Results 11 to 20 of about 2,203,900 (197)
Calcium Absorption—A Paradigm for Mineral Absorption [PDF]
The Journal of Nutrition, 1998 Intestinal calcium absorption proceeds by two mechanisms, an active transcellular process that takes place in the duodenum and a passive paracellular process throughout the small intestine. This article characterizes the three steps of transcellular calcium movement-entry, intracellular diffusion and extrusion-and identifies conditions that must be ...
openaire +3 more sources
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
, 2000 This is the edited transcript of a Witness Seminar held at the Wellcome Institute for the History of Medicine,in London, on 9 February 1999. First published by the Wellcome Trust, 2000.
Christie, DA, Tansey, EM
core
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
FEBS Letters, EarlyView.miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan +10 more
wiley +1 more source
FEBS Letters, EarlyView.Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez +3 more
wiley +1 more source
Damped Lyman-alpha Absorption Associated with an Early-Type Galaxy at Redshift z = 0.16377
, 1997 We report new HST and ground-based observations of a damped Lyman-alpha absorption system toward the QSO 0850+4400. The redshift of the absorption system is z = 0.163770 and the neutral hydrogen column density of the absorption system is log N = 19.81 cm*
Altan, Hakan +10 more
core +1 more source
Evidence for Photoionization Driven Broad Absorption Line Variability [PDF]
, 2015 We present a qualitative analysis of the variability of quasar broad absorption lines using the large multi-epoch spectroscopic dataset of the Sloan Digital Sky Survey Data Release 10. We confirm that variations of absorption lines are highly coordinated
Ferland, Gary +3 more
core +3 more sources