Results 51 to 60 of about 11,192,626 (307)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Topology Identification Method for Active Distribution Network Based on Weighted Minimum Absolute Value State Estimation

Zhongguo dianli
In the state estimation of distribution systems, it is difficult to fully monitor numerous network devices, resulting in insufficient measurement data. Besides, frequent topology switching urgently requires efficient algorithms.
Guang MA, Wen ZHU, Huijie GU, Huashi ZHAO, Xiqi HE, Shijie CHEN   +5 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

The Absolute: The Transition of the Premodern and Modern to the Postmodern in Understanding Self-sufficiency as the Absolute

Українське Pелігієзнавство, 2006
The statement of the problem of the article in the general form boils down to the fact that in modern philosophy, provided the postmodern Absolute is presented as a certain state of man, a certain state of consciousness of a self-sufficient nature.
Mykhailo G. Murashkin
doaj   +1 more source

Photonic microwave signals with zeptosecond-level absolute timing noise [PDF]

Nature Photonics, 2016
Ultralow-noise microwave signals are generated at 12 GHz by a low-noise fibre-based frequency comb and cutting-edge photodetection techniques. The microwave signals have a fractional frequency stability below 6.5 × 10–16 at 1 s and a timing noise floor ...
Xiaopeng Xie, R. Bouchand, D. Nicolodi, M. Giunta, W. Hänsel, M. Lezius, A. Joshi, S. Datta, C. Alexandre, M. Lours, P. Tremblin, G. Santarelli, R. Holzwarth, Y. Le Coq   +13 more
semanticscholar   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

STATE RESPONSIBILITY FOR LAWFUL ACTIVITIES: CONCEPTUAL GROUNDS

Ринкова економіка: сучасна теорія і практика управління, 2016
The article is devoted to the study of the theory of absolute liability in international law. Since the terms state responsibility and state liability are sometimes used as synonyms, it is important to make a difference because they present two different
С. С. Андрейченко
doaj   +1 more source

Absolute yeast mitochondrial proteome quantification reveals trade-off between biosynthesis and energy generation during diauxic shift

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance This work offers a unique portrayal of yeast mitochondria through the characterization of its absolute proteome. The study of biophysical changes in the mitochondrial network associated with proteome profiling, throughout yeast growth and ...
Francesca Di Bartolomeo, Carl Malina, Kate Campbell, Maurizio Mormino, J. Fuchs, E. Vorontsov, C. Gustafsson, J. Nielsen   +7 more
semanticscholar   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Absolute quantification of VBNC state formation and resuscitation in alcohol-producing Klebsiella pneumoniae

Frontiers in Cellular and Infection Microbiology
IntroductionMany bacterial species in the viable but non-culturable (VBNC) state pose a considerable risk to public health, primarily because of their ability to persist and resuscitate in the environment and their enhanced ability to escape detection ...
Shuo Zhao, Chenpu Dou, Chenpu Dou, Yang Yang, Jiazheng Wang, Meng Li, Bin Yang, Jing Yuan, Jian Zhang   +8 more
doaj   +1 more source