Results 11 to 20 of about 3,631,195 (345)
Stem Cell Research & Therapy, 2017 Background Effective prevention and treatment of hypertrophic scars (HTSs), a common consequence of deep-partial thickness injury, remain a significant clinical challenge.
Philippe Foubert +6 more
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3D Printing of Mini Tablets for Pediatric Use
Pharmaceuticals, 2021 In the treatment of pediatric diseases, suitable dosages and dosage forms are often not available for an adequate therapy. The use of innovative additive manufacturing techniques offers the possibility of producing pediatric dosage forms.
Julius Krause +5 more
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An In Vitro Model to Investigate the Potential of Solid Dispersions to Form Pharmacobezoars
Pharmaceutics, 2022 The formation of pharmacobezoars from suspensions of spray-dried amorphous solid dispersions (SD-ASDs) of new chemical entities (NCEs) and hydroxypropyl methylcellulose acetate succinate (HPMC-AS) represents a non-compound related adverse effect in ...
Hannes Gierke +8 more
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The complex molecular absorption line system at z=0.886 towards PKS1830-211 [PDF]
, 1997 New millimeter wave observations of the molecular absorption line system in the gravitational lens to PKS1830-211 at z=0.88582 is presented. Self-calibrated interferometer data shows unequivocally that the previously detected absorption component is ...
Combes F. +13 more
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Influence of Siluron® insertion on model drug distribution in the simulated vitreous body
Current Directions in Biomedical Engineering, 2016 Biorelevant in vitro test systems may be helpful to understand the in vivo behaviour of modern intravitreal dosage forms such as implants and injections.
Stein Sandra +3 more
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Course of disease and risk factors for hospitalization in outpatients with a SARS-CoV-2 infection
Scientific Reports, 2022 We analyzed symptoms and comorbidities as predictors of hospitalization in 710 outpatients in North-East Germany with PCR-confirmed SARS-CoV-2 infection.
Eik Schäfer +18 more
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Pharmaceutics, 2023 Spray-dried amorphous solid dispersions of new chemical entities and pH-dependent soluble polymer hydroxypropyl methylcellulose acetate succinate (HPMC-AS) were found to form solid agglomerates in the gastrointestinal tract of rodents after oral ...
Hannes Gierke +12 more
doaj +1 more source
Mitochondrial reactive oxygen species modify extracellular vesicles secretion rate
FASEB BioAdvances, 2023 Extracellular vesicle (EV) secretion rate is stimulated by hypoxia that causes increased reactive oxygen species (ROS) production by the mitochondrial electron transport chain (ETC) and hypoxia‐induced factor (HIF)‐1 signaling; however, their ...
Mikkel Ø. Nørgård +6 more
doaj +1 more source
Pharmaceutics, 2023 The characterization of intravitreal dosage forms with regard to their behavior in vivo is usually explored in preclinical development through animal studies. In vitro vitreous substitutes (VS) to simulate the vitreous body for preclinical investigations
Tobias Auel +6 more
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