Results 21 to 30 of about 1,439 (152)

Meeting the Unmet Need in the Management of MDR Gram‐Positive Infections with Oral Bactericidal Agent Levonadifloxacin

Critical Care Research and Practice, Volume 2022, Issue 1, 2022., 2022
Levonadifloxacin (intravenous) and its oral prodrug alalevonadifloxacin are broad‐spectrum antibacterial agents developed for the treatment of difficult‐to‐treat infections caused by multidrug‐resistant Gram‐positive bacteria, especially methicillin‐resistant Staphylococcus aureus, atypical bacteria, anaerobic bacteria, and biodefence pathogens as well
Yatin Mehta, K. C. Mishra, Yashesh Paliwal, Pradeep Rangappa, Sharmili Sinha, Sandeep Bhapkar, Guowei Tu   +6 more
wiley   +1 more source

Necessity of vancomycin trough concentrations to manage uncomplicated acute bacterial skin and skin structure infections: a laboratory stewardship analysis

Drugs in Context, 2023
Background: Recent recommendations by the American Society of Health System Pharmacists and Infectious Disease Society of America have provided guidance regarding vancomycin dosing and monitoring in serious infections (including methicillin-resistant ...
Andrew Merker, Kartik Anne, Justin Rayyan, Milena Murray   +3 more
doaj   +1 more source

Unique Presentation of Septic Cavernous Sinus Thrombosis and Pulmonary Embolism in the Setting of Reusable Face Covering

Case Reports in Infectious Diseases, Volume 2022, Issue 1, 2022., 2022
Identified in December 2019, SARS‐CoV‐2 quickly spread worldwide with a resultant increase in global morbidity, mortality, and economic disruption on a scale not seen since the 1918 Spanish flu. Health officials recommended universal masking to further reduce human‐to‐human spread of SARS‐CoV‐2.
Javier Barranco-Trabi, Jazmin C. Scott, Jacob M. Fryer, Matthew Byrne, Adam Smith, Kaoru H. Song, Chelsea W. Tagawa, Sharon Chi, Viseth Ngauy, Larry M. Bush   +9 more
wiley   +1 more source

Use of oral tetracyclines in the treatment of adult outpatients with skin and skin structure infections: Focus on doxycycline, minocycline, and omadacycline

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 41, Issue 11, Page 915-931, November 2021., 2021
Abstract Oral tetracyclines have been used in clinical practice for over 60 years. One of the most common indications for use of oral tetracyclines is for treatment of adult outpatients with skin and soft infections (SSTIs), including acute bacterial skin and skin structure infections (ABSSSIs).
Monique R. Bidell, Thomas P. Lodise
wiley   +1 more source

Pathway with single‐dose long‐acting intravenous antibiotic reduces emergency department hospitalizations of patients with skin infections

Academic Emergency Medicine, Volume 28, Issue 10, Page 1108-1117, October 2021., 2021
Abstract Objectives Emergency department (ED) patients with serious skin and soft tissue infections (SSTIs) are often hospitalized to receive intravenous (IV) antibiotics. Appropriate patients may avoid admission following a single‐dose, long‐acting IV antibiotic.
David A. Talan, William R. Mower, Frank A. Lovecchio, Richard E. Rothman, Mark T. Steele, Katelyn Keyloun, Patrick Gillard, Ronald Copp, Gregory J. Moran, Damon R. Kuehl   +9 more
wiley   +1 more source

The use of extrapolation based on modeling and simulation to support high‐dose regimens of ceftaroline fosamil in pediatric patients with complicated skin and soft‐tissue infections

CPT: Pharmacometrics &Systems Pharmacology, Volume 10, Issue 6, Page 551-563, June 2021., 2021
Abstract A model‐informed drug development approach was used to select ceftaroline fosamil high‐dose regimens for pediatric patients with complicated skin and soft‐tissue infections caused by Staphylococcus aureus with a ceftaroline minimum inhibitory concentration (MIC) of 2 or 4 mg/L.
Phylinda L.S. Chan, Lynn McFadyen, Andrea Quaye, Heidi Leister‐Tebbe, Victoria M. Hendrick, Jennifer Hammond, Susan Raber   +6 more
wiley   +1 more source

Emergency department care of ABSSSI with dalbavancin infusion, direct discharge, and outpatient telemedicine follow up: a study protocol

, 2023
Novel therapeutic strategies such as the long-acting lipoglycopeptide antibiotics allow for the treatment and discharge of selected emergency department (ED) patients with Acute Bacterial Skin and Skin Structure Infections (ABSSSI), who require ...
Mario Guarino, Cesaro, Flavio, Riccardi, Alessandro, Guarino, Mario, Lugarà, Marina, Natale, Vincenzo, Morelli, Lucia, Emanuele Durante-Mangoni, Flavio Cesaro, Marina Lugarà, Alessandro Riccardi, Vincenzo Natale, Silvia Mascolo, Mascolo, Silvia, Lucia Morelli, Durante-Mangoni, Emanuele, Andreoni, Massimo, Massimo Andreoni   +17 more
core   +1 more source

Financial Analysis of Dalbavancin for Acute Bacterial Skin and Skin Structure Infections for Self-Pay Patients

Infectious Diseases and Therapy, 2020
Introduction Acute bacterial skin and skin structure infections (ABSSSI) are an increasing cause of admission in the self-pay population. We previously reported that patients with ABSSSI discharged to receive dalbavancin showed a decreased length of stay
Adam G. Pizzuti, E. Yancy Murray, Jamie L. Wagner, Derek A. Gaul, Christopher M. Bland, Bruce M. Jones   +5 more
doaj   +1 more source

Kimyrsa and Orbactiv – A Tale of Two Formulations

Drug Design, Development and Therapy, 2023
Brittany T Jackson,1 David B Cluck,2 Andrés F Henao-Martínez,3 Daniel B Chastain4 1Department of Pharmacy, Mount Sinai Morningside, New York, NY, 10025, USA; 2Department of Pharmacy Practice, Bill Gatton College of Pharmacy East Tennessee State ...
Jackson BT, Cluck DB, Henao-Martínez AF, Chastain DB   +3 more
doaj  

Tackling Extended Hospital Stays in Patients with Acute Bacterial Skin and Skin Structure Infections

European Medical Journal, 2022
Hospitalisation rates for acute bacterial skin and skin structure infection (ABSSSI) are rising and represent a large pharmacoeconomic burden as treatment may involve an extended number of days of antibiotic therapy. This article first aims to provide a
Gavin Barlow, Michael Wilke, Guillaume Béraud   +2 more
doaj   +1 more source