Results 211 to 220 of about 175,779 (327)

Immuno‐haemostatic dysregulation in heart failure with preserved ejection fraction

ESC Heart Failure, EarlyView.
Abstract Aims Heart failure with preserved ejection fraction (HFpEF) is a complex condition with partially unclear pathophysiology, in which systemic inflammation is a central contributor to changes in cardiac structure and function. The contribution of non‐traditional immune effectors—such as platelets and coagulation—remains underexplored in HFpEF ...
Giorgia D'Italia, Daniëlle M. Coenen, Titus P. Lemmens, Lloyd Brandts, Simone J. H. Wielders, Magdolna Nagy, Sanne G. J. Mourmans, Anouk Achten, Ahmad Al‐Abadi, Jerremy Weerts, Arantxa Barandiaran Aizpurua, Vanessa van Empel, Blanche Schroen, Judith M. E. M. Cosemans   +13 more
wiley   +1 more source

Quantification of Radiation Injury on Neutropenia and the Link between Absolute Neutrophil Count Time Course and Overall Survival in Nonhuman Primates Treated with G-CSF. [PDF]

Pharm Res, 2020
Harrold J, Gisleskog PO, Delor I, Jacqmin P, Perez-Ruixo JJ, Narayanan A, Doshi S, Chow A, Yang BB, Melhem M.   +9 more
europepmc   +1 more source

Prognostic significance of somatic mutations in myeloid cells of men with chronic heart failure – interaction between loss of Y chromosome and clonal haematopoiesis

European Journal of Heart Failure, EarlyView.
Abstract Aims Age‐associated clonal haematopoiesis of indeterminate potential (CHIP) has been linked to increased incidence and worse prognosis of chronic heart failure (CHF). CHIP arises from somatic mutations in haematopoietic stem and progenitor cells. Mosaic loss of Y chromosome (LOY), the most common somatic mutation in male blood cells, increases
Sebastian Cremer, Moritz von Scheidt, Klara Kirschbaum, Lukas Tombor, Silvia Mas‐Peiro, Wesley Abplanalp, Tina Rasper, Akshay Ware, Andrin Schuff, Alexander Berkowitsch, Johannes Krefting, David Leistner, Heribert Schunkert, Thimoteus Speer, Stefanie Dimmeler, Andreas Michael Zeiher   +15 more
wiley   +1 more source

Associations between the gut microbiota, immune cells, and different subtypes of epilepsy: A Mendelian randomization study

Epilepsia Open, EarlyView.
Abstract Objective The gut microbiota (GM) plays a role in epilepsy development via the microbiota–gut–brain axis. However, its relationship with various epilepsy subtypes and its mediating role through immune cells remain unclear. Thus, identifying the GM linked to specific epilepsy subtypes and investigating immune mechanisms to predict epilepsy risk,
Xu Zhang, Zhenlin Yang, Jingjing Guo, Yuanxin Wei, Jinzi Li   +4 more
wiley   +1 more source

The Role of Machine Learning to Detect Occult Neck Lymph Node Metastases in Early‐Stage (T1‐T2/N0) Oral Cavity Carcinomas

Head &Neck, EarlyView.
ABSTRACT Objective Oral cavity carcinomas (OCCs) represent roughly 50% of all head and neck cancers. The risk of occult neck metastases for early‐stage OCCs ranges from 15% to 35%, hence the need to develop tools that can support the diagnosis of detecting these neck metastases.
Stefania Troise, Lorenzo Ugga, Maria Esposito, Maria Positano, Andrea Elefante, Serena Capasso, Renato Cuocolo, Raffaele Merola, Umberto Committeri, Vincenzo Abbate, Paola Bonavolontà, Riccardo Nocini, Giovanni Dell’Aversana Orabona   +12 more
wiley   +1 more source

Effect Of Bovine Colostrum On The Absolute Neutrophil Counts Of Acute Lymphocytic Leukemia Patients Undergoing Chemotherapy: A Double-Blind Randomized Placebo-Controlled Study [PDF]

, 2017
Edith Cyrill Caysido, Ferdinand P. Ganggangan, Rainelda Runez   +2 more
openalex   +1 more source

Predictor Accuracy of Absolute Neutrophil Count in Early Onset Sepsis

Annals of Pathology and Laboratory Medicine, 2018
Bipin H Chavda, Nirav S Panchal
openaire   +3 more sources

Association of baseline absolute neutrophil counts and survival in patients with metastatic colorectal cancer treated with second-line antiangiogenic therapies: exploratory analyses of the RAISE trial and validation in an electronic medical record data set [PDF]

, 2018
Axel Grothey, Takayuki Yoshino, G. Bodoky, Tudor–Eliade Ciuleanu, Rocio García‐Carbonero, Pilar García‐Alfonso, Eric Van Cutsem, Kei Muro, Daniel S. Mytelka, Li Li, Olga Lipkovich, Yanzhi Hsu, Andreas Sashegyi, David Ferry, Federico Nasroulah, Josep Tabernero   +15 more
openalex   +1 more source

Conversion therapy with sintilimab combined with chemotherapy and apatinib in stage IV gastric cancer

International Journal of Cancer, EarlyView.
What's New? In selected patients with stage IV gastric cancer, radical surgery after conversion therapy may increase survival benefit; however, there is currently no standard protocol for conversion therapy. This prospective, single‐arm, single‐center, phase 2 study evaluated the feasibility of adding immunotherapy to a conversion treatment regimen to ...
Yong Liu, Qiang Xue, Baogui Wang, Xuewei Ding, Rupeng Zhang, Xiaona Wang, Bin Ke, Xuejun Wang, Ning Liu, Jingyu Deng, Hongjie Zhan, Bin Li, Liangliang Wu, Mingzhi Cai, Li Zhang, Wenbai Huang, Peng Jin, Han Liang   +17 more
wiley   +1 more source

From multi‐omics to precision medicine in intracranial aneurysm: Biomarker discovery and multimodal integration

Interdisciplinary Medicine, EarlyView.
This review explores intracranial aneurysm biomarker discovery through multi‐omics. It reveals key genes, proteins, and metabolites, and shows how machine‐learning‐based multi‐modal integration may aid diagnosis and treatment. Abstract Despite extensive research, currently, no biomarkers are available for clinical use in intracranial aneurysm (IA ...
Jiaxin Zhang, Yufei Yang, Bingxu Chen, Yanmeng Zhao, Haitao Sun   +4 more
wiley   +1 more source