Results 111 to 120 of about 2,953,114 (317)

Non-perturbative Effect on Thermal Relic Abundance of Dark Matter

open access: yes, 2006
We point out that thermal relic abundance of the dark matter is strongly altered by a non-perturbative effect called the Sommerfeld enhancement, when constituent particles of the dark matter are non-singlet under the SU(2)_L gauge interaction and much ...
Appelquist   +23 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Influence of Cooling Flow and Galactic Motion on the Iron Distribution in Clusters of Galaxies

open access: yes, 1994
Iron abundance distribution is now known for 12 clusters of galaxies. For some clusters (e.g. Centaurus) the observed abundance increases toward the cluster center, while for the others (e.g.
Fujita, Yutaka, Kodama, Hideo
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Project VeSElkA: Search for vertical stratification of element abundances in HD157087

open access: yes, 2018
The new spectropolarimetric spectra of HD157087 obtained recently with ESPaDOnS at CFHT are analysed to verify the nature of this object. The fundamental stellar parameters $T_{\rm eff}$ = 8882 K, $\log{g}$=3.57 have been obtained for HD157087 from the ...
Khalack, Viktor
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Rieske FeS overexpression in tobacco provides increased abundance and activity of cytochrome b 6 f [PDF]

open access: hybrid, 2022
Eiri Heyno   +8 more
openalex   +1 more source

Chemical abundances of LINER galaxies – nitrogen abundance estimations

open access: yesMonthly Notices of the Royal Astronomical Society
ABSTRACT In this work, we investigated the nitrogen and oxygen abundances in a sample of galaxies with Low Ionization Nuclear Emission Regions (LINERs) in their nucleus. Optical spectroscopic data (3600 – 10 000 Å) of 40 LINERs from the Mapping Nearby Galaxies (MaNGAs) survey were considered.
C B Oliveira   +7 more
openaire   +3 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

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