Results 21 to 30 of about 1,836,494 (319)

Mitochondrial reactive oxygen species modify extracellular vesicles secretion rate

FASEB BioAdvances, 2023
Extracellular vesicle (EV) secretion rate is stimulated by hypoxia that causes increased reactive oxygen species (ROS) production by the mitochondrial electron transport chain (ETC) and hypoxia‐induced factor (HIF)‐1 signaling; however, their ...
Mikkel Ø. Nørgård, Philip M. Lund, Nazmie Kalisi, Thomas L. Andresen, Jannik B. Larsen, Stefan Vogel, Per Svenningsen   +6 more
doaj   +1 more source

Evaluation of Pharmacobezoar Formation from Suspensions of Spray-Dried Amorphous Solid Dispersions: An MRI Study in Rats

Pharmaceutics, 2023
Spray-dried amorphous solid dispersions of new chemical entities and pH-dependent soluble polymer hydroxypropyl methylcellulose acetate succinate (HPMC-AS) were found to form solid agglomerates in the gastrointestinal tract of rodents after oral ...
Hannes Gierke, Susan Mouchantat, Sabine Berg, Michael Grimm, Stefan Hadlich, Marie-Luise Kromrey, Thomas Nolte, Teresa Pfrommer, Vincent Rönnpagel, Adrian Rump, Kerstin Schaefer, Ann-Cathrin Willmann, Werner Weitschies   +12 more
doaj   +1 more source

Effect of sputtered silver thin film thickness towards morphological and optical properties of black silicon fabricated by two-step silver-assisted wet chemical etching for solar cells application [PDF]

Physics Access, 2022
Effect of sputtered silver (Ag) thin film thickness towards morphological and optical properties of black silicon (b-Si) fabricated by two-step silver-assisted wet chemical etching for solar cells applications is investigated.
Auwal Abdulkadir, Aliyu K Isiyaku, Mustapha Isah, Dallatu U Abbas, Tijjani Ismaila   +4 more
doaj   +1 more source

Ex Vivo Visualization of Distribution of Intravitreal Injections in the Porcine Vitreous and Hydrogels Simulating the Vitreous

Pharmaceutics, 2023
The characterization of intravitreal dosage forms with regard to their behavior in vivo is usually explored in preclinical development through animal studies. In vitro vitreous substitutes (VS) to simulate the vitreous body for preclinical investigations
Tobias Auel, Lara Paula Scherke, Stefan Hadlich, Susan Mouchantat, Michael Grimm, Werner Weitschies, Anne Seidlitz   +6 more
doaj   +1 more source

Characteristics of night-time absorption spike events [PDF]

, 2006
International audienceSudden increases in cosmic radio noise absorption, known as spike events, have been identified as signatures of substorms in the previous studies.
Viljanen, A., E. Spanswick, Kavanagh, A. J., A. Aminaei, A. J. Kavanagh, Spanswick, E., F. Honary, A. Viljanen, Honary, F., Aminaei, A.   +9 more
core   +1 more source

Isobutyrylcarnitine as a Biomarker of OCT1 Activity and Interspecies Differences in its Membrane Transport

Frontiers in Pharmacology, 2021
Genome-wide association studies have identified an association between isobutyrylcarnitine (IBC) and organic cation transporter 1 (OCT1) genotypes. Higher IBC blood concentrations in humans with active OCT1 genotypes and experimental studies with mouse ...
Ole Jensen, Johannes Matthaei, Henry G. Klemp, Marleen J. Meyer, Jürgen Brockmöller, Mladen V. Tzvetkov   +5 more
doaj   +1 more source

CO2 mitigation studies in packed absorption column using iron oxide nano fluid [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2023
The challenging task in our ecosystem is to reduce acidic gas emissions to some extent. Many gases are emitted from the industries like H2S, CO, CO2, SO2, NO, and NO2 as exhaust gases.
Selvi Pongayi Ponnusamy, Baskar Rajoo
doaj   +1 more source

Imaging riometer observations of drifting absorption patches in the morning sector [PDF]

, 2004
International audienceObservations by a 7x7-beam imaging riometer in Kilpisjärvi, Finland (~66° MLAT) of the drifting cosmic noise absorption (CNA) structures in the morning sector near the zonal drift reversals are presented.
V. S. C. Howells, Howells, V. S. C., Makarevitch, R. A., McCrea, I. W., F. Honary, I. W. McCrea, Honary, F., R. A. Makarevitch   +7 more
core   +1 more source

Various effects of repeated rifampin dosing on coproporphyrin levels in humans

Clinical and Translational Science, 2023
In recent years, the identification of endogenous substrates as biomarkers became an uprising topic. Particularly coproporphyrins (CPs), byproducts of heme biosynthesis, are intensely investigated as biomarkers for predicting interactions with the ...
Jonny Kinzi, Markus Grube, Karin Brecht, Isabell Seibert, Werner Siegmund, Henriette E. Meyer zu Schwabedissen   +5 more
doaj   +1 more source

Application of In Vivo Imaging Techniques and Diagnostic Tools in Oral Drug Delivery Research

Pharmaceutics, 2022
Drug absorption following oral administration is determined by complex and dynamic interactions between gastrointestinal (GI) physiology, the drug, and its formulation.
Stefan Senekowitsch, Philipp Schick, Bertil Abrahamsson, Patrick Augustijns, Thomas Gießmann, Hans Lennernäs, Christophe Matthys, Luca Marciani, Xavier Pepin, Alan Perkins, Maximilian Feldmüller, Sarah Sulaiman, Werner Weitschies, Clive G. Wilson, Maura Corsetti, Mirko Koziolek   +15 more
doaj   +1 more source