Results 11 to 20 of about 535,088 (168)
The psychological impacts of content moderation on content moderators: A qualitative study
Cyberpsychology: Journal of Psychosocial Research on Cyberpspace, 2023 Content moderation generally refers to the practice of monitoring user generated content and applying a set of rules defining what is acceptable. As a result, Content Moderators (CMs) are responsible for reviewing and removing harmful online material ...
Ruth Spence +4 more
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Orbitofrontal cortex microRNAs support long-lasting heroin seeking behavior in male rats
Translational Psychiatry, 2023 Recovery from opioid use disorder (OUD) and maintenance of abstinence from opioid use is hampered by perseverant drug cravings that may persist for months after cessation of drug use. Drug cravings can intensify during the abstinence period, a phenomenon
Mary Tresa Zanda +2 more
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BMC Public Health, 2016 Background Most adolescents begin alcohol consumption during adolescence, heavy alcohol use by adolescents is common, and alcohol-related harm amongst adolescents is a major public health burden. Parents are a common source of alcohol amongst adolescents,
Adrian B. Kelly +6 more
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Nature Communications, 2022 The prefrontal cortex is involved in goal-directed behaviour. Here the authors show that medial prefrontal cortex activates goal-directed motivation and dopamine neurons via a feedback loop with the anteromedial thalamus.
Chen Yang +20 more
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Functional Connectivity Hubs and Networks in the Awake Marmoset Brain
Frontiers in Integrative Neuroscience, 2016 In combination with advances in analytical methods, resting-state fMRI is allowing unprecedented access to achieve a better understanding of the network organization of the brain. Increasing evidence suggests that this architecture may incorporate highly
Annabelle Marie Belcher +10 more
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Gs- versus Golf-dependent functional selectivity mediated by the dopamine D1 receptor
Nature Communications, 2018 D1-like dopamine receptors are coupled to Golf proteins in the dorsal striatum but Gs in cortical and other areas. Here, the authors demonstrate selective agonism of Gs-coupled versus Golf-coupled D1 receptors.
Hideaki Yano +9 more
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Frontiers in Psychiatry, 2019 Opioid use in the United States has steadily risen since the 1990s, along with staggering increases in addiction and overdose fatalities. With this surge in prescription and illicit opioid abuse, it is paramount to understand the genetic risk factors and
Jamie A. Burns +8 more
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Trend in alcohol use in Australia over 13 years: has there been a trend reversal?
BMC Public Health, 2016 Background Skog’s collectivity theory of alcohol consumption predicted that changes in alcohol consumption would synchronize across all types of drinkers in a population. The aim of this paper is examine this theory in the Australian context. We examined
Gary C.K. Chan +9 more
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Drug-associated cues and drug dosage contribute to increased opioid seeking after abstinence
Scientific Reports, 2021 Patients with opioid use disorder experience high rates of relapse during recovery, despite successful completion of rehabilitation programs. A key factor contributing to this problem is the long-lasting nature of drug-seeking behavior associated with ...
Mary Tresa Zanda +2 more
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Hepatitis Infection in the Treatment of Opioid Dependence and Abuse
Substance Abuse: Research and Treatment, 2008 Many new and existing cases of viral hepatitis infections are related to injection drug use. Transmission of these infections can result directly from the use of injection equipment that is contaminated with blood containing the hepatitis B or C virus or
Thomas F. Kresina +6 more
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