Results 11 to 20 of about 1,169,779 (313)

Substance Abuse and Mental Health Services Administration

open access: yesDefinitions, 2020
Submitted to: Maureen Madison, Ph.D. Public Health Advisor Division of Prevention, Traumatic Stress, and Special Programs Center for Mental Health Services Administration 1 Choke Cherry Road, 6-1100 Rockville, MD 20857 Phone: 240-276-1772 maureen.madison@
Kimberly Kendziora   +5 more
semanticscholar   +1 more source

Risk and protective factors of drug abuse among adolescents: a systematic review

open access: yesBMC Public Health, 2021
Drug abuse is detrimental, and excessive drug usage is a worldwide problem. Drug usage typically begins during adolescence. Factors for drug abuse include a variety of protective and risk factors. Hence, this systematic review aimed to determine the risk
A. Nawi   +7 more
semanticscholar   +1 more source

National Institute on Alcohol Abuse and Alcoholism

open access: yesDefinitions, 2020
There is evidence that approximately 90 percent of alcoholics are likely to experience at least one relapse over the 4-year period following treatment (1). Despite some promising leads, no controlled studies definitively have shown any single or combined
Jennifer A. Pellowski
semanticscholar   +1 more source

Orbitofrontal cortex microRNAs support long-lasting heroin seeking behavior in male rats

open access: yesTranslational Psychiatry, 2023
Recovery from opioid use disorder (OUD) and maintenance of abstinence from opioid use is hampered by perseverant drug cravings that may persist for months after cessation of drug use. Drug cravings can intensify during the abstinence period, a phenomenon
Mary Tresa Zanda   +2 more
doaj   +1 more source

National Institute on Drug Abuse

open access: yesDefinitions, 2020
An institute within the National Institutes of Health with the mission to lead the nation in bringing the power of science to bear on drug abuse and addiction. T his charge has two critical components, the strategic support and conduct of research across
N. D. Volkow
semanticscholar   +1 more source

Parental supply of alcohol to Australian minors: an analysis of six nationally representative surveys spanning 15 years

open access: yesBMC Public Health, 2016
Background Most adolescents begin alcohol consumption during adolescence, heavy alcohol use by adolescents is common, and alcohol-related harm amongst adolescents is a major public health burden. Parents are a common source of alcohol amongst adolescents,
Adrian B. Kelly   +6 more
doaj   +1 more source

Medial prefrontal cortex and anteromedial thalamus interaction regulates goal-directed behavior and dopaminergic neuron activity

open access: yesNature Communications, 2022
The prefrontal cortex is involved in goal-directed behaviour. Here the authors show that medial prefrontal cortex activates goal-directed motivation and dopamine neurons via a feedback loop with the anteromedial thalamus.
Chen Yang   +20 more
doaj   +1 more source

Functional Connectivity Hubs and Networks in the Awake Marmoset Brain

open access: yesFrontiers in Integrative Neuroscience, 2016
In combination with advances in analytical methods, resting-state fMRI is allowing unprecedented access to achieve a better understanding of the network organization of the brain. Increasing evidence suggests that this architecture may incorporate highly
Annabelle Marie Belcher   +10 more
doaj   +1 more source

The Long-Term Health Consequences of Child Physical Abuse, Emotional Abuse, and Neglect: A Systematic Review and Meta-Analysis

open access: yesPLoS Medicine, 2012
Rosana Norman and colleagues conduct a systematic review and meta-analysis to assess the relationship between child physical abuse, emotional abuse, and neglect, and subsequent mental and physical health outcomes.
Rosana E Norman   +5 more
semanticscholar   +1 more source

Gs- versus Golf-dependent functional selectivity mediated by the dopamine D1 receptor

open access: yesNature Communications, 2018
D1-like dopamine receptors are coupled to Golf proteins in the dorsal striatum but Gs in cortical and other areas. Here, the authors demonstrate selective agonism of Gs-coupled versus Golf-coupled D1 receptors.
Hideaki Yano   +9 more
doaj   +1 more source

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