Introduction: Tumor-infiltrating lymphocytes (TILs) might be associated with host-cell mediated immunity, which could be partly reflected by peripheral blood cell counts.
Chang Ik Yoon, Soeun Park, Yoon Jin Cha, Hye Sun Lee, Soong June Bae, Chihwan Cha, Da Young Lee, Sung Gwe Ahn, Joon Jeong   +8 more
doaj   +8 more sources

Absolute Neutrophil Count and Mean Platelet Volume in the Blood as Biomarkers to Detect Lung Cancer. [PDF]

Dis Markers, 2020
Objective. Inflammation plays an extremely considerable role in the development and progression of malignancies. Absolute neutrophil count (ANC) and mean platelet volume (MPV) in blood are associated with various inflammatory conditions and resulted in independent prognostic factors for lung cancer.
Zhu X, Chen Y, Cui Y.
europepmc   +4 more sources

Evaluation of Absolute Neutrophil Count in the Perioperative Setting of Sarcoma Resection [PDF]

Advances in Orthopedics
Introduction. Limb salvage surgery (LSS) is the preferred surgical treatment for bone sarcomas. Preoperatively, many patients receive chemotherapy and may develop neutropenia.
Gayathri Vijayakumar, Emma M. Steffer, Neil P. Buac, Matthew W. Colman, Steven Gitelis, Alan T. Blank   +5 more
doaj   +4 more sources

Association Between Absolute Neutrophil Count and Variation at TCIRG1: The NHLBI Exome Sequencing Project. [PDF]

Genet Epidemiol, 2016
ABSTRACTNeutrophils are a key component of innate immunity. Individuals with low neutrophil count are susceptible to frequent infections. Linkage and association between congenital neutropenia and a single rare missense variant in TCIRG1 have been reported in a single family.
Rosenthal EA, Makaryan V, Burt AA, Crosslin DR, Kim DS, Smith JD, Nickerson DA, Reiner AP, Rich SS, Jackson RD, Ganesh SK, Polfus LM, Qi L, Dale DC, University of Washington, Center for Mendelian Genomics, Jarvik GP.   +16 more
europepmc   +8 more sources

Insulin resistance in school-aged girls with overweight and obesity is strongly associated with elevated white blood cell count and absolute neutrophil count [PDF]

Frontiers in Endocrinology, 2022
BackgroundThe primary objective of the study was to discuss the sex differences in insulin resistance-induced changes in metabolic and inflammatory markers in school-aged children with overweight and obesity.MethodsA cross-sectional study of 800 children
Hong-Mei He, Lu Zhang, Lu Zhang, Lu Zhang, Na Qiu, Ze-Tao Zhou, Ka Zhang, Yan Li, Hao-Bo Chen, Jia-Ning Xu   +9 more
doaj   +2 more sources

Prognostic significance of absolute lymphocyte count, absolute neutrophil count, and neutrophil-to-lymphocyte ratio in COVID-19

Journal of Marine Medical Society, 2021
Introduction: Effective triage of COVID-19 patients, especially in resource-limited settings, requires cost-effective and readily available markers. The present study looks at the prognostic role of three such laboratory parameters, absolute lymphocyte ...
K V Padmaprakash, Kuldeep Kumar Ashta, Nishant Raman, Vasu Vardhan, Sandeep Thareja, J Muthukrishnan, K S Rajmohan, Sudhir Dubey, Dheeraj Nauhwaar, Abhinav Kumar, P Basavaraj   +10 more
doaj   +3 more sources

Absolute neutrophil count nadir in healthy pediatric patients with the Duffy-null phenotype. [PDF]

Blood Adv, 2023
Merz LE, Li SH, Ney G, Michniacki TF, Hannibal MC, Walkovich KJ.   +5 more
europepmc   +5 more sources

Low Absolute Neutrophil Counts in African Infants [PDF]

Journal of the International Association of Physicians in AIDS Care, 2005
Infants of African origin have a lower normal range of absolute neutrophil counts than white infants; this fact, however, remains under appreciated by clinical researchers in the United States. During the initial stages of a clinical trial in Malawi, the authors noted an unexpectedly high number of infants with absolute neutrophil counts that would be
Athena P. Kourtis, Brian Bramson, Charles van der Horst, Peter N. Kazembe, Yusuf Ahmed, Charles Chasela, Mina C. Hosseinipour, R. J. Knight, Lebah Lugalia, Gerald Tegha, George Joaki, Robert Jafali, Denise J. Jamieson   +12 more
openalex   +4 more sources