Results 61 to 70 of about 11,192,626 (307)
Scandinavian Journal of Work, Environment & Health, 2017 OBJECTIVES: The study aimed to (i) determine the influence of poor health on competing exit routes from paid employment among older workers in Europe, (ii) assess whether these risks are different among welfare state regimes in Europe, and (iii) evaluate
Kerstin G Reeuwijk +4 more
doaj +1 more source
The Influence of Absolute Mass Loading of Secondary Organic Aerosols on Their Phase State
Atmosphere, 2018 Absolute secondary organic aerosol (SOA) mass loading (CSOA) is a key parameter in determining partitioning of semi- and intermediate volatility compounds to the particle phase.
Shashank Jain +2 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Distributed State Estimation for Bilinear Power System Models Based on Weighted Least Absolute Value
Applied SciencesAccurate, scalable, and outlier-robust state estimation (SE) is critical for large AC power systems with mixed SCADA and PMU measurements. This paper proposes D-BSE-L1, a distributed robust state estimator for the bilinear AC model.
Shijie Gao +3 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Absolute and conditional convergence within Sonora state municipalities, 1989- 2004
Estudios Fronterizos, 2008 This paper tries to identify the existence of convergence, absolut as muchas conditional, for the municipalities that conform the state of Sonora. Taking as abase the methodologic excercise of Mankiw, Romer and Weill (1992) that considersthe first model ...
Joaquín Bracamontes Neváre +1 more
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Czech Journal of International Relations, 2010 The paper seeks to find the relationship between the philosophical debate on absolute and relative space and the IR debate on territoriality. It shows the relation between the absolute space concept and the territorial definition of the modern state. It
Tomáš Weiss
doaj
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source