Results 21 to 30 of about 1,016,885 (202)
On solar protons and polar cap absorption: Constraints on an empirical relationship [PDF]
, 2004 International audienceA large database of Solar Proton Events (SPE) from the period 1995 to 2001 is used to investigate the relationship between proton flux at geostationary orbit and Cosmic Noise Absorption (CNA) in the auroral zone. The effect of solar
A. Senior +9 more
core +2 more sources
Mitochondrial reactive oxygen species modify extracellular vesicles secretion rate
FASEB BioAdvances, 2023 Extracellular vesicle (EV) secretion rate is stimulated by hypoxia that causes increased reactive oxygen species (ROS) production by the mitochondrial electron transport chain (ETC) and hypoxia‐induced factor (HIF)‐1 signaling; however, their ...
Mikkel Ø. Nørgård +6 more
doaj +1 more source
Pharmaceutics, 2023 Spray-dried amorphous solid dispersions of new chemical entities and pH-dependent soluble polymer hydroxypropyl methylcellulose acetate succinate (HPMC-AS) were found to form solid agglomerates in the gastrointestinal tract of rodents after oral ...
Hannes Gierke +12 more
doaj +1 more source
Pharmaceutics, 2023 The characterization of intravitreal dosage forms with regard to their behavior in vivo is usually explored in preclinical development through animal studies. In vitro vitreous substitutes (VS) to simulate the vitreous body for preclinical investigations
Tobias Auel +6 more
doaj +1 more source
The Reno Aerosol Optics Study: An evaluation of aerosol absorption measurement methods [PDF]
, 2005 The Reno Aerosol Optics Study (RAOS) was designed and conducted to compare the performance of many existing and new instruments for the in situ measurement of aerosol optical properties with a focus on the determination of aerosol light absorption. For
Virkkula, Aki +11 more
core +1 more source
Geometric and scale effects on energy absorption of structural composites [PDF]
, 2011 PhDThe challenge faced by structural designers is becoming increasingly difficult as the imposed design criteria of energy absorbing structures requires weight reduction of structures without compromising cost and crushing performance.
Zhang, Chi. C.
core +4 more sources
Frontiers in Pharmacology, 2021 Genome-wide association studies have identified an association between isobutyrylcarnitine (IBC) and organic cation transporter 1 (OCT1) genotypes. Higher IBC blood concentrations in humans with active OCT1 genotypes and experimental studies with mouse ...
Ole Jensen +5 more
doaj +1 more source
International Journal of Pharmaceutics: XGastric emptying is a critical determinant of the pharmacokinetics of orally administered drugs. A key limitation in studies using caffeine as a marker for gastric emptying is the requirement for prior caffeine abstinence, which can complicate study ...
Toni Wildgrube +6 more
doaj +1 more source
Various effects of repeated rifampin dosing on coproporphyrin levels in humans
Clinical and Translational Science, 2023 In recent years, the identification of endogenous substrates as biomarkers became an uprising topic. Particularly coproporphyrins (CPs), byproducts of heme biosynthesis, are intensely investigated as biomarkers for predicting interactions with the ...
Jonny Kinzi +5 more
doaj +1 more source
Organic Cation Transporter 1 an Intestinal Uptake Transporter: Fact or Fiction?
Frontiers in Pharmacology, 2021 Intestinal transporter proteins are known to affect the pharmacokinetics and in turn the efficacy and safety of many orally administered drugs in a clinically relevant manner.
Christoph Wenzel +2 more
doaj +1 more source