Results 101 to 110 of about 612,500 (304)

Chemical Abundances Of Open Clusters From High-Resolution Infrared Spectra. I. NGC 6940

, 2019
We present near-infrared spectroscopic analysis of 12 red giant members of the Galactic open cluster NGC 6940. High-resolution (R$\simeq$45000) and high signal-to-noise ratio (S/N > 100) near-infrared H and K band spectra were gathered with the Immersion
Afşar, M, Denissenkov, P A, Jaffe, D T, Kim, H, Mace, G N, Pilachowski, C A, Sneden, C, Sokal, K R, Strickland, E, Topcu, G Böcek, VandenBerg, D A, Wright, D   +11 more
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

On the nuclear robustness of the r process in neutron-star mergers

, 2015
We have performed r-process calculations for matter ejected dynamically in neutron star mergers based on a complete set of trajectories from a three-dimensional relativistic smoothed particle hydrodynamic simulation. Our calculations consider an extended
Bauswein, Andreas, Janka, Hans-Thomas, Langanke, Karlheinz, Martínez-Pinedo, Gabriel, Mendoza-Temis, Joel de Jesús, Wu, Meng-Ru   +5 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Solar and stellar photospheric abundances

Living Reviews in Solar Physics, 2016
The determination of photospheric abundances in late-type stars from spectroscopic observations is a well-established field, built on solid theoretical foundations.
Carlos Allende Prieto
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Generalized Te([O iii])–Te(He i) Discrepancies in Ionized Nebulae: Possible Evidence of Case B Deviations and Temperature Inhomogeneities

The Astrophysical Journal
The physics of recombination lines in the He i singlet system is expected to be relatively simple, supported by accurate atomic models. We examine the intensities of He i singlets λ 3614,  λ 3965,  λ 5016,  λ 6678, and  λ 7281 and the triplet He i λ 5876
J. E. Méndez-Delgado, E. D. Skillman, E. Aver, C. Morisset, C. Esteban, J. García-Rojas, K. Kreckel, N. S. J. Rogers, F. F. Rosales-Ortega, K. Z. Arellano-Córdova, S. R. Flury, E. Reyes-Rodríguez, M. Orte-García, S. Tan   +13 more
doaj   +1 more source

Religion, poverty, and abundance [PDF]

, 2018
Anna Sofia Salonen
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

A Systematic NLTE Study of Very Metal-poor Stars with Metallicity down to −4.3 dex. I. Global Stellar Parameters Based on High-resolution Spectra

The Astrophysical Journal
Very metal-poor (VMP) stars provide a record of the chemical composition and dynamics of the early Galaxy. Based on the high-resolution and high signal-to-noise ratio spectra from the Subaru Telescope for 103 VMP stars, in this series of papers we ...
Jianrong Shi, Gang Zhao, Shuai Liu, Zeming Zhou, Haining Li, Hongliang Yan, Sofya Alexeeva, Huawei Zhang, Wako Aoki, Tadafumi Matsuno, Jingkun Zhao, Huiling Chen, Yufu Shen   +12 more
doaj   +1 more source