Results 51 to 60 of about 779,948 (264)
Frontiers in Cellular and Infection MicrobiologyIntroductionMany bacterial species in the viable but non-culturable (VBNC) state pose a considerable risk to public health, primarily because of their ability to persist and resuscitate in the environment and their enhanced ability to escape detection ...
Shuo Zhao +8 more
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The Influence of Absolute Mass Loading of Secondary Organic Aerosols on Their Phase State
Atmosphere, 2018 Absolute secondary organic aerosol (SOA) mass loading (CSOA) is a key parameter in determining partitioning of semi- and intermediate volatility compounds to the particle phase.
Shashank Jain +2 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
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Scandinavian Journal of Work, Environment & Health, 2017 OBJECTIVES: The study aimed to (i) determine the influence of poor health on competing exit routes from paid employment among older workers in Europe, (ii) assess whether these risks are different among welfare state regimes in Europe, and (iii) evaluate
Kerstin G Reeuwijk +4 more
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Absolute and conditional convergence within Sonora state municipalities, 1989- 2004
Estudios Fronterizos, 2008 This paper tries to identify the existence of convergence, absolut as muchas conditional, for the municipalities that conform the state of Sonora. Taking as abase the methodologic excercise of Mankiw, Romer and Weill (1992) that considersthe first model ...
Joaquín Bracamontes Neváre +1 more
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Distributed State Estimation for Bilinear Power System Models Based on Weighted Least Absolute Value
Applied SciencesAccurate, scalable, and outlier-robust state estimation (SE) is critical for large AC power systems with mixed SCADA and PMU measurements. This paper proposes D-BSE-L1, a distributed robust state estimator for the bilinear AC model.
Shijie Gao +3 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source